During the past decade many review papers and books have been devoted to descriptions and analyses of biological rhythms (chronobiology) in plants and animals. These contributed greatly to demonstrating the impor tance of bioperiodicities in living beings in general. However, the practi cal aspects of chronobiology with regard to human health and improving the treatment of disease have not yet been a major focus of publication. One of our aims is to establish the relevance of biological rhythms to the practice of medicine. Another is to organize and convey in a simple fashion information pertinent to health- and life-science professionals so that students, researchers, and practitioners can achieve a clear and pre cise understanding of chronobiology. We have limited scientific jargon to unavoidable basic and well-defined terms and we have emphasized illus trative examples of facts and concepts rather than theories or hypotheti cal mechanisms. This volume is divided into seven chapters, each of which is compre hensive in its treatment and includes an extensive bibliography. The book is organized to serve as a textbook and/or reference handbook of modem applied chronobiology. Chapter 1 describes the historical development of chronobiology and reviews why, when, and how major concepts were introduced, accepted, and transformed.

In this important and controversial book, one of our leading literary theorists presents a major philosophical statement about the meaning of literature and the shape of literary texts. Drawing on works by the Russian writers Dostoevsky, Tolstoy, and Chekhov, by other writers as diverse as Sophocles, Cervantes, and George Eliot, by thinkers as varied as William James, Mikhail Bakhtin, and Stephen Jay Gould, and from philosophy, the Bible, television, and much more, Gary Saul Morson examines the relation of time to narrative form and to an ethical dimension of the literary experience. Morson asserts that the way we think about the world and narrate events is often in contradiction to the truly eventful and open nature of daily life. Literature, history, and the sciences frequently present experience as if contingency, chance, and the possibility of diverse futures were all illusory. As a result, people draw conclusions or accept ideologies without sufficiently examining their consequences or alternatives. However, says Morson, there is another way to read and construct texts. He explains that most narratives are developed through foreshadowing and "backshadowing" (foreshadowing ascribed after the fact), which tend to reduce the multiplicity of possibilities in each moment. But other literary works try to convey temporal openness through a device he calls "sideshadowing." Sideshadowing suggests that to understand an event is to grasp what else might have happened. Time is not a line but a shifting set of fields of possibility. Morson argues that this view of time and narrative encourages intellectual pluralism, helps to liberate us from the false certainties of dogmatism, creates a healthy skepticism of present orthodoxies, and makes us aware that there are moral choices available to us.

by Fred Wendorf and Romuald Schild The Eastern Sahara is a fascinating place to study structures. These larger, more complex sites are almost prehistory. Confronted with the stark reality of a hyper always in the lower parts of large basins, most of which arid environment that receives no measurable rainfall, were formed by deflation during the Late Pleistocene lacks vegetation, and is seemingly without life, it would hyper-arid interval between about 65,000 and 13,000 seem to be an unlikely place to find a rich and complex years ago. Their location near the floor of these basins mosaic of archaeological remains documenting past was influenced primarily by one factor - water. During human presence. Despite this impression of a hostile wet phases, runoff from extensive catchment areas environment, there is widespread and abundant caused the development of large, deep, seasonal lakes, archaeological evidence. or playas, in the lowermost parts of these basins. This It is obvious that this area was not always a lifeless surface water would last for several weeks or months desert. Faunal and plant remains found in the excavations after the seasonal rains, and by digging wells after the at Holocene-age settlements, dating between 9500 and playa became dry, water could still be obtained during 5000 radiocarbon years ago, indicate that rainfall during most, if not all, of the dry season.

This collection of articles honoring eminent classicist and historian Louis H. Feldman brings together a host of prominent scholars from all over the world writing on such fields as biblical interpretation, Judaism and Hellenism, Jews and Gentiles, Josephus, Jewish Literatures of the Second Temple, Mishnah and Talmud periods, History of the Mishnah and Talmud periods, Jerusalem and much more.

The Carbiocial Project investigates viable carbon-optimized land management strategies for maintaining tropical ecosystem services under land use change and changing climate conditions in Southern Amazonia – a hotspot of global change. The project aims at understanding the vital natural processes and socio-economic driving forces in the region and develops strategies to enhance and protect carbon stocks in the recently deforested agroscapes of Central/Northern Mato Grosso and South Pará. That is why Carbiocial analyzes and models soil, water and climate as well as agro-economics, social and political transformations. Based on detailed storylines, the project aims at identifying possible entry-points for a necessary change in local and regional production patterns, considering local livelihoods as well as the present national and global economic, legal and political situation. This book gives an overview of the first results of the multi-disciplinary Carbiocial Project by publishing the main presentations, held on the Carbiocial Status Conference, on October 7-8, 2013, in Cuiabá. In sixteen chapters the authors elucidate the project‘s current state of knowledge, illustrating adapted methods for regional modeling and promising strategies for the Amazon development.

1.1. Definition of Terms-Thrombosis, Thromboembolic Disease, Atherosclerosis, and Blood Clotting The terms heart attack or myocardial infarction are more commonly used than thrombosis. The infarct-muscle destruction is simply the end result and thrombosis is the real cause of the heart attack. Thrombosis may be defined as the process of formation of a coalescent or agglutinated solid mass of blood components in the blood stream. Thrombi formed in either arteries or veins often cause occlusion in the vascular system and prevent blood flow. Obstruc to the blood vessel usually occurs at the site where the thrombi deposit. tion Furthermore, thrombi may break loose, travel through the circulating blood stream, and cause obstruction at some distal point of narrowing elsewhere. The mass or thrombus that moves is referred to as an "embolus." The two phenomena are lumped together under the term thromboembolic disease. Thrombosis that reduces blood supply to the heart is the primary factor in heart attacks.