The first edition of Introduction to Pharmacology has over recent years become a highly influential text among students wishing to acquire a knowledge of pharmacology without having to refer to the larger, more detailed, traditional pharmacology volumes. This revised and updated second edition contains significant new material to bring the reader up-to-date with the latest practices and principles in pharmacology. Exploring the basic principles in both the therapeutic and toxicological aspects of drug use, the book employs contemporary examples of medication, supplemented with an increased number of accurate and easy-to-interpret figures and diagrams. Additionally, Introduction to Pharmacology presents the important concept of understanding the limitations surrounding the drugs that cure, replace physiological inadequacies, or treat symptoms, and which have led to the system of drug classification. The broad scope of the book also encompasses the role of the FDA, drugs in sport, and the use of animals for drug experimentation. A clear and accessible book, Introduction to Pharmacology builds on the strengths of the first edition and is an invaluable reference for all students interested in this subject.

Advances in pharmacogenomics and proteomics, along with the introduction of recombinant DNA technology, have expanded the applications of pharmacology to encompass a range of disciplines. Biomedical researchers, protein specialists, and molecular biologists are all involved in the development and delivery of novel drugs. Therefore, students in a va

Aside from a general updating of material, this text re-writes the chapter on memory and learning to emphasize the idea that the genes that are involved in behaviour are not immutable but their expression can be modified by transcription factors.

This book is the second of two volumes devoted to the work of Theo Kuipers, a leading Dutch philosopher of science. Philosophers and scientists from all over the world, thirty seven in all, comment on Kuipers' philosophy, and each of their commentaries is followed by a reply from Kuipers. The present volume is devoted to Kuipers' neo-classical philosophy of science, as laid down in his Structures in Science (Kluwer, 2001). Kuipers defends a dialectical interaction between science and philosophy in that he views philosophy of science as a meta-science which formulates cognitive structures that provide heuristic patterns for actual scientific research, including design research. In addition, Kuipers pays considerable attention to the computational approaches to philosophy of science as well as to the ethics of doing research. Thomas Nickles, David Atkinson, Jean-Paul van Bendegem, Maarten Franssen, Anne Ruth Mackor, Arno Wouters, Erik Weber & Helena de Preester, Eric Scerri, Adam Grobler & Andrzej Wisniewski, Alexander van den Bosch, Gerard Vreeswijk, Jaap Kamps, Paul Thagard, Emma Ruttkamp, Robert Causey, Henk Zandvoort comment on these ideas of Kuipers, and many present their own account. The present book also contains a synopsis of Structures in Science. It can be read independently of the first volume of Essays in Debate with Theo Kuipers, which is devoted to Kuipers' From Instrumentalism to Constructive Realism (2000).

There are hundreds, if not thousands, of substances that are used to modify behavior. While different classes of substances have known effects, one has only to see a group of people drinking to excess to recognize that not everyone responds in the same way to a given substance. Why do substances have the behavioral effects they do, and why do individuals vary in their responses to them? This book provides a conceptual framework for answering such questions. Introduction to Behavioral Pharmacology includes a short overview of behavioral analysis and general pharmacology, followed by detailed discussion of assessment of drug effects, the stimulus properties of drugs, drug abuse, and more.

Pharmacology is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Pharmacology is the study of the actions of chemicals on the body and most usually it is defined as chemicals that can have a therapeutic action to treat disease. Since it looks at the interaction between chemicals and body systems pharmacology utilizes the basic disciplines of chemistry, biochemistry, physiology, pathology and microbiology in its practice. Pharmacology is a foundation science for pharmacy which is the rational prescribing of drugs to treat disease and the foundation science for toxicology which is the study of the toxic actions of chemicals on the body. The two volumes are organized in groups of chapters as follows: The first group of chapters discuss pharmacological principles and these include chapters on Pharmacodynamics; Pharmacokinetics, Neuropharmacology, Autonomic Pharmacology and Clinical Pharmacology. The second group of chapters discusses the processes of Drug discovery and the Safety requirements for drugs to be used therapeutically and include Drug Discovery and Safety Pharmacology assessment. The largest group of chapters discuss different therapeutic areas and include Cardiovascular and renal pharmacology; Endocrine pharmacology; Neuropsychopharmacology; Pulmonary Pharmacology; Gastrointestinal pharmacology; Poisons venoms and toxins; Drugs on skeletal muscle; the Pharmacotherapy of inflammation; Reproductive pharmacology; Pain pharmacology and analgesia. The final group of chapters discuss new approaches and include Pharmacogenetics and pharmacogenomics; Immunopharmacology and Gene therapy. These two volumes are aimed at the following a wide spectrum of audiences from the merely curious to those seeking in-depth knowledge: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.

More detailed than an outlined review but less overwhelming than an encyclopedic reference, Brenner and Stevens' Pharmacology, 6th Edition, focuses on the essential principles you need to know in a concise, easy-to-understand manner. Authored by Craig W. Stevens, PhD, this highly illustrated introductory text helps you learn and retain key information in pharmacology—taking you from course exams and the USMLE Step 1 right through to clinical practice. New and extensively revised content keeps you up to date with the latest pharmacologic mechanisms and applications. - Teaches the fundamental aspects of pharmacology using full-color illustrations, detailed explanations, and a consistent format to present classification of drugs for each system/disease. - Helps you understand both the basic science foundations and clinical applications of pharmacology, with useful tables, drug classifications boxes, case studies, and self-assessments in each chapter to help you review and prepare for course exams and Step 1. - Includes the latest drugs and therapeutic indications (more than 100 are new to this edition), along with an entirely new chapter on recent developments of immunopharmacology drugs, including antivirals and vaccinations. - Addresses key topics such as antiviral and monoclonal drugs to treat COVID-19, the opioid epidemic, and gene therapy. - Features more than 700 new and updated images, with many revised figures focused on clearing presenting the mechanism of action of drugs. - Includes access to bonus eBook content such as animations, an additional glossary, chapter-by-chapter summaries and case studies, a full list of featured drugs, 150 USMLE-style self-assessment questions, and more.

Designer drugs, or new psychoactive substances (NPS), are synthetic chemicals that mimic the effects of classic drugs of abuse. There has been an alarming worldwide increase in the abuse of NPS in recent years. NPS are cheap, easy to obtain, and often legally available. In this volume, leading experts summarize the latest studies regarding the molecular mechanisms of action, behavioral effects, and adverse consequences of popular NPS. Specific chapters clarify the differences between various types of NPS, namely: stimulants, cannabinoids and hallucinogens. Thus, this volume broadens our understanding of NPS and provides insight into the rapidly evolving “new drug” phenomenon.

Medical and Health Sciences is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. These volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the fields of Medical and Health Sciences and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs.

Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient. Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text: Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty