If you are a web developer working with geospatial concepts and mapping APIs, and you want to learn Leaflet to create mapping solutions, this book is for you. You need to have a basic knowledge of working with JavaScript and performing web application development.

Mitral regurgitation (MR) affects millions of patients worldwide. It is a progressive condition that can worsen when left untreated, possibly leading to compensatory remodeling of the left ventricle. This can result in reduced functional capacity, poor quality of life, repeat hospitalizations, and even death from heart failure. Open, arrested heart

This report by the Committee on Safety of Medicines (CSM) Working Group on Patient Information focuses on three main issues: to advise on strategies to improve the quality of information provided with medicines within the regulatory environment to meet patients needs; to propose criteria to assess and monitor the quality of patient information to ensure the safe and appropriate use of medicines; and to advise on key cases which could impact significantly on public health and which will set standards for other products. A number of recommendations are made in relation to the following issues: patient involvement; the quality of patient information leaflets (PILs); risk communication; accessibility of information about medicine taking; regulatory needs; patients needs; public awareness aspects; and impact assessment.