Multistate Analysis Of Life Histories With R

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This book provides an introduction to multistate event history analysis. It is an extension of survival analysis, in which a single terminal event (endpoint) is considered and the time-to-event is studied. Multistate models focus on life histories or trajectories, conceptualized as sequences of states and sequences of transitions between states. Life histories are modeled as realizations of continuous-time Markov processes. The model parameters, transition rates, are estimated from data on event counts and populations at risk, using the statistical theory of counting processes. The Comprehensive R Network Archive (CRAN) includes several packages for multistate modeling. This book is about Biograph. The package is designed to (a) enhance exploratory analysis of life histories and (b) make multistate modeling accessible. The package incorporates utilities that connect to several packages for multistate modeling, including survival, eha, Epi, mvna,, mstate, msm, and TraMineR for sequence analysis. The book is a ‘hands-on’ presentation of Biograph and the packages listed. It is written from the perspective of the user. To help the user master the techniques and the software, a single data set is used to illustrate the methods and software. It is the subsample of the German Life History Survey, which was also used by Blossfeld and Rohwer in their popular textbook on event history modeling. Another data set, the Netherlands Family and Fertility Survey, is used to illustrate how Biograph can assist in answering questions on life paths of cohorts and individuals. The book is suitable as a textbook for graduate courses on event history analysis and introductory courses on competing risks and multistate models. It may also be used as a self-study book. The R code used in the book is available online. Frans Willekens is affiliated with the Max Planck Institute for Demographic Research (MPIDR) in Rostock, Germany. He is Emeritus Professor of Demography at the University of Groningen, a Honorary Fellow of the Netherlands Interdisciplinary Demographic Institute (NIDI) in the Hague, and a Research Associate of the International Institute for Applied Systems Analysis (IIASA), Laxenburg, Austria. He is a member of Royal Netherlands Academy of Arts and Sciences (KNAW). He has contributed to the modeling and simulation of life histories, mainly in the context of population forecasting.

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Genre : Mathematics
Author : Frans Willekens
Publisher : Springer
Release : 2014-09-11
File : 323 Pages
ISBN-13 : 9783319083834


Life Histories Of Genetic Disease

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A richly detailed history that “uncovers the challenges and limitations of our increasing reliance on genetic data in medical decision making” (Shobita Parthasarathy, author of Building Genetic Medicine). Medical geneticists began mapping the chromosomal infrastructure piece by piece in the 1970s by focusing on what was known about individual genetic disorders. Five decades later, their infrastructure had become an edifice for prevention, allowing expectant parents to test prenatally for hundreds of disease-specific mutations using powerful genetic testing platforms. In this book, Andrew J. Hogan explores how various diseases were “made genetic” after 1960, with the long-term aim of treating and curing them using gene therapy. In the process, he explains, these disorders were located in the human genome and became targets for prenatal prevention, while the ongoing promise of gene therapy remained on the distant horizon. In narrating the history of research that contributed to diagnostic genetic medicine, Hogan describes the expanding scope of prenatal diagnosis and prevention. He draws on case studies of Prader-Willi, fragile X, DiGeorge, and velo-cardio-facial syndromes to illustrate that almost all testing in medical genetics is inseparable from the larger—and increasingly “big data”–oriented—aims of biomedical research. Hogan also reveals how contemporary genetic testing infrastructure reflects an intense collaboration among cytogeneticists, molecular biologists, and doctors specializing in human malformation. Hogan critiques the modern ideology of genetic prevention, which suggests all pregnancies are at risk for genetic disease and should be subject to extensive genomic screening. He examines the dilemmas and ethics of the use of prenatal diagnostic information in an era when medical geneticists and biotechnology companies offer whole genome prenatal screening—essentially searching for any disease-causing mutation. Hogan’s analysis is animated by ongoing scientific and scholarly debates about the extent to which the preventive focus in contemporary medical genetics resembles the aims of earlier eugenicists. Written for historians, sociologists, and anthropologists of science and medicine, as well as bioethics scholars, physicians, geneticists, and families affected by genetic conditions, Life Histories of Genetic Disease is a profound exploration of the scientific culture surrounding malformation and mutation.

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Genre : Medical
Author : Andrew J. Hogan
Publisher : Johns Hopkins University Press+ORM
Release : 2016-10-30
File : 264 Pages
ISBN-13 : 9781421420752


The Routledge International Handbook On Narrative And Life History

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In recent decades, there has been a substantial turn towards narrative and life history study. The embrace of narrative and life history work has accompanied the move to postmodernism and post-structuralism across a wide range of disciplines: sociological studies, gender studies, cultural studies, social history; literary theory; and, most recently, psychology. Written by leading international scholars from the main contributing perspectives and disciplines, The Routledge International Handbook on Narrative and Life History seeks to capture the range and scope as well as the considerable complexity of the field of narrative study and life history work by situating these fields of study within the historical and contemporary context. Topics covered include: • The historical emergences of life history and narrative study • Techniques for conducting life history and narrative study • Identity and politics • Generational history • Social and psycho-social approaches to narrative history With chapters from expert contributors, this volume will prove a comprehensive and authoritative resource to students, researchers and educators interested in narrative theory, analysis and interpretation.

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Genre : Education
Author : Ivor Goodson
Publisher : Routledge
Release : 2016-10-04
File : 875 Pages
ISBN-13 : 9781317665700


Life Histories Of North American Flycatchers Larks Swallows And Their Allies

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This is the fourteenth in a series of bulletins of the United States National Museum on the life histories of North American birds, with previous numbers issued as follows: 107, 113, 121, 126, 130, 135, 142, 146, 162, 167, 170, 174, 176. This bulletin deals with the Order Passeriformes, specifically the Family Cotingidae (Cotingas); Family Tyrannidae (Flycatchers) ; Family Alaudidae (Larks) and Family Hirundinidae (Swallows) of North America

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Genre : Birds
Author : Arthur Cleveland Bent
Publisher :
Release : 1942
File : 996 Pages
ISBN-13 : CHI:72661426


Reproductive Biology And Early Life History Of Fishes In The Ohio River Drainage

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This seven-volume series is the most extensive treatise on early life histories of the freshwater fishes of North America. It represents the state-of-the-art in fishery biology and provides a systematic approach to the study of early life histories of all the fishes in this region. Each volume contains distinguishing characteristics and a pictorial

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Genre : Nature
Author : Robert Wallus
Publisher : CRC Press
Release : 2006-06-02
File : 417 Pages
ISBN-13 : 9781000611434


Encyclopedia Of Evolutionary Biology

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Encyclopedia of Evolutionary Biology, Four Volume Set is the definitive go-to reference in the field of evolutionary biology. It provides a fully comprehensive review of the field in an easy to search structure. Under the collective leadership of fifteen distinguished section editors, it is comprised of articles written by leading experts in the field, providing a full review of the current status of each topic. The articles are up-to-date and fully illustrated with in-text references that allow readers to easily access primary literature. While all entries are authoritative and valuable to those with advanced understanding of evolutionary biology, they are also intended to be accessible to both advanced undergraduate and graduate students. Broad topics include the history of evolutionary biology, population genetics, quantitative genetics; speciation, life history evolution, evolution of sex and mating systems, evolutionary biogeography, evolutionary developmental biology, molecular and genome evolution, coevolution, phylogenetic methods, microbial evolution, diversification of plants and fungi, diversification of animals, and applied evolution. Presents fully comprehensive content, allowing easy access to fundamental information and links to primary research Contains concise articles by leading experts in the field that ensures current coverage of each topic Provides ancillary learning tools like tables, illustrations, and multimedia features to assist with the comprehension process

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Genre : Science
Author :
Publisher : Academic Press
Release : 2016-04-14
File : 2138 Pages
ISBN-13 : 9780128004265


Publications List

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Genre : Biology
Author : U.S. Fish and Wildlife Service. Publications Unit
Publisher :
Release : 1993
File : 52 Pages
ISBN-13 : COLUMBIA:CU15739406


Becoming Bilingual In School And Home In Tibetan Areas Of China Stories Of Struggle

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This book contributes significantly to our understanding of bilingualism and bilingual education as a sociocultural and political process by offering analyses of the stories of five Tibetan individual journeys of becoming bilingual in the Tibetan areas of China at four different points in time from 1950 to the present. The data presented comprises the narrative of their bilingual encounters, including their experiences of using language in their families, in village, and in school. Opportunities to develop bilingualism were intimately linked with historical and political events in the wider layers of experiences, which reveal the complexity of bilingualism. Moreover, their experiences of developing bilingualism are the stories of struggle to become bilingual. They struggle because they want to keep two languages in their lives. It illustrates their relationship with society. They are Tibetans. L1 is not the official language of their country, but it is the tie with their ethnicity. It addresses bilingualism linked with the formation of identity. The unique feature of this book is that it offers a deep understanding of bilingualism and bilingual education by examining the stories of five individuals’ learning experiences over a period of almost 60 years.

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Genre : Education
Author : YiXi LaMuCuo
Publisher : Springer
Release : 2019-07-09
File : 196 Pages
ISBN-13 : 9783030146689


Life Histories Of North American Nuthatches Wrens Thrashers And Their Allies

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Genre : Amphibians
Author : Arthur Cleveland Bent
Publisher :
Release : 1948
File : 716 Pages
ISBN-13 : OSU:32435029592995


Canadian Ethnology Society Papers From The Sixth Annual Congress 1979

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Proceedings of the Sixth Annual Congress of the Canadian Ethnology Society (1979) with contributed papers ranging in topic from semiology to the seventeenth century Iroquois wars to Japanese ghost stories.

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Genre : Social Science
Author : Marie-Françoise Guédon
Publisher : University of Ottawa Press
Release : 1981-01-01
File : 275 Pages
ISBN-13 : 9781772822403