A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.

This book illustrates the importance of microbiome interactions in sustainable agriculture and the environment. The chapters of the book provide information pertaining to the vast diversity of microbiomes in many ecosystems and their functional dynamics. The book also discusses bioremediation, space microbiomes, geo microbiomes, coral microbiomes, antibiotic resistomes, and rhizomicrobiome. It also sheds light on the complex syntrophic and other symbiotic interactions between bacteria, protists, plants, and certain animals in agricultural and environmental systems. The book, in turn, provides an understanding of the adaptation, resilience, and evolution of microbial ecosystems. Further, the chapters cover metagenomics analysis of microbiomes of a novel or extreme environments, microbial resilience or temporal fluctuations, symbiosis and co-evolution of the microbiome, and novel microbial interactions in agriculture and environment. Finally, the book elucidates a comprehensive yet representative description of complex structural and functional diversity within the plant and environmental microbiomes to reveal their immense potential. This book covers United Nations Sustainable Developmental Goal 2 towards Zero Hunger.

In complex systems, such as our body or a plant, the host is living together with thousands of microbes, which support the entire system in function and health. The stability of a microbiome is influenced by environmental changes, introduction of microbes and microbial communities, or other factors. As learned in the past, microbial diversity is the key and low-diverse microbiomes often mirror out-of-control situations or disease. It is now our task to understand the molecular principles behind the complex interaction of microbes in, on and around us in order to optimize and control the function of the microbial community – by changing the environment or the addition of the right microorganisms. This Research Topic focuses on studies (including e.g. original research, perspectives, mini reviews, and opinion papers) that investigate and discuss: 1) The role of the microbiome for the host/environmental system 2) The exchange and change of microbes and microbial communities (interplay) 3) The influence of external factors toward the stability of a microbiome 4) Methods, possibilities and approaches to change and control a system’s microbiome (e.g. in human or plant disease) 5) Experimental systems and approaches in microbiome research. The articles span the areas: human health and disease, animal and plant microbiomes, microbial interplay and control, methodology and the built environment microbiome.

An Introduction to the Microbiome in Health and Diseases covers the compositional structure and roles of the human microbiome in health and disease. Sections discuss and foundational content, from bench to bedside in microbiology to trigger more in-depth knowledge and provide updated findings on today's hottest topic–the microbiome. The book translates current findings of studies into clinical practice. Other sections give updates on the role of microbiome in health and several diseases, the impact of diet, exercise and gut microbiome, the plant microbiome, non-infectious environmental agents and autoimmunity. - Provides fundamental coverage on the microbiome and its effect on human health and diseases. - Describes procedures for sampling small and larger samples of the microbiome. - Discusses patents, bioproducts, commercialization, and the social, ethical and economic implications of the microbiome.

"This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. Resident microbes in healthy animals--including humans--can dictate many traits of the animal host. This animal microbiome is a second immune system conferring protection against pathogens; it can structure host metabolism in animals as diverse as reef corals and hibernating mammals; and it may influence animal behavior, from social recognition to emotional states. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet, and have contributed to animal diversification over long evolutionary timescales"--Publisher by publisher.

This book explores the relationship between the gut microbiome and cancer, illuminating various facets from fundamental roles to personalized therapies. It provides a comprehensive overview of the impact of the gut microbiome on cancer development, offering potential for innovative diagnostic and treatment approaches. The book discusses the role of dysbiosis in cancer development, the influence of the microbiome on treatment responses, and strategies to modulate the microbiome for enhanced therapies. It reviews the influence of the gut microbiome on immunotherapy resistance and chemoresistance in cancer patients. Additionally, the book presents gut microbiome biomarkers for cancer diagnosis and prognosis, the implication of the gut-brain axis on cancer development and progression, and the impact of diet and lifestyle on the microbiome. Towards the end, the book investigates the role of the gut microbiome in pediatric cancer and provides an outlook on the future challenges, technological advancements, and ethical considerations of gut microbiome research in the context of personalized cancer therapies. This book is intended for cancer researchers, medical oncologists, clinicians, pharmacologists, translational investigators, and medical students.