The positive versus negative distinction of schizophrenic disorders has pro moted ongoing research. Phenomenology, psychopathology, biology, genet ics, pharmacological and nonpharmacological treatment, psychosocial and longitudinal research: all have found a new focus of interest. This volume attempts to provide an unbiased picture of the status of American and Eu ropean knowledge regarding the positive/negative distinction. Researchers from North America and Europe describe the relation of modern concepts of positive and negative symptomatology to the original models of Rey nolds and Jackson. Integrating phenomenological, genetic, and biological factors, the authors depict current methods of assessing positive and nega tive symptomatology, differentiating between primary and secondary symp tomatology, and using pharmacological and nonpharmacological treatment. The stability of positive and negative symptoms over time and evidence for the occurrence of separate positive and negative episodes over a long-term course of schizophrenia are extensively discussed in terms of their implica tions on the positive/negative construct. The relevance of the positive/nega tive dichotomy to child and adolescent schizophrenia is also debated. The main aim of this book is not to advocate a single concept and present only arguments supporting it, but to discuss important controversies. Prob lems concerning a concept cannot be solved by ignoring them. However, unanswered questions may be resolved through discussion, debate, and con structive compromise.

This text describes the design and implementation of high-performance feedback controllers for engineering systems. It emphasizes the frequency-domain design and methods based on Bode integrals, loop shaping and nonlinear dynamic compensation. The book also supplies numerous problems with practcal applications, illustrations and plots, together with MATLAB simulation and design examples.

Critical Appraisal of Medical Literature provides a step-by-step approach to help the reader reach a good level of proficiency in systematic critical appraisal of medical information. To this end, the book covers all the elements that are necessary to develop these skills and is a comprehensive guide to the subject. The book is written in three parts. The first part focuses on the logical justification and the validity of medical information. Its chapters present basic working definitions and discussions on relevant basic topics of statistics and epidemiology. The second part focuses on the complementary aspects of critique, common study designs and articles whose main topics are treatment, diagnosis, prognosis, aetiology, reviews, medical guidelines, audit, and qualitative research. The third part presents some statistical techniques that are commonly used in published articles. Critical Appraisal of Medical Literature is intended for those interested in developing critical appraisal skills such as psychiatric trainees preparing for the Critical Review Paper of the MRCPsych Examination in the UK, other practitioners as part of their preparation for examinations, and medical professionals and students as part of their introduction to aspects of systematic critical appraisal of medical information.