This text describes the rapid advances that have revolutionized reproductive medicine due to the result of converging and overlapping developments in reproductive biology, molecular biology and genetics.

As more people turn to assisted reproduction, the legal issues surrounding it have become increasingly complex. Beyond representing patients or clinics, numerous legal problems are arising from the technology's application. Disputes in divorce are the most common, but this technology impacts the law in other areas, including personal injury, insurance, criminal law, and estate planning. Drawing from multiple legal sources, this book presents complex information in a direct, balanced and fair manner. It includes glossary, sample forms and checklists, and bibliography.

VOLUME 1: INFERTILITY SECTION 1: ANATOMY AND PHYSIOLOGY 1. Anatomy of the Reproductive System 2. Regulation and Physiology of Menstrual Cycle 3. Oogenesis and Folliculogenesis 4. Spermatogenesis 5. Fertilization and Embryogenesis 6. Implantation 7. Embryo Endometrial Crosstalk and Endometrial Receptivity SECTION 2: REPRODUCTIVE ENDOCRINOLOGY 8. Synthesis and Metabolism of Steroid Hormones 9. Puberty and Aberrations 10. Amenorrhea 11. Endocrine Disorders Affecting Reproduction 12. Hirsutism 13. Luteal Phase Defect 14. Anovulation 15. Declining Fertility SECTION 3: COMBINED TOPICS 16. Evaluation of Infertility 17. Immunology and Infertility 18. Cytogenetics and Subfertility 19. Obesity and Infertility 20. Unexplained Infertility 21. Fertility Preservation 22. Counseling in Infertility 23. Assisted Reproductive Technology in Patients with Chronic Medical Disorders SECTION 4: MALE INFERTILITY 24. Etiopathogenesis of Male Infertility 25. Clinical and Endocrinological Evaluation of Infertile Male 26. Sexual Dysfunction in Male Infertility 27. Ultrasound in Male Infertility 28. Medical Management of Male Infertility 29. Azoospermia: Evaluation and Management 30. Varicocele and Infertility 31. Spinal Cord Injuries and Male Infertility 32. Algorithms for Genetic Evaluation of Infertile Males SECTION 5: FEMALE FACTOR INFERTILITY 33. Uterine Factors in Infertility 34. Tubal Factors in Infertility 35. Infections and Infertility 36. Tuberculosis and Infertility 37. Sonoendocrinology and Cycle Monitoring Assisted Reproduction Technology 38. Transvaginal Ultrasound and Doppler in Infertility 39. Polycystic Ovary Syndrome 40. Assessment of Ovarian Reserve 41. Endometriosis 42. Endoscopy in Infertility 43. Reconstructive Surgeries Enhancing Fertility SECTION 6: INTRAUTERINE INSEMINATION 44. Intrauterine Insemination 45. Optimizing Success in Intrauterine Insemination SECTION 7: OVARIAN STIMULATION 46. Drugs for Ovarian Stimulation 47. Ovulation Induction and Ovarian Stimulation Protocols 48. Role of Adjuvants in Ovarian Stimulation 49. Gonadotropinreleasing Hormone Analogs 50. Monitoring of Ovarian Stimulation 51. Ovulation Trigger 52. Individualized Controlled Ovarian Stimulation 53. In Vitro Fertilization Lite 54. Role of Luteinizing Hormone in Ovarian Stimulation 55. Anesthesia in Assisted Reproductive Techniques 56. Oocyte Retrieval. 57. Embryo Transfer 58. Troubleshooting in Assisted Reproductive Technology 59. Luteal Phase Support SECTION 8: DILEMMA IN ART 60. Poor Responder 61. Recurrent Implantation Failure 62. Empty Follicle Syndrome 63. Role of Aneuploidy Screening in Preimplantation Embryos 64. Preimplantation Genetic Testing of Embryos 65. Epigenetics and Assisted Reproductive Technology SECTION 9: COMPLICATIONS IN ART 66. Ovarian Hyperstimulation Syndrome 67. Ectopic Pregnancy 68. Multipleorder Births SECTION 10: THIRD PARTY REPRODUCTION 69. Oocyte and Sperm Donation 70. Surrogacy in Assisted Reproductive Technology 71. Assisted Reproductive Technology Guidelines 72. Adoption 73. LGBTQ and Fertility 74. Transgender Population and Fertility SECTION 11: OUTCOME FOLLOWING ASSISTED REPRODUCTIVE TECHNIQUE 75. Maternal and Fetal Outcomes Following Assisted Reproductive Technique 76. Early Pregnancy Scan 77. Recurrent Pregnancy Loss: From Diagnostic Dilemmas to Clinical Decisions SECTION 12: RECENT ADVANCES 78. Bioengineered Human Endometrium In Vitro. 79. Recent Trends in A...

Practical, evidence-based guide to managing ART pregnancies, based on 30 years of clinical experience, including gynaecological, genetic and obstetric complications.

Surgery, Assisted Reproductive Technologies and Infertility describes the intersection of assisted reproductive technologies (ART) and surgery in the diagnosis and treatment of a variety of clinical disorders in reproduction. Unlike many texts currently available, this book provides a road map for management well beyond the how-to for a given problem. It brings you a cogent explanation about the when and why of management. The author balances decision trees and management paradigms with equal weight to surgery and ART as complementary procedures to enhance reproductive potential. He carefully explains options incorporating diagnostic studies into the paradigm that include conventional radiography (eg, hysterosalpingography), two- and three-dimensional ultrasound imaging and MRI analysis. The text includes clear discussion of the rationale for selecting one technique over another and the supporting role for surgery as a prelude to ART or as an appropriate first line management. The text is centered on dividing evaluations in infertility into the tandem topics of structure and function. All chapters include data from studies directed at the assessment of structure using two- or three-dimensional ultrasound and the assessment of function using the technology of the emerging field of functional genomics. The introductory chapters cover embryology and anatomy of the female reproductive tract, evidence-based medicine in reproductive medicine and diagnostic studies that include imaging studies and the emerging field of microarray analysis and the insight gained from this technology. Each clinical chapter describes specific anatomic abnormalities and an approach emphasizing contemporary diagnostics and therapeutics. Every chapter begins with a historical perspective followed by discussions of state-of-the-art diagnostic studies, etiology, surgical management and guidelines for arriving at an outcomes driven decision regarding the intersection of surgery and ART. The discussion is supported by over 300 images and drawings illustrating each abnormality and surgical procedure. All recommendations are data and outcomes based. This approach minimizes anecdotal data, intuition or clinical hearsay. The text emphasizes an evidence-based approach and presents outcomes to support suggested plans of management. The most clinically and cost effective technology is matched to the clinical setting. Bottom line recommendations are written in a clear and concise bullet presentation at the conclusion of each chapter to help you meet the challenge of clinical infertility practice.

Advances in the field of Assisted Reproductive Technology (ART) have been revolutionary. This book focuses on the use of ARTs in the context of families who seek to conceive a matching sibling donor as a source of tissue to treat an existing sick child. Such children have been referred to as 'saviour siblings'. Considering the legal and regulatory frameworks that impact on the accessibility of this technology in Australia and the UK, the work analyses the ethical and moral issues that arise from the use of the technology for this specific purpose. The author claims the only justification for limiting a family's reproductive liberty in this context is where the exercise of reproductive decision-making results in harm to others. It is argued that the harm principle is the underlying feature of legislative action in Western democratic society, and as such, this principle provides the grounds upon which a strong and persuasive argument is made for a less-restrictive regulatory approach in the context of 'saviour siblings'. The book will be of great relevance and interest to academics, researchers, practitioners and policy makers in the fields of law, ethics, philosophy, science and medicine.

In the past half century great progress has been made in the reproductive management of farm animals, both mammals and birds. This book aims to review developments and indicate which reproductive technologies can be used commercially or in research. It begins by discussing artificial insemination and how this has recently been refined in semen sexing technology. Embryo transfer, in vitro embryo production technology and the control of oestrus and ovulation are then reviewed. Subsequent chapters consider the control of postpartum ovarian activity, seasonal breeding, multiple births and litter size, pregnancy testing, parturition, and the onset of puberty. The author then describes more recent developments in cloning and the production of transgenic animals, before a final chapter on suppressing reproductive activity.

Textbook of Assisted Reproductive Technologies is a truly comprehensive manual for the whole team at the IVF clinic. Information is presented in a highly visual manner, allowing both methods and protocols to be consulted easily. The text provides clinical and scientific teams with the A to Zs of setting up an embryology laboratory, gives research fellows insight into technical developments, and supplies seasoned professionals with a review of the latest techniques and advances. New to the Third Edition: fully revised and expanded chapters, with new information on: single embryo transfer artificial gametes pharmacogenetics

Delivers current knowledge from global experts at the forefront of fertility and ART healthcare The first publication of its kind, this book on fertility and assisted reproductive technology (ART) is a globally focused, authoritative guide to state-of-the-art information about modern fertility and ART healthcare. Written for clinicians, public health officials, women’s health experts, scientists, students, scholars, and other interested individuals, the book encompasses theoretical, research, policy, and clinical practice aspects of fertility and ART healthcare. The book features the diverse contributions of multidisciplinary researchers, scholars, and clinicians from eight countries who explore contemporary health care perspectives regarding individuals and families dealing with infertility and fertility challenges including such advanced technologies as in-vitro fertilization, intrauterine insemination, and oocyte preservation. The book addresses theoretical underpinnings of fertility and ART healthcare including new ways of conceptualizing research and theoretical concepts. Practical aspects involved with administering and treating the many women and men whose lives are affected by fertility challenges are illuminated. Complex policy concerns resulting from the rapid advances in fertility and ART are considered. The health care needs of those seeking fertility evaluation and treatment including access to care locally and globally are examined in depth. The book also includes discussions about novel approaches and emerging populations in fertility and ART healthcare that expand the scope of care. Thought-provoking case examples from contemporary care practices will help the reader to synthesize information. Key Features: Delivers thought provoking ART research and practice issues for health care clinicians, scholars, and scientists Synthesizes evolving theory, research, clinical practice, and public policy concerns Addresses complex considerations within the practice and delivery of fertility and ART services Written by international thought leaders and emerging scholars on the forefront of ART technologies and other issues Includes case study exemplars to stimulate critical thinking and transform discussion about modern fertility and ART care

This book deals with all recent advances in clinical and laboratory aspects of assisted reproductive therapy (ART). It elaborates on innovations and developments in the field that have the potential to improve ART outcomes. Chapters cover such topics as newer techniques for evaluating sperm, DNA, and ovarian reserve, including proteomic analysis, sonoendocrinology, preparation and administration of platelet-rich plasma, and in vitro maturation. Authors also address the structure, function, and role of low molecular weight ligands of gonadotropins, as well as the ethical and legal aspects of ART.