Colorectal cancer (CRC) represents a major public health problem worldwide. Fortunately most CRCs originate from a precursor lesion, the adenoma, which is accessible and removable. This is the rationale for CRC screening programs, which are aimed to diagnose CRC at an early stage or even better to detect and resect the advanced adenoma before CRC has developed. In this background colonoscopy emerges as the main tool to achieve these goals with recent evidence supporting its role in CRC prevention. This book deals with several topics to be faced when implementing a CRC screening program. The interested reader will learn about the rationale and challenges of implementing such a program, the management of the detected lesions, the prevention of complications of colonoscopy, and finally the use of other screening modalities that are emerging as valuable alternatives. The relevance of the topics covered in it and the updated evidence included by the authors turn this book into a very useful tool to introduce the reader in this amazing and evolving field.

Henshaw (psychiatry, University of Keele, UK) and Elliott (consultant clinical psychologist, St Thomas' Hospital, UK) provide guidance for health care professionals on the controversies surrounding screening for perinatal depression and on good practice in the use of screening tools. International contributors, with backgrounds in psychiatry, psychology, medicine, nursing, midwifery, and social work, discuss the advantages and drawbacks of the available screening methods, and investigate women's perceptions of the usefulness of screening. Ethnic minority experiences and screening programs in developing countries are also considered.' - Book News 'The book considers a variety of issues and identifies agreement in ideas and continuing debates. Whether the reader is concerned with women's views of screening, the role of the midwife, screening in the US, Australia or developing countries, screening of women with serious mental illness, Black Caribbean women's views of screening, health visitor intuition and much more, there is something here for them. Each chapter, often drawing on the author's own work, stands on its own. Tutors, researchers, practitioners and students should be able to use the relevant parts to challenge their thinking, reflect on their practice and ask yet more questions about this significant subject.' - Community Practitioner Screening for perinatal depression is now widely undertaken in the UK and Europe and is attracting increasing attention. This much-needed text provides guidance for health care professionals on the issues and controversies surrounding screening and on good practice in the use of screening tests. An international author team with backgrounds in psychiatry, psychology, medicine and nursing has been brought together to discuss the available screening methods, their advantages and drawbacks. The authors investigate women's perceptions of the accessibility and usefulness of screening and of the roles of professionals (e.g. primary care staff and health visitors), and also look at ethnic minority women's experiences of health services. The role of the UK National Screening Committee is explored, along with the problems faced when implementing screening programmes in developing countries. This comprehensive and practical book will enable mental health professionals, social workers and health visitors to provide sensitive and informed services to women at risk of perinatal depression.

High throughput screening remains a key part of early stage drug and tool compound discovery, and methods and technologies have seen many fundamental improvements and innovations over the past 20 years. This comprehensive book provides a historical survey of the field up to the current state-of-the-art. In addition to the specific methods, this book also considers cultural and organizational questions that represent opportunities for future success. Following thought-provoking foreword and introduction from Professor Stuart Schreiber and the editors, chapters from leading experts across academia and industry cover initial considerations for screening, methods appropriate for different goals in small molecule discovery, newer technologies that provide alternative approaches to traditional miniaturization procedures, and practical aspects such as cost and resourcing. Within the context of their historical development, authors explain common pitfalls and their solutions. This book will serve as both a practical reference and a thoughtful guide to the philosophy underlying technological change in such a fast-moving area for postgraduates and researchers in academia and industry, particularly in the areas of chemical biology, pharmacology, structural biology and assay development.

"[the authors] did a masterful job of creating and editing this gold standard book that should be used by all clinicians and incorporated into all nursing and health sciences curriculums." -Bernadette Mazurek Melnyk, PhD, APRN-CNP, FNAP, FAANP, FAAN Vice President for Health Promotion University Chief Wellness Officer Dean and Helene Fuld Health Trust Professor of Evidence-Based Practice, College of Nursing Professor of Pediatrics & Psychiatry, College of Medicine Executive Director, the Helene Fuld Health Trust National Institute for EBP The Ohio State University This is the only book to explicitly guide clinicians through an evidence-based approach to ordering and interpreting laboratory tests. With over 160 commonly ordered tests, this book is designed to foster more accurate clinical decision-making to attain the highest level of patient care. This book summarizes more than 3000 pieces of evidence and incorporates clinical expertise and decision-making on the ordering and interpretation of tests. To promote ease of use, a convenient table maps labs and their corresponding chapter numbers to the relevant body system to promote ease of use. Each laboratory test is presented in a consistent format with information on physiology, indications (screening, diagnosis, and monitoring), algorithms, test interpretation and follow-up testing, patient education, and related diagnoses. Additional valuable features include clinical pearls that highlight common pitfalls and gaps in reasoning, and a cost-benefit analysis. This book also includes CPT and ICD-10 codes, charts and tables for clarification, and references for further study. Key Features: Delivers a strong, evidence-based approach to ordering and interpreting over 160 laboratory tests Promotes accurate clinical decision-making toward achieving the Triple Aim Includes abundant clinical pearls highlighting common pitfalls and gaps in reasoning Provides cost-benefit analysis and discussion of laboratory testing within a high-value healthcare culture Includes 175 supplemental case examples and 200 self-assessment questions to facilitate instruction and learning Includes more than 3000 pieces of evidence from interprofessional resources