Sex Differences in the Brain

Within the basic and clinical biomedical research community, there is increasing recognition that differences between males and females across the lifespan affect an individual's health, his/her development of disease, signs and symptoms of pathophysiology, and response to therapy. This book is intended as a resource for scientists, clinicians, and students of the nervous system and behavior- a trove of practical information about how to study sex differences in the brain as well as a discussion of what is already known on the topic.

Draws on the latest findings beyond cultural perceptions to reveal how the brain processes love and interpersonal relationships, addressing such questions as the practicality of monogamy, and whether or not the "seven-year itch" actually exists.

Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. - Explores sex differences in human neuroanatomy and neurophysiology - Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders - Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context

Sex/Gender presents a relatively new way to think about how biological difference can be produced over time in response to different environmental and social experiences. This book gives a clearly written explanation of the biological and cultural underpinnings of gender. Anne Fausto-Sterling provides an introduction to the biochemistry, neurobiology, and social construction of gender with expertise and humor in a style accessible to a wide variety of readers. In addition to the basics, Sex/Gender ponders the moral, ethical, social and political side to this inescapable subject. An interview with the author! WOMR - The Lowdown with Ira Wood - Sex an Gender Identity with Anne Fausto-Sterling: http://www.publicbroadcasting.net/womr/.jukebox?action=viewMedia&mediaId=1025429

Sex and gender in biomedicine are innovative research concepts of theoretical and clinical medicine that enable a better understanding of health and disease, evidence-based knowledge, effective therapies, and better health outcomes for women and men. Gender Medicine stimulates new ways of doing research: that is to consider sex and gender at all levels of research, from basic research into gene polymorphisms to health behaviour. New research questions have been put forward that focus not on differences per se but on the development of differences. In this book, contributions from the field of neuroscience, addiction research, and organ transplantation exemplify concepts, approaches, methods and results in the field.

As the papers in this special issue demonstrate, gonadal hormones have powerful effects on the development of the brain and behavior in human beings, as in other species. Both androgens and estrogens affect behavior throughout development, from early prenatal life through adulthood, as demonstrated in studies with a variety of methods in several species. The articles also describe attempts to identify the mechanisms--neural and basic behavioral--that mediate hormonal effects on complex human behaviors. This issue testifies to the breadth and vitality of research into the ways that hormones affect the development of sex-typical behavior, and illustrates several important themes that have emerged in human psychoneuroendocrinology. First, it is now clear that hormones do affect human behavior, and the important questions relate to the mechanisms and details of hormone action. Second, there are many ways to study hormone effects on human behavior, and this issue describes these methods and their products. Third, traditional conceptions of hormone-behavior relations have generally stood the test of time, but recent developments have begun to reveal the complexity of these relations. Taken as a whole, the articles in this special issue are interesting and worthwhile reading in their own right, but they may also act to stimulate developmental neuropsychologists to consider hormones in their own studies.

Focusing on the novels of Charlotte Bronte, Wilkie Collins, and Thomas Hardy, Malane analyzes how these narratives of love, insanity, and tragedy were in dynamic conversation with the prevailing views about the brain."--Jacket.

Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine. - Covers the most important developments in biomedical research in the past decade, with a thoughtful analysis of how they impact patient care - Discusses the feasibility and usefulness of personalized medicine, the limits and promise of genetic editing, the basis for variation in sexual identity and how artificial intelligence and technology will affect basic human function as well as correcting disability - Promotes and facilitates discussions about the ethics and governance issues that surround much of what science is now able to do at the most basic levels of human's physiology

Does gender, sex and sexuality influence children's play, and their learning? Can/should professionals try to influence children's gender and sexual concepts? Can/should professionals try to prevent gender stereotyping? These and other questions are explored in a lively and thought-provoking text that looks at why and how children inhabit or develop their gender and sexuality. Written in an approachable way and illustrated with case studies and linked to current research and theory, the book helps students, teachers and playworkers understand the debates about biology versus culture and social learning and how these impact on children's expression of gender and sexuality. Engaging the reader in a thorough reflection of their own views and approaches to the genderized and sexualized behaviour of children at play, this text is an invaluable guide for all those interested in the importance of play, gender and sexuality and how they relate to children's lives. Topics include: play and the behaviour of boys and girls within particular social contexts; play and girls' and boys' sexual behaviour and their associated feelings; play and children's self-concepts and expectations; the professional adult workers' role and the manifestation of genderized and/or sexualized play behaviour both in and outside a setting.