The classification of tumors is important for understanding tumor histogenesis, for predicting prognosis, for differential diagnosis, and for recommending appropriate therapy. Since 1836, when pancreatic cancer was first described, progress has been made in pancreatic cancer morphology, and a number of classifications have been proposed. All of these classifications are mainly based on morphological characteristics. Some are too detailed to be of practical use while others are more pragmatic. Some of the inherent problems in the previous classifications included difficulties in obtaining an adequate number of pan creatic tumors for examination and insufficient clinical data and follow-up. With the increasing incidence of pancreatic cancer in many parts of the world during the past six decades, and with the availability of more tumors to patho logists, advances have been made in pancreatic tumor studies. Classifications by Cubilla and Fitzgerald and by Kloppel, which are generally similar, mostly considered prominent morphological features and their histogenesis. These pathology-oriented classifications, although complete, were not practical from the standpoint of clinicians concerned with the prognosis of individual tumors.

For a long time, approximately since Oberlin and Guerin described the multifocal origin of pancreatic cancers and precancerous pancreatic lesions, no important study dealing with the entire subject of pancreatic cancer has been published in France and probably in the international literature. For some decades the knowl edge acquired 40years or more ago was not improved appreciably, though the fre quency ofthe disease started to increase in occidental countries. This has recently changed, and the progress ofthe medical sciences has spread to the pancreas. Although the surgical or medical prognosis of the most frequent form of pancreatic cancer, exocrine adenocarcinoma, remains very bad, recent studies have shown the multiplicityofits pathological forms, some being less severe so that curative surgery is possible. New experimental models, particularly in the hamster, and the use of carcinogenic drugs allow experimental studies on lesions similar to those in man. Oncologic immunology is still at its beginnings but shows promise for diagnosis and treatment. Though modem techniques of imaging sonography, aspirative cytology, CT scan, endoscopic catheterism, arteriography, and maybe in the future nuclear magnetic resonance - have not yet significantly in fluenced prognosis, they have made the diagnosis easierand more precocious. Yet in a diseasethat diffuses so rapidly to deep lymph nodes, it has not been proved whether early diagnosis can improve prognosis.

The MD Anderson Solid Tumor Oncology series presents cutting-edge surgical treatment and medical therapy for specific sites. This volume, Pancreatic Cancer, addresses epidemiology and molecular biology, inherited syndromes, staging, surgical techniques, multimodality therapy, and emerging therapies. The individual chapters focus on narrow, specific topics to produce a reference work of value to those interested in pancreatic cancer from a clinical and translational research perspective. A must-have for surgical oncologists and general surgeons.

The Oxford American Handbook of Clinical Medicine Second Edition covers all areas of internal medicine and surgery, offering up-to-date advice on examination, diagnostic testing, common procedures, and in-patient care. Students, residents, nurses, and clinicians will find the handbook to be a succinct, comprehensive, and affordable introduction to clinical medicine in the popular format of the Oxford American Handbooks in Medicine series. The second edition includes a thorough updating of diagnostic and therapeutic guidelines, updated information on key clinical trials, numerous new images, and new information on palliative care. This handbook has everything you need for on-the-spot access to evidence-based clinical management guidelines.

In 74 chapters, Gastrointestinal Oncology brings together a diverse group of specialists to provide the most authoritative, up-to-date and encyclopedic volume currently available on the subject. The first part of this text introduces a series of concepts and topics taht are important to gastrointestinal malignancies in general. These topics include epidemiologic principles, prevention, screening, familial GI cancers, developmental and molecular biology, pathobiology, general therapeutic principles, emerging therapies, and palliative care. The second part of the book covers each of the specific cancers affecting the human gastrointestinal tract. These chapters are introduced by state of the art discussions outlining our current understanding of the pathobiology and molecular biology relevant to each cancer. Subsequent sections describe the multidisciplinary management of specific clinical situations. By organizing the treatment-related chapters around clinical scenarios, the reader will readily find the information necessary to effectively manage the complex clinical situations encountered by patients with gastrointestinal malignancies.

As a single comprehensive reference source and full-color atlas, this book covers a wide range of pathology. Normal anatomy as well as developmental abnormalities are detailed. A variety of non-neoplastic conditions are covered, including transplant pathology, diabetes mellitus and pancreatitis. Neoplasms are emphasized. The difficulties encountered with frozen section diagnosis, cytopathology, and tumor classification systems are addressed. Common and rare conditions of pancreas, gallbladder, extrahepatic biliary tract and ampullary regions are all extensively reviewed. Special attention is paid to clinical features, prognostic factors, biologic behavior and survival. With almost 1,300 color images and over 5,300 references, this treatise is a major contribution to field.

Diagnose tumors with confidence with Diagnostic Histopathology of Tumors, 4th Edition. Dr. Christopher Fletcher's renowned reference provides the advanced, expert guidance you need to evaluate and interpret even the most challenging histopathology specimens more quickly and accurately. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Diagnose efficiently and effectively using diagnostic flow charts, correlations of gross appearances to microscopic findings, and differential diagnosis tables for better recognition and evaluation of similar-looking entities. Employ immunohistochemistry, molecular and genetic diagnostic tests, and other modern techniques as well as the best morphologic diagnostic methods to effectively identify each tumor or tumor-like entity. Utilize new, clinically important molecular genetic data and updated classification schemes to help guide treatment and targeted therapy. Apply the latest techniques and diagnostic criteria with completely rewritten chapters on Small and Large Intestines, Heart, Larynx and Trachea, Ear, and Peritoneum. Find critical information quickly thanks to more tables and bulleted lists throughout.

Learn to effectively recognize, diagnose, and treat common internal medical conditions with this invaluable reference. Small Animal Internal Medicine, Fourth Edition, emphasizes practical diagnostic approaches and focuses on the clinically relevant aspects of patient medical management. Extensive color illustrations, boxes, and algorithms, plus new photographs, schematic representations, and updated tables, set this book apart. With its highly functional design and clear, expert voice, this text delivers the most relevant information for the internal medical challenges you’re most likely to face. Utilizes a problem-oriented approach, beginning with a discussion of clinical signs and diagnostic recommendations and techniques and moving on to therapeutic considerations and management Each contributor is a recognized expert in his or her respective specialty. Limited number of authors provides consistency. Clear, step-by-step procedural guidelines thoroughly describe each procedure. Cross-referencing throughout the book reduces redundancy and makes information easy to locate. Suggested readings at the end of each chapter alert you to the latest research findings. Comprehensive drug tables provide recommended dosages and indications. Purposefully written to enhance critical thinking and decision-making skills based on clinical findings. Hundreds of summary boxes and tables allow quick access to clinical signs, etiology, differential diagnoses, drugs, and treatment. Full-color format brings you accurate visual depictions of specific disorders, diseases, and procedures. Two new section editors bring a fresh perspective. Discussion of Immune-Mediated Disorders has been significantly expanded and made into its own section. Hundreds of new, full-color photographs and quick reference tables throughout Completely updated drug and treatment guidelines tables

This highly readable textbook provides a comprehensive but concise overview of the principles of oncogenesis in veterinary medicine, discussing selected tumors in domestic animals in detail, and addressing cancer diagnostics and therapy. All chapters are illustrated with histological and radiological images to enhance readers’ understanding. Accordingly, the book is a must-have reference guide for all graduate and advanced undergraduate students in Veterinary Medicine with a special interest in oncology.