Dedicated to dealing with a challenging disease, previously thought to be incurable, but with the advent of new drugs, now amenable to management and a much improved prognosis for patients. - Latest publication in a fast-moving area of keen clinical interest - Authored by leading international authorities - Builds on success of a respected first edition - Incorporates new data on latest imaging technologies and therapies - Covers both the science and clinical aspects, including presentation, surgical intervention and drug therapy - Includes coverage of both Pulmonary Embolism and Deep Vein Thrombosis

Cerebral veins contain about 70% of the total cerebral blood volume, but cerebral venous thrombosis (CVT) occurs about a thousand times less often than arterial stroke. CVT affects mostly young adults and children, and in about one quarter of cases the cause remains unknown. Written by international experts, this publication is dealing with epidemiology, risk factors, coagulation disorders, clinical presentation - especially focusing on headache, current neuroradiological treatment, complications and long-term prognosis of CVT. The book covers the full spectrum of CVT pathogenesis and offers a new and effective approach to improve earlier diagnosis, recognize new risk factors and to identify the most severe manifestations, which require more aggressive treatments. Neurologists, interventional neuroradiologists, neurosurgeons, and all physicians who are involved in the care of patients with CVT will welcome this publication as a useful and up-to-date clinical guide.

Now in its Third Edition, this authoritative text continues to provide a comprehensive and systematic review of the biology, pathobiology, and clinical disorders of the hemostatic system. Its unique organization of the basic sciences coupled with clinical sections yields a user-friendly integrated text, and a reference tool that meets the needs of diverse investigators and clinicians of contemporary medicine for understanding the hemostatic system. New chapter topics covered in this edition include angiogenesis and vasculogenesis; hemorrhagic complications of antithrombotic therapy; interactions of coagulation and fibrinolytic proteins with the vessel wall; and less common thrombotic disorders.

Monthly, with annual cumulation. Recurring bibliography from MEDLARS data base. Index medicus format. Entries arranged under subject, review, and author sections. Subject, author indexes.

The pre-eminent reference on coagulation disorders is now in its thoroughly updated Fifth Edition. Written by more than 160 of the world's foremost authorities, this encyclopedic volume integrates basic science and clinical practice and details all that is currently known about blood clotting disorders and how to manage patients with these and related problems. This edition has been reorganized into smaller, more tightly focused chapters to help readers find information easily. A new co-editor, Samuel Z. Goldhaber, MD, has expanded the cardiology portion of the book. Other new features include a two-color page design and more than 100 full-color illustrations.

A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.

2014 BMA Medical Book Awards Highly Commended in Internal Medicine category! A unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today's newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout. Access the entire text and illustrations online - fully searchable - at www.expertconsult.com.

Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside provides a detailed understanding of the endothelium, its activation and their link to some common clinical disorders. In addition, the book covers earlier discoveries, including those from the last and 19th centuries. It is split into five sections that cover the vascular tree as an integrative structure, the endothelium in inflammation, endothelial signaling, activation and toxicity with chemotherapy, radiation induced endothelial dysfunction and vascular disease, and therapies in combating vascular diseases. Each section is discussed with a translational approach in order to make the content truly applicable. This book is a valuable source for basic researchers, clinicians in the fields of Oncology, Cardiovascular Medicine and Radiology, and members of the biomedical field who are conducting studies related to the endothelium and vascular disease. - Discusses the most relevant discoveries in endothelial biology and their link to manifestations of clinical disease - Presents history and diagrams in each section to highlight the original biological discovery and its link of clinical manifestations of vascular disease - Includes recent findings on the relationship between endothelial signaling, chemotherapy and radiation induced endothelial dysfunction

Emergency vascular and endovascular practice comprises almost half the workload undertaken by the majority of vascular surgeons. Most vascular emergencies are characterised by the sudden occlusion, rupture or injury of a blood vessel placing organ, limb and life at risk. An attitude of urgency and of good judgement, both in diagnostic assessment and the application of evidence-based vascular and endovascular techniques, is crucial to the achievement of optimal outcomes. This book is structured with the emphasis on clinical presentation, the objective being to provide accessible and highly practical advice to the vascular surgeon faced with a particular emergency. Distinguished vascular surgeons, vascular radiologists and other specialists around the world have enriched this book with authoritative contributions reflecting their experience and expertise. For ease of reference the text is divided into nine sections, leading with introductory chapters on general considerations such as pathophysiology, preoperative diagnosis, risk assessment and medico-legal aspects of vascular emergencies. That is followed by a series of clinical sections covering acute cerebrovascular syndromes, acute limb ischaemic states, the acutely swollen limb, thoraco-abdominal catastrophes, acute complications of endovascular aortic repair, regional vascular trauma and iatrogenic injuries. It concludes with a section on miscellaneous, but important, acute vascular challenges. Throughout the book, wherever appropriate, modern endovascular techniques are given full coverage. International in its approach, this book will fast become established as the text devoted to the surgical management of vascular and endovascular emergencies. It is essential reading for vascular surgeons and radiologists and a useful reference source for general and trauma surgeons, angiologists and emergency physicians.

Published in association with the Society for Vascular Surgery, Rutherford’s Vascular Surgery presents state-of-the-art updates on all aspects of vascular health care. Extensively revised by many new authors to meet the needs of surgeons, interventionalists, and vascular medicine specialists, this medical reference book incorporates medical, endovascular and surgical treatment, as well as diagnostic techniques, decision making and fundamental vascular biology. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Master the latest developments, techniques, and approaches with thorough updates on endovascular applications, vascular access, imaging, non-operative management, and much more. View clinical and physical findings and operative techniques more vividly with a full-color layout and images. Get answers you can depend on. Rutherford's delivers the world’s most trusted information on all major areas of vascular health care, is written by international experts, and includes up-to-date bibliographies and annotated recommended references. Discover emerging techniques in rapidly advancing topics, with special emphasis on endovascular coverage, vascular imaging, angiography, CT and MRI. Explore brand new chapters on dialysis catheters, renovascular disease, and management of branches during endovascular aneurysm. Stay up-to-date with the latest coverage of endovascular procedures that reflects the changing practices and techniques in vascular surgery. Access videos at Expert Consult.