PET and SPECT are two of today's most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world's fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging.*Contains thorough tutorial treatments, coupled with coverage of advanced topics*Three of the four holders of the prestigious Institute of Electrical and Electronics Engineers Medical Imaging Scientist Award are chapter contributors*Include color artwork

This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.

Gamma ray detection techniques for radioisotope imaging purposes are quickly evolving. Monte Carlo simulations show the possibility of achieving an outstanding image spatial resolution in the images obtained with techniques using electronic collimation. The great advantage of using electronic collimation is the increased efficiency of the gamma camera with respect to the usage of the mechanical collimation technique. These new imaging techniques require radiation detectors with very specific features, such as low noise, desired stooping power and compactness. In this thesis project, an apparatus for detection of a Compton deposition of gamma rays, capable of differentiating the position of interaction of the gamma ray in the active volume of the detector, has been developed. The design and manufacture of such an apparatus implies the selection and characterization of the radiation sensitive material and its calibration, as well as its associated electronics, in order to achieve the critical requirements to be used as part of the electronic collimated gamma camera. Along with the detector development, the electronic collimation requires a very specific control system. The required logic system that makes possible the usage of the apparatus as part of the the electronic collimation set-up, has also been developed as part of this thesis work. This electronic system is meant to work in coordination with other sensors, and its final output is to give exact information of the photon-electron interaction points, in order for an image to be deduced. The result of this thesis work is a radiation detector ready to be used as the tracker component in the application of the electronic collimation technique. Its control system allows it to be used to build a Compton camera by simply removing the mechanical collimator of a regular gamma-camera, and arranging both detectors in the desired radioisotope imaging electronic collimation scenario.

The congress’s unique structure represents the two dimensions of technology and medicine: 13 themes on science and medical technologies intersect with five challenging main topics of medicine to create a maximum of synergy and integration of aspects on research, development and application. Each of the congress themes was chaired by two leading experts. The themes address specific topics of medicine and technology that provide multiple and excellent opportunities for exchanges.

The cutting-edge new edition of the classic introduction to radioactive measurement Gammy-Ray Spectrometry is a key technique in the study of radioactive decay. It measures the rate and extent of radioactivity from a variety of sources, both natural and artificial, including cosmic ray sources, nuclear reactors, high-energy physics experiments, and more. The resulting data can be essential to environmental monitoring and to a range of experimental sciences. For years, Practical Gamma-Ray Spectrometry has served as the classic introduction to this area for current or aspiring practitioners. A comprehensive but accessible treatment of the subject, with a thorough discussion of all major classes of detectors and their associated electronic systems, it contains everything a researcher needs to make optimal gamma-ray measurements. Now fully updated to reflect the latest technology and experimental data, it is a must-own for researchers looking to incorporate gamma-ray spectrometry into their scientific practice. Readers of the third edition of Practical Gamma-Ray Spectrometry will also find: Fault-finding guide for rapid and effective problem resolution Workshop-style approach emphasizing the fundamentals of laboratory practice New sections dealing with novel developments in nuclear structure research, measuring effects of pollution and climate change, new semiconductor materials, and more Practical Gamma-Ray Spectrometry is ideal for PhD students and practicing gamma-ray spectroscopists, including researchers working on radiation, energy and environmental monitoring professionals, and researchers working in physics, archaeometry, and related subjects.

A generalized Radon transform (GRT) maps a function to its weighted integrals along a family of curves or surfaces. Such operators appear in mathematical models of various imaging modalities. The GRTs integrating along smooth curves and surfaces (lines, planes, circles, spheres, amongst others) have been studied at great lengths for decades, but relatively little attention has been paid to transforms integrating along non-smooth trajectories. Recently, an interesting new class of GRTs emerged at the forefront of research in integral geometry. The two common features of these transforms are the presence of a 'vertex' in their paths of integration (broken rays, cones, and stars) and their relation to imaging techniques based on physics of scattered particles (Compton camera imaging, single scattering tomography, etc).This book covers the relevant imaging modalities, their mathematical models, and the related GRTs. The discussion of the latter comprises a thorough exploration of their known mathematical properties, including injectivity, inversion, range description and microlocal analysis. The mathematical background required for reading most of the book is at the level of an advanced undergraduate student, which should make its content attractive for a large audience of specialists interested in imaging. Mathematicians may appreciate certain parts of the theory that are particularly elegant with connections to functional analysis, PDEs and algebraic geometry.

This book will provide readers with a good overview of some of the most recent advances in the field of detector technology for gamma-ray imaging, especially as it pertains to new applications. There will be a good mixture of general chapters in both technology and applications in medical imaging and industrial testing. The book will have an in-depth review of the research topics from world-leading specialists in the field. The conversion of the gamma-ray signal into analog/digital value will be covered in some chapters. Some would also provide a review of CMOS chips for gamma-ray image sensors.

Radiation Detectors for Medical Imaging discusses the current state of the art and future prospects of photon-counting detectors for medical imaging applications. Featuring contributions from leading experts and pioneers in their respective fields, this book:Describes x-ray spectral imaging detectors based on cadmium zinc telluride (CdZnTe) and cad