In 1956 Tjio and Levan first identified the human diploid chromosome number to be 46. This was later confirmed by Ford and Hemerton in the same year. Then the human male complement was found to be 46, XY and female complement 46,XX. The first chromosomal abnormality, that is the presence of 47 chromosomes in Down's syndrome was reported by Lejeune et al. (1959).

In this issue of MRI Clinics, guest editors Drs. Erica B. Stein and Kim L. Shampain bring their considerable expertise to MR Imaging of the Adnexa. Top experts in the field cover key topics such as MR imaging of ovaries: from puberty to menopause; MR imaging of Müllerian anomalies; MR imaging of epithelial ovarian neoplasms; MR imaging of germ cell and sex-cord stromal neoplasms; and more. - Contains 12 relevant, practice-oriented topics including MR imaging of endometriosis; MR imaging of mimics of adnexal pathology; MR imaging of the adnexa: technique and image acquisition; MR of fallopian tubes; MR imaging of acute adnexal pathology; and more. - Provides in-depth clinical reviews on MR imaging of the adnexa, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Fertility preservation in children has long only been considered for those facing gonadotoxic treatments in the setting of new diagnoses of cancer. However, this field is now being expanded to include children with other conditions affecting fertility such as rheumatologic/nephrologic disease and even the transgender population, where fertility preservation counseling and discussion is in its infancy. Research regarding the optimal methods, timing, and eventual outcomes of both ovarian and testicular tissue storage in prepubertal girls and boys, respectively, as well as data on outcomes of oocyte and semen cryopreservation in adolescence is lacking. Deriving mainly from literature in adults, ovarian tissue cryopreservation has recently been deemed non-experimental; knowledge gaps still exist in the pediatric population.

Case-based investigations, management, and treatment of pediatric and adolescent gynecological conditions, based on up-to-date evidence.

This volume comprehensively focuses on amenorrhea, one of the most important diseases in gynecology, affecting women from puberty to menopause. Amenorrhea is analyzed from its etiologies, pathogenesis, consequences and treatments throughout puberty, food and cycle disorders, exercise and stress impact, fertility- and sexual-related affection, and menopause transition. Written by experts in the field, this book will be of benefits to residents, general practitioners and specialists, gynecologists and endocrinologists, who deal with women’s health care.

**Selected for Doody's Core Titles® 2024 in Clinical Genetics** Human Reproductive and Prenatal Genetics, Second Edition provides application-driven coverage of key topics in human reproductive and prenatal genetics, including genetic control underlying the development of the reproductive tracts and gametogenesis, the genetics of fertilization and implantation, the genetic basis of female and male infertility, as well as genetic and epigenetic aspects of assisted reproduction. Also examined are the genetics and epigenetics of the placenta in normal and abnormal pregnancy, preimplantation genetic diagnosis and screening, and cutting-edge advances in noninvasive prenatal screening, prenatal genetic counseling, and bioethical and medicolegal aspects of relevance in the lab and clinic. This new edition has been fully revised to address new and evolving technologies in human reproductive genetics, with new chapters added on chromatin landscapes and sex determination, genetic alterations of placental development and preeclampsia, metabolism and inflammation in PCOS, pre-implantational genetic testing, maternal genetic disorders, bioethics, and future applications. - Features chapter contributions from leading international scientists and clinicians - Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization, placental development, embryo implantation, in vitro culture of the human embryo for the study of post-implantation development, and more - Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics-based approaches - Includes all new chapters on evolving technologies and recent genetic discoveries of relevance to reproductive medicine

Amenorrhea: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Amenorrhea in a compact format. The editors have built Amenorrhea: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Amenorrhea in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Amenorrhea: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.