Dr. Felice has put together clinical reviews articles that cover a broad scope of clinical issues that are common among sexually active adolescent patients. Some issues addressed include: HPV Vaccine Update; Treating Dysmenorrhea/Menorrhagia; New STD Guidelines; Emergency Contraception; Talking to Parents about Teen Sexuality; and Long-acting Reversible Contraception. Most pediatricians feel poorly equipped to address these problems. They are also complicated issues that give the average pediatric clinician pause and often take more time than usually scheduled in a busy practice. By providing practical updated information on these clinical problems, pediatric practitioners can become more comfortable in dealing with these topics. Although many clinicians are not involved with adolescents in the juvenile justice system, Dr. Felice included an article on this so that pediatricians can be more educated and sensitive to the needs of these young people. An article on human trafficking of teens in included with the hope bringing awareness of this issue. Articles in this issue were selected specifically because they directly affect primary pediatric care. For example, an article is included on how to help young people avoid being victims of partner violence rather than an article on sexual abuse and rape because adolescents would be treated in the emergency room and not the pediatrician’s office.

Dr. Kliegman and Dr. Bordini have written a primer on Undiagnosed and Rare Diseases in Children. Leading experts have presented the current knowledge in the following areas: How Doctor’s Think: Common Diagnostic Errors in Clinical Judgment; Team-Based Approach to Undiagnosed and Rare Diseases; Ending a Diagnostic Odyssey: Family Education Counselling and Their Response to Eventual Diagnosis; Eczema and Urticaria as Manifestations of Undiagnosed and Rare Diseases; Usual and Unusual Manifestations of Familial Hemophagocytic and Langerhans Cell Histiocytosis Syndromes; When Autistic Behavior Suggests a Disease Other than Classic Autism; Non-classic Inflammatory Bowel Disease in Young Infants; IPEX and Other Disorders; Usual and Unusual Presentation of Mitochondrial Disorders; When to Suspect Auto-inflammatory/Recurrent Fever Syndromes; Primary and Secondary Causes of Autonomic Dysfunction; Usual and Unusual Manifestations of Systemic and CNS Vasculitis; Fever of Unknown Origin; Differentiating Familial Neuropathies from Guillain-Barre Syndrome; and Munchausen by Proxy: A Factitious Undiagnosed Disease. Readers will come away with cutting-edge information to use immediately in their clinical management of patients.

Pediatricians care for children and families from all walks of life. Some are children known from neighborhoods. Others are children from distant lands. Pediatric focus does not stop with the physical care of children but extends to include their mental and social-emotional health and concern about their families. Pediatricians care about how children are doing at home, at school, and in their communities. In this era, children and their families are impacted by social and political changes in their homes (social media and screen time), in their communities (refugee populations and children requiring palliative supports at school), in their health care networks (EMR in every tertiary pediatric center), and in the larger world (multiple military deployments of fathers and mothers). This issue explores the impact of contemporary public health challenges for pediatric care, promising models for caring for chronically ill children, and state of the art therapies for complex childhood conditions.

The Guest Editors have tapped top key opinion leaders to provide current reviews on the clinical diagnosis and treatment of gastrointestinal disease in children. They have focused on topics related to GERD; Celiac Disease and Gluten Sensitivity; IBD; Motility Disorders; GI Bleeding and Management; Pancreatic Disorders; Hepatitis B and C; Liver Transplant; Abdominal Pain; Complications from Obesity; and Neonatal Cholestasis.These articles will provide a state-of-the-art overview of diagnosis and treatment of GI diseases that are impactful for the general pediatrician.

In this issue of Pediatric Clinics of North America, guest editors Drs. Xiaoming Li and Sayward Harrison bring their considerable expertise to the topic of Progress in Behavioral Health Interventions for Children and Adolescents. Nearly three-quarters of adult mental health disorders have their onset during childhood, where treatment becomes more difficult and has greater social, educational, and economic consequences over time. This issue provides the information and resources needed to identify and treat mental health and clinical issues in children, with the goal of improving outcomes. - Contains 16 relevant, practice-oriented topics including leveraging technology in novel interventions for autism spectrum disorder; childhood obesity prevention and treatment; parental rules, parental routines, and children's (0-12 years) sleep and screen time; family-based preventions and interventions for child emotional and behavioral functioning in families facing stress/trauma; integrating behavioral health in primary care; and more. - Provides in-depth clinical reviews on behavioral health interventions for children and adolescents, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

The Guest Editors of this issue have come together with the goal of producing a useful, basic guide on this population for pediatric primary care clinicians. Topics in this issue address: Caring for LGBT Youth & Families in Inclusive and Affirmative Environments; Mental Health and the Development of Sexual Orientation and Gender in Children and Adolescents; What the Primary care Pediatrician Needs to Know about Gender Variance in Children and Adolescents; Clinical Implications of Stigma, Minority Stress, and Resilience as Predictors of Health and Mental Health Outcomes; LGBT Youth and Bullying; LGBT Youth and Family Acceptance; HIV, Other Sexually Transmitted Infections, and Sexual Health in LGBT Youth; Substance Abuse Prevention, Assessment & Treatment for LGBT Youth; Body Image and Disordered Eating among LGBT Youth; and Sociocultural Factors and LGBT Youth’s Health-related behavior. Pediatricians will come away with a solid understanding of recognizing and communicating with LGBT children and adolescents.

In this issue of Pediatric Clinics of North America, guest editors Drs. Robert S. Kahn, Monica Mitchell, and Tina L. Cheng bring their considerable expertise to the topic of Achieving Child Health Equity. Health equity requires removing obstacles to health such as poverty, discrimination, and their consequences, including powerlessness and lack of access to good jobs with fair pay, quality education and housing, safe environments, and health care. In this issue, top experts provide up-to-date information to healthcare practitioners with the goal of implementing programs and policies to identify and address health care inequality for children. - Contains 15 practice-oriented topics including clarity on disparity of healthcare in pediatrics: who, what, when, where and how; screening and addressing social determinants of health in pediatric practice; addressing structural racism in pediatric practice; addressing health literacy in pediatric practice; LGBTQ+ and child health equity; and more. - Provides in-depth clinical reviews of achieving child health equity, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

The topics in this issue represent the most current research areas of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Collaborative Pediatric Critical Care Research Network (CPCCRN). The CPCCRN is a national pediatric critical care research network that is charged with investigating the efficacy of treatment and management strategies to care for critically ill and injured children, as well as to better understand the pathophysiological basis of critical illness and injury in childhood. The proposed authors are past and present principal and co-investigators affiliated with the CPCCRN; the proposed topics represent the individual author’s area of clinical and research expertise. Each review article is an up-to-date review of the topic relevant to practicing clinicians and trainees in critical care medicine, with incorporation of the most recently published research findings pertinent to the topic, some of which may be the author’s own. The specific articles are devoted to the following topics: Cardiopulmonary resuscitation in pediatric and cardiac ICU; Approach to the critically ill pediatric trauma patient; Transfusion Decision Making in Pediatric Critical Illness; Pathophysiology and management of ARDS in children; Ventilator associate pneumonias in critically ill children; Mechanical ventilation and decision support in pediatric intensive care; Inflammation, pathobiology, phenotypes and sepsis: From meningococcemia to H1N1-MRSA, to Ebola; Immune paralysis in pediatric critical care; Molecular biology of critical illness; Sedation in pediatric critical illness; Delirium in pediatric critical illness; Challenges of drug development in pediatric intensive care; Potential of All Steroid Hormone Subclasses as Adjunctive Treatment for Sepsis; Morbidity: Changing the outcome paradigm; and End-of-Life and Bereavement Care in Pediatric Intensive Care Units.

All too often adolescents are neglected by the medical specialists -- there are disciplines devoted to neonates, children, and of course the elderly-but adolescents have special needs during a time of rapid physical, sexual and emotional development. This book addresses these issues, highlights the specific diseases of adolescents, and will be invaluable to anyone with an interest in adolescent medicine.

In this issue of Pediatric Clinics of North America, guest editors Drs. Roger W. Apple and Ethel G. Clemente bring their considerable expertise to the topic of Role of Psychologists in Pediatric Subspecialties. Top experts in the field highlight the interdisciplinary nature of primary care of children where psychology is a factor, placing emphasis the clinical topics, disease states, or medical specialties where mental health has a significant impact on the outcome and successful treatment of clinical issues in children. This issue offers a unique focus on collaboration between the psychologist and pediatrician to optimize outcomes. - Contains 16 practice-oriented topics including helping physicians collaborate with psychologists; psychologists' experiences in pediatric hematology-oncology; the role of psychologists in child abuse pediatrics; the critical role of psychologists in pediatric gastroenterology; the role of psychologists in pediatric sports medicine practice; and more. - Provides in-depth clinical reviews on the role of psychologists in pediatric subspecialties, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.