Viral infections in animals occasionally develop potentially fatal diseases that affect almost all organs. Especially in zoonotic diseases, the causative agents that usually exist in animals can be transmitted between animal species to humans directly or via a vector. Throughout recent history, disease outbreaks and pandemics including SARS, H7N9, Ebola, and COVID-19, have led to a dramatic loss of human life worldwide and harmed economic growth. The most effective strategies for the control of disease are vaccination and early diagnosis. Vaccines directed against viral and bacterial pathogens prevent catastrophic losses of life in humans, other animals, and plants, and are considered among the greatest public health achievements. Rapid and accurate detection of pathogens and identification of the aetiologic agent play a crucial role at every step of disease management. In the case of zoonotic illnesses, early detection of wildlife aids in the establishment of a surveillance system, allowing for the introduction of efficient and timely disease control interventions to prevent transmission from animal to human. At present, variations and deletions in the genome of the virus are of common occurrence during evolution, coupled with the new emerging disease and cross-species disease transmission, which are increasing the potential for the transmissibility and severity of the disease. For this reason, developing safe and effective vaccines, and enhancing the sensitivity and specificity of the diagnostic methods are urgently required. The scope of this research topic will share and discuss findings in the areas of diagnosis of viral diseases or vaccine development for all animal species, including terrestrial and aquatic mammals, fishes, insects, birds, etc.

Advances in Animal Disease Diagnosis: Infectious animal diseases caused by pathogenic microorganisms such as bacteria, fungi, and viruses threaten the health and well-being of wildlife, livestock and human populations, limit productivity and significantly increase economic losses to each sector. Pathogen de-tection is an important step for the diagnosis and successful treatment of animal diseases as well as control management in farm and field conditions. The conventional techniques employed to diagnose pathogens in livestock species are time-consuming and sometimes give inconclusive results. On the contrary, molecular techniques have the potential to diag-nose known pathogens/conditions quickly, reliably, and unequivocally as well as for novel pathogen detection. New advances in diagnostics and vaccine design using genomics have developed powerful new methods that have also set the stage for the enhanced diagnosis, surveillance, and control of infectious diseases. High-throughput sequencing (HTS), for ex-ample, uses the latest DNA sequencing platforms in the detection, identification, and detailed analysis of both pathogen and host genomes. This book will explore some key opportunities in the context of animal health, such as the detection of new microorganisms and the development of improved diagnosis of emerging or re-emerging diseases and other clinical conditions, viz. biosensors, nanotools, and omics technologies. Features • Details comprehensive knowledge on the latest molecular techniques for animal disease diagnosis and management • Examines how DNA-based diagnostic techniques will assist international efforts to control the introduction of exotic diseases into new geographic areas • Describes the latest molecular assays for the rapid and accurate detection of pathogens • Helps in working towards meeting the global challenge for sustainable food production and the eradication of poverty • With new biotechnological developments, this fully updated book is a treasure trove of the latest information in animal and medical science

There has been a continual expansion in aquaculture, such that total production is fast approaching that of wild-caught fisheries. Yet the expansion is marred by continued problems of disease. New pathogens emerge, and others become associated with new conditions. Some of these pathogens become well established, and develop into major killers of aquatic species. Diagnosis and Control of Diseases of Fish and Shellfish focuses on the diagnosis and control of diseases of fish and shellfish, notably those affecting aquaculture. Divided into 12 chapters, the book discusses the range of bacterial, viral and parasitic pathogens, their trends, emerging problems, and the relative significance to aquaculture. Developments in diagnostics and disease management, including the widespread use of serological and molecular methods, are presented. Application/dose and mode of action of prebiotics, probiotics and medicinal plant products used to control disease are examined, as well as the management and hygiene precautions that can be taken to prevent/control the spread of disease. This book will be a valuable resource for researchers, students, diagnosticians, veterinarians, fish pathologists and microbiologists concerned with the management of diseases of fish and shellfish.

We are now entering the third decade of the 21st Century, and, especially in the last years, the achievements made by scientists in the field of Microbiology have been exceptional, leading to major advancements. Frontiers has organized a series of Research Topics to highlight the latest advancements in science in order to be at the forefront of science in different fields of research. This specific editorial initiative, led by Dr. Axel Cloeckaert is focused on new insights, novel developments, current challenges, latest discoveries, recent advances and future perspectives in the field. The Research Topic solicits brief, forward-looking contributions from the editorial board members that describe the state of the art, outlining recent developments and major achieved accomplishments, future challenges and how to address those challenges to move the field forward. Reviews, Mini-Reviews, Perspectives, and Opinions summarizing the current state and future directions of the field are particularly welcome in this collection.

Advances in Virus Research, Volume 115, the latest release in this comprehensive serial that highlights new advances in the field, includes updates on a variety of timely topics, including Plant viral nanotools, Mycoviruses, Rift Valley Fever virus entry and infection, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Advances in Virus Research series

We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS

Pigs are important agricultural animals with ancient domestication history and economic value and have become important sources of protein for humans. Infectious diseases affect the health of pigs and the stability and productivity of the global swine industry. The emergence and reemergence of several contagious swine diseases in recent years have posed a severe threat to pig production globally. Increasing concern has been raised about the immunosuppressive effect caused by immunosuppressive swine pathogens in recent years, such as porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus (PCV), African swine fever virus (ASFV), classical swine fever virus (CSFV), pseudorabies virus (PRV) among others. Infection with variant strains of PRRSV, PRV, and the low virulence strains of ASFV increase the pathogenicity of opportunistic infectious agents, causing secondary disease challenges, which can result in more complicated clinical symptoms and severe diseases. These diseases lead to increased treatment expenses, reduced swine herd growth rate, and feed conversion rate. However, with the ongoing viral evolution and the emergence of novel variants, current research into the mechanisms underlying immunosuppression remains inadequate, highlighting the urgent need for further investigation.

Evolving Landscape of Molecular Diagnostics: Applications and Techniques presents cutting-edge reviews on current and emerging technologies in the diagnosis of microbial infections. The book discusses the fundamentals of Molecular Diagnostics for bacteria, fungi, viruses and a variety of state-of-the-art diagnostics tools and techniques for obtaining qualitative and quantitative results. It includes topics such as Next generation sequencing and application of "OMICS" for early disease diagnosis. Sections cover the entire spectrum of emerging diagnostic tools and techniques, as well as the principles, pros and cons of each method and applications for diagnosis of infectious disease in plants, humans and veterinary. This is a resource for both researchers and students working in clinical microbiology, infectious biology, applied life sciences and scientists working in the clinical diagnostic industry. - Provides a wide range of diagnostics tools and technologies in the field of infectious biology - Presents discussions on emerging technologies for early disease diagnosis and novel diagnostics techniques for detection of COVID, Urea Breath Tests for Detection of Helicobacter pylori, Loop-Mediated Isothermal Amplification as Point-of-Care Diagnosis, Molecular imaging, Lab-on-a-chip Technologies, and several others - Analyzes literature reviews, underpinning methodologies, and opportunities and limitations - Includes case studies and examples that highlight applications using the underpinning techniques

After the experience of the first volume, The World Association for Animal Production (WAAP) continues the publication of the Book of the Year series for the benefit of animal scientists and policy makers in the field of livestock systems. The WAAP asked the best known and significant animal scientists in the world to contribute to the preparation of this book. Following the success of the first volume of the series, the WAAP Book of the Year 2003, many authors from the six continents are contributing to this 2nd volume. The importance of this publication is to have already established a worldwide reference for the animal science and production sectors. There are the usual four sections that raised much interest in the previous volume of the series. The first section has six articles, describing the changing conditions of livestock systems in each of the six continents. The second section has more than twenty papers, describing the development of the many sectors in which the animal science field has been divided. The third section, dealing with contemporary issues, is declared by our readers to be the most interesting. It allows participating authors to describe current and significant issues important in these last years for the animal science and production sectors. The statistics produced in the previous volume are updated and enhanced with new figures in this book to form the fourth section. The papers included in this book speak clearly of the development in the last twelve months in the livestock systems worldwide. Major space is also devoted to the list of references from where every author can start to deepen his knowledge. This book is essential for libraries that want their readers to be easily updated. Also scientists, policy makers and scientific writers, who need, to enhance their competence, to have the most practical way of knowing what is going on in the world in the field of livestock science and production will find this book of great value.