Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. Contributions from leading authorities and industry experts Informs and updates on all the latest developments in the field

Rare diseases are a group of genetic disorders occurring in a small percentage of the population with the conditions being chronic but incurable. Approximately 7000 to 8000 different types have been identified and about 350 million people globally are affected in childhood and adulthood, resulting in enormous physical, mental, and psychological suffering and financial burden. It is imperative for medical scientists, clinicians, communities, and societies to ensure appropriate care is applied to ease the suffering of such patients. The extraordinary and unprecedented hallmark in the field of rare diseases has revolutionized modern human medicine with exciting and advancing developments of the genomic era over the last two decades. Patients with rare diseases have been receiving increasing benefits in care and life quality improvements than ever before. This book intends to share and exchange the advancing knowledge and experiences from the authors, who have the necessary expertise within the various topics and subjects in the research, diagnosis, and management of rare diseases. It is hoped they are able to provide further benefits to patients and families with the development of early and accurate diagnosis and effective therapies.

Stiehm's Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. - Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians - Fills an increasingly deep gap in the information available to clinicians - Presents both clinical management and scientific advances for immune deficiencies - Provides a primary resource for physicians in the field of immunodeficiencies - Includes website access to a range of videos relevant to the topics discussed

Now in a fully updated edition, this essential text explores the other half of Europe—the new and future members of the European Union along with the problems and potential they bring to the region and to the world stage. Clear and comprehensive, it offers an authoritative and up-to-date analysis of the transformations and realities in Central and Eastern Europe, the Baltics, and Ukraine. Divided into two parts, the book presents a set of comparative country case studies as well as thematic chapters on key issues, including EU and NATO expansion, the economic transition and its social ramifications, the role of women, persistent problems of ethnicity and nationalism, and political reform. Leading scholars provide the historical context for the current situation of each country in the region. They explain how communism ended and how democratic politics has emerged or is struggling to emerge in its wake, how individual countries have transformed their economies, how their populations have been affected by rapid and wrenching change, and how foreign policy making has evolved. New to this edition are chapters on social issues and transitional justice. For students and specialists alike, this book will be an invaluable resource on the newly democratizing states of Europe.

Why anyone can turn their love for beekeeping into more than a satisfying hobby (including a business in your backyard) Are you looking for a way to reconnect with nature in this stressful world? Have you been thinking of finding a unique, fascinating hobby, or a new way of income? Do the news of the decline in bees’ populations terrify you? If you answered “yes” to any of those questions, then beekeeping is just the perfect match for you. The shelves of grocery stores are filled with overly processed, sweet liquid that can’t really be called “honey”. With your own little apiary, you can have direct access to top-quality honey and bee products, all of which have astonishing health benefits. Furthermore, you can help save the planet. Bees have been around for 100 million years, but recently their populations have decreased rapidly: ⚫by 40% in the US since 2006 ⚫by 25% in Europe since 1985 ⚫by 45% in the UK since 2010 The Food and Agriculture Organization predicts that if the trend continues, by 2035 the common honeybee might disappear. Why not aid the issue by taking care of a couple of colonies? Even though it might sound intimidating at first, starting your journey into beekeeping can go smoothly and quickly. This book will provide you with the knowledge you need to launch a sustainable, healthy bee sanctuary...and turn it into a successful business if you want to. Follow the footsteps of start like Scarlett Johansson, Morgan Freeman, Bruce Springsteen, Leonardo DiCaprio, and Michelle Obama and become a treasured carer for those precious pollinators, even without any previous experience. Thanks to “Advanced Beekeeping”, you will discover: ⚫The full spectrum of bee products and their unique health benefits ⚫8 simple tips to raising your bees in the most natural way ⚫Answers to 10 most common questions about biodynamic beekeeping, and how to implement it in 6 easy steps ⚫Tools and techniques for providing your bees with the best housing there is ⚫How to provide a healthy, stress-free environment for bees with the help of nature ⚫How to keep your bee colonies happy and safe without interfering with their natural strategies ⚫Secrets of preparing simple and effective medicines and cosmetics using everything your little friends will have to offer ⚫8 proven steps that will help you start earning money from beekeeping And much more. But wait, you may think, I don’t have a sprawling ranch for all the hives. Don’t worry – you don’t need one. You can easily and safely have a couple of beehives in your backyard, on your roof or on your balcony. Beekeeping is not just for those with swathes of land and hundreds of colonies. Whether you want some premium quality bee products for yourself, or you want to turn it into a small business, this book will help you get a jumpstart into beekeeping. With everything from the very basics to creating a goldmine of a business plan, this book is a must-have for you if you too are dreaming of starting your very own apiary. You too can feel the buzz of excitement when you join the ranks of the planet’s heroes. Just click “Add to cart” above and start your beekeeping adventure.

Encephalitis means "inflammation of the brain," but it usually refers to brain inflammation caused by a virus. This severe and potentially life-threatening disease is rare. Encephalitis takes two forms, categorised by the two ways that viruses can infect the brain: Primary encephalitis. This occurs when a virus directly invades the brain and spinal cord. It can happen to people at any time of the year (sporadic encephalitis), or it can be part of an outbreak (epidemic encephalitis).* Secondary (post-infectious) encephalitis. This form occurs when a virus first infects another part of the body and secondarily enters the brain. The primary form of the disease is more serious, while the secondary form is more common. This new volume presents important research from around the globe.

First published in 1969, European Advanced Technology expounds a programme of action for Europe to tackle the challenge posed by American technology in the 1960s. It analyses first the nature of the American predominance in science and technology and goes onto describe the efforts of the major European states to counter it on their own. It then explains the limitations of these efforts at the level of the nation state and shows how European countries have gone on to work together in certain key sectors: high energy physics, nuclear power, aircraft, space, electronics, transport and communications. The history of these programmes is examined carefully and the book describes a wider strategy. It deals with larger questions like how Europe can develop a common science and technology policy; what should be done to promote industrial integration and European companies, and what individual companies and the British government can and should do? This book will be an essential read for scholars and researchers interested in the history of European Union, European history, international organisations and European Politics.

There is no field of medicine in which advances in therapy have been so closely linked to a better understanding of molecular medicine than in the area of hematologic malignancies. Diagnostic and Therapeutic Advances in Hematologic Malignancies will provide practitioners and academic clinicians with a better understanding of the constant evolving concepts in this area.