Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

The recent breakthrough in microbial studies has applied next-generation sequencing (NGS), a massive omics analysis, to the composition and structure of microbial communities. NGS can identify microbes without the need for their cultivation. Their mere presence can be ascertained and often quantitated, and even their metabolic capabilities of microbial constituents predicted. This breakthrough led to an explosive growth in research on microbes. Many important advances have been made in human health-related studies. Indeed, gut microbial communities have been extensively analyzed and differences between healthy and diseased microbiomes have been determined. Studies of the effects of changes of diet, of antibiotic treatments, and of probiotics have been published. Specific attention has been devoted to human pathogens, their mechanisms of causing disease, and the potentials for their management and treatment. Microbiome studies of natural habitats, terrestrial and aquatic, have also benefited from NGS methodology. Increased understanding of the microbial communities has led to the use microbes as antagonists of pathogens, i.e. as treatments. Moreover, novel uses of microbes in industrial processes, either for synthesis of important compounds or for degradation and handling of waste, are being devised. In this volume, chapters dealing with the cutting-edge research in all these fields are presented.

Integrating complementary treatment options with traditional veterinary practice is a growing trend in veterinary medicine. Veterinarians and clients alike have an interest in expanding treatment options to include alternative approaches such as Western and Chinese Herbal Medicine, Acupuncture, Nano-Pharmacology, Homotoxicology, and Therapeutic Nutrition along with conventional medicine. Integrating Complementary Medicine into Veterinary Practice introduces and familiarizes veterinarians with the terminology and procedures of these complementary treatment modalities in a traditional clinical format that facilitates the easy integration of these methods into established veterinary practices.

While veterinary medicine has always valued the concepts and methods of epidemiology, they are virtually inseparable in today’s clinical practice. With access to an ever-expanding number of journals, as well as countless Internet sources, more and more veterinarians are practicing evidence-based medicine. This is defined as the process of systematically finding, appraising, and adopting research findings as the primary basis for clinical decisions. “An underlying premise of the book is that patient-based research is epidemiologic research....It logically follows that the users of this information, veterinary students and practitioners, be skilled in its application to patient care.” – from the preface Veterinary Clinical Epidemiology, Third Edition focuses on developing a deeper understanding of epidemiology and exemplifies how an improved capacity for interpreting and critiquing available literature ultimately leads to improved patient care. In preparing this edition, Ronald Smith, a highly respected epidemiologist, practitioner, and educator, has entirely updated his earlier work to reflect those changes that have dramatically altered the practice of veterinary medicine over the last ten years. New to the third edition: · Numerous updated examples of the application of epidemiology in clinical practice · Expanded journal representation to include a larger selection of international research · Increased coverage of hypothesis testing, survey design, sampling and epidemiologic conceptsrelated to the practice of evidence-based medicine · Revised and updated information on diagnostic testing, risk assessment, causality, and the use of statistics Veterinary Clinical Epidemiology, Third Edition provides practitioners and researchers with the knowledge and tools to understand, critically assess, and make use of the medical literature that is vital to the treatment of animal patients.

Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human - Organ Systems - Molecular Pathology/Basic Mechanisms of Diseases - Animal Models/Other Model Systems - Experimental Pathology - Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. - Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting - Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images - Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions