This book offers comprehensive coverage of all manifestations of resistance in combating infectious diseases and explores advances in antimicrobials in agriculture and their applications in the fight against microbes. According to the World Health Organization, antimicrobial resistance is a major threat to global health because the number of alternative antibiotics is very limited. Antimicrobial resistance is a slow, evolutionary process that has been accelerated by human activities in the health, environment, and agriculture sectors. Due to their wide application, antibiotics and their residues have been found in almost all food products and natural ecosystems. This book appraises the drivers, impact, and mitigation of antimicrobials, with a focus on methods and targets. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. The novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. The underlying molecular mechanisms, which depend not only on the microbe but on the specific drug molecule, are highly diverse and are covered in detail. Students, researchers, scientists, practitioners, academicians, biologists, microbiologists, stakeholders, and policymakers can benefit from current trends in antimicrobials in agriculture that address microbiology, microbial biotechnology, ethnopharmacology, toxicology, natural medicinal plant products, secondary metabolites, and all disciplines related to antimicrobial research. Features of the book: Covers antimicrobials in agriculture with up-to-date research Recent references on plausible antimicrobials in agriculture Public health impact of the use of antibiotics in agriculture Antimicrobial efficacy of medicinal plants Role of phytoalexins in agriculture Nanoparticles as antimicrobial agents Presents cutting-edge research on microbiology, nanotechnology, and emergent antimicrobial technologies

Antimicrobial Resistance in Agriculture: Perspective, Policy and Mitigation is a valuable industrial resource that addresses complex, multi-factorial topics regarding farm, wild, companion animals, fish, and how the environment plays an important role in amplification and transmission of resistant bugs into the human food chain. Information of phenotypical and genotypical properties of each bacterial genus associated with antimicrobial resistance, transmission dynamics from different reservoirs (food animals, poultry, fishes) and control measures with alternative therapy, such as phytobiotics and nanomaterials are provided. Researchers, scientists and practitioners will find this an essential resource on the judicial use of antibiotics in animals and humans. - Explores all the genera of livestock and fish originated pathogenic bacteria associated with antimicrobial resistance - Presents cutting-edge research on epigenetics, nanotechnology and intervention technologies - Discusses transmission dynamics of resistance gene pools from different reservoirs, including food animals, poultry, fishes and the environment

This book offers comprehensive coverage of all manifestations of resistance in combating infectious diseases and explores advances in antimicrobial resistance in agriculture and their applications in the fight against microbes. It discusses and compares biological, biochemical, and structural aspects of resistance and its evolution. This is a comprehensive tool covering all manifestations of antimicrobial resistance and microbial resistance genes. In addition, it also provides a variety of photographs, diagrams, and tables to help illustrate the material. Novel strategies to combat antimicrobial resistance are also described, emphasizing collaborative measures of control. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target) molecule, are highly diverse and are covered in great detail. Students, researchers, scientists, practitioners, academics, computational biologists, stakeholders, and policymakers can benefit from using Antimicrobial Resistance in Agriculture and its Consequences as a resource that addresses microbial biotechnology, microbiology, ethnopharmacology, toxicology, medicinal plant products, and all disciplines related to antimicrobial research. Features of the book: Covers antimicrobial resistance in agriculture with up-to-date research Includes recent references on each plausible antimicrobial resistance in agriculture Details the possible spread of antibiotic resistance bacteria from animals to humans Provides several perspectives in the resistance flux with modern agricultural practices Describes the public health impact of the use of antibiotics in agriculture Presents cutting-edge research on epigenetics, nanotechnology, and emergent antimicrobial technologies Outlines recent laws and regulatory guidelines in the federal agency, responsibility, and authority

Antimicrobial resistance (AMR) is a major health threat to humans, animals, plants and the environment. One of the key drivers of AMR is the misuse and overuse of antimicrobials in animal production, including in aquaculture. Therefore, monitoring the use of antimicrobials in farm animals is essential to mitigate AMR. The World Organisation for Animal Health (WOAH, founded as OIE) has been collecting data, mainly coming from national sales and imports records of antimicrobials, from its members on antimicrobial agents intended for use in animals since 2015. To complement this information and improve decision-making, farm-level antimicrobial use (AMU) data are needed, as it allows for better understanding of how antimicrobials are used in the field. Therefore, the Food and Agriculture Organization of the United Nations Regional Office for Asia and the Pacific (FAO RAP), the WOAH Regional Representation for Asia and the Pacific (WOAH RRAP) and the WOAH Sub-Regional Representation for South-East Asia (WOAH SRR-SEA) developed a joint guideline on Monitoring antimicrobial use at the farm level. The guideline provides detailed guidance on establishing a farm-level AMU monitoring system: conducting a situational analysis; establishing an operational mechanism; technical preparation. The recommendations cover both terrestrial and aquatic food-producing animals and consider the wide range of AMU monitoring capacities in Asia and the Pacific and beyond. The target users of this guideline are the competent authorities, research institutions and agrifood industry actors who plan to develop or improve an AMU monitoring system at the farm level.