It is now widely accepted that cells have the ability to initiate a program of gene-directed death, a process called "apoptosis" which may also be used as an innovative strategy for therapeutic intervention in cancer therapy. Experts in this area report on the regulation and control of apoptosis in hormone dependent (neoplastic) tissue and the possibility to exploit active cell death for therapeutic application.

Cancer is a group of different diseases (more than 100) characterised by uncontrolled growth and spread of abnormal cells. Cancer can arise in many sites and behave differently depending on its organ of origin. If a cancer spreads (metastasizes), the new tumour bears the same name as the original (primary) tumour. Significant progress has been made in recent years in the battle against cancer and in understanding its underlying biological mechanisms. This research progress has resulted in many experimental treatments and cures which establish hope for wide-spread cures. This book brings together important research from around the world in this frontal field.

Issues in Cancer Epidemiology and Research / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Oncology Research. The editors have built Issues in Cancer Epidemiology and Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Oncology Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Cancer Epidemiology and Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Prostate Cancer provides an up-to-date review of the biochemistry, molecular biology, and genetic changes in prostate cells that are the driving forces in the initiation and progression of cancer. It includes an overview by experts in the field of cell-cell interactions, including stem cells, reactive Stromal cells and membrane lipid rafts that are instrumental in the initiation and progression of prostate cancer.

Apoptosis plays a central role in the regulation of cell proliferation. Disruption of this control mechanism may cause serious human diseases such as encephalomyelitis and cancer. Thus, understanding of the molecular mechanisms of apoptotic cell death should lead to fundamental advances in the therapy of these diseases.

The nanotheranostics sector provides a very promising strategy for monitoring drug biodistribution and pathology longitudinal processes by integrating the imaging and drug delivery functions in one single nanoformulation, providing vital insights into the identification of tumour and predicting the efficacy of nanomedicine. For its unique properties, which include their small size and biocompatibility and ability to permeate the cellular membrane with carrying drugs, nanomaterials have been used for various biomedical applications. This book covers the progress made in hormone-related cancer and their management by nonmedicinal therapy for targeting the hormone regulated cancer with their clinical progress and clinical hurdles.

The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.

Novel drugs are being developed which interact with the programmed cell death (apoptotic) machinery in cancer cells, thereby causing these cells to commit suicide and to be removed from the body. Research is also directed to investigate why the cancer cells sometimes lose the ability to undergo apoptosis after a certain period of time and methods are being developed to reactivate this cell death process. This book is intended for workers in the field and clinicians as a useful guide of the state of affairs in this exciting field which may offer more effective possibilities for treatment of cancer patients. Mels Sluyser is the Editor of the journals APOPTOSIS and ANTI-CANCER DRUGS. He brings together a collection of papers written by the world’s leading experts in these fields.

This book is an introduction to cancer treatment, the basics of radio- and chemotherapy, drug actions, the eradication of cancer cells, and the origins and persistence of pharmacological and toxicological effects of drugs. It further provides ideas for research based on knowledge of cancer metastasis, invasive and molecular pathways, and diagnosis and treatment. Many of the adaptive features of cancer biology, clinical features, pathology and treatment are reviewed. In addition to introducing the major themes and theories, the book also advances the current discussion by moving beyond explanations for clinical implementation. Key Selling Features: Reviews basic cancer treatments Summarizes chemotherapies Discusses radiotherapies Examines pharmacological and toxicological approaches to treatment Introduces oncological drug development

Targeting the key active elements in the mechanism and application of apoptosis and its therapeutic implications, Apoptosis: Modern Insights into Disease from Molecules to Man covers apoptosis from A to Z. Comprehensive in scope, it explores a wide range of topics including various cancers, asthma, and multiple sclerosis as well as alcohol induced