A UNIQUE PRACTICE-ORIENTED INTRODUCTION TO PHYSICAL PHARMACY Applied Physical Pharmacy explores the fundamental physicochemical properties and processes important for understanding how drugs are transformed into usable and stable drug products that release their drug upon administration, and for understanding the different processes that the released drug may encounter on its way to its pharmacological target prior to being eliminated by the body. Applied Physical Pharmacy begins with a review of key biopharmaceutics concepts of drug liberation, absorption, distribution, metabolism, and excretion. These concepts, which describe the fate of the drug in the body, set the framework for subsequent chapters that describe physicochemical properties and processes such as states of matter, solutions, ionization, dissolution and partitioning, mass transport, complexation, and protein binding. Concepts in these chapters are important for not only understanding a drug's fate in the body, but also for providing a scientific basis for rational drug formulation and usage. Other physical pharmacy topics important to drug formulation are discussed in the chapters that follow, which describe dispersed systems, rheology, and interfacial phenomena. The book concludes with an overview of the principles of kinetics that are essential to understanding the rates at which many of the processes discussed in previous chapters occur. To facilitate learning, chapters are enhanced by Learning Objectives, Key Points, Problems, and Clinical Questions. To make the book as relevant to real-world practice as possible, this edition includes an increased number of clinical examples and applications.

Designed as the core textbook for the required physical pharmacy or pharmaceutics course within the pharmacy school curriculum. With a focus on examples from pharmacy practice, this book presents the chemical and physical chemical principles fundamental to the development of medication dosage forms. Numerous case studies present relevant examples of physical chemical principles in current pharmacy practice.

Offering the comprehensive, authoritative information needed for effective diagnosis, treatment, and management of sick and premature infants, Fetal and Neonatal Physiology, 6th Edition, is an invaluable resource for board review, clinical rounds, scientific research, and day-to-day practice. This trusted two-volume text synthesizes recent advances in the field into definitive guidance for today’s busy practitioner, focusing on the basic science needed for exam preparation and key information required for full-time practice. It stands alone as the most complete text available in this complex and fast-changing field, yet is easy to use for everyday application. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Contains new chapters on Pathophysiology of Genetic Neonatal Disease, Genetic Variants and Neonatal Disease, and Developmental Biology of Lung Stem Cells, as well as significantly revised chapters on Cellular Mechanisms of Neonatal Brain Injury, Neuroprotective Therapeutic Hypothermia, Enteric Nervous System Development and Gastrointestinal Motility, and Physiology of Twin-Twin Transfusion. Features 1,000 full-color diagrams, graphs and anatomic illustrations, 170+ chapters, and more than 350 global contributors. Includes chapters devoted to clinical correlation that help explain the implications of fetal and neonatal physiology, as well as clinical applications boxes throughout. Provides summary boxes at the end of each chapter and extensive cross-referencing between chapters for quick reference and review. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more.

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Pharmaceutics: Basic Principles and Application to Pharmacy Practice, Second Edition is a valuable textbook covering the role and application of pharmaceutics within pharmacy practice. This updated resource is geared toward meeting and incorporating the current curricular guidelines on pharmaceutics and laboratory skills mandated by the American Council for Pharmacy Education. It includes a number of student-friendly features, including chapter objectives and summaries, practical examples, case studies, numerous images and key-concept text boxes. Two new chapters are included, as well as a new end of chapter section covering "critical reflections and practice applications". Divided into three sections – Physical Principles and Properties of Pharmaceutics; Practical Aspects of Pharmaceutics; and Biological Applications of Pharmaceutics – this new edition covers all aspects of pharmaceutics and providing a single and compelling source for students. Facilitates an integrated and extensive coverage of the study of pharmaceutics due to the clear and engaging language used by the authors Includes chapter objectives and summaries to illustrate and reinforce key ideas Meets curricular guidelines for pharmaceutics and laboratory skills mandated by the Accreditation Council for Pharmacy Education (ACPE) Includes new practice questions, answers, and case studies for experiential learning

Fetal & Neonatal Physiology provides neonatologist fellows and physicians with the essential information they need to effectively diagnose, treat, and manage sick and premature infants. Fully comprehensive, this resource continues to serve as an excellent reference tool, focusing on the basic science needed for exam preparation and the key information required for full-time practice. The 5th edition is the most substantially updated and revised edition ever. In the 5 years since the last edition published, there have been thousands of publications on various aspects of development of health and disease; Fetal and Neonatal Physiology synthesizes this knowledge into definitive guidance for today's busy practitioner. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Chapters devoted to clinical correlation help explain the implications of fetal and neonatal physiology. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. Features a fantastic new 4-color design with 1,000 illustrations, 170+ chapters, and over 350 contributors. 16 new chapters cover such hot topics as Epigenetics; Placental Function in Intrauterine Growth Restriction; Regulation of Pulmonary Circulation; The Developing Microbiome of the Fetus and Newborn; Hereditary Contribution to Neonatal Hyperbilirubinemia; Mechanistic Aspects of Phototherapy for Neonatal Hyperbilirubinemia; Cerebellar Development; Pathophysiology of Neonatal Sepsis; Pathophysiology of Persistent Pulmonary Hypertension of the Newborn; Pathophysiology of Meconium Aspiration Syndrome; Pathophysiology of Ventilator Dependent Infants; Pathophysiology of Hypoxic-Ischemic Brain Injury; Pathophysiology of Neonatal White Matter Injury; Pathophysiology of Meningitis; Pathophysiology of Preeclampsia; and Pathophysiology of Chorioamnionitis. New Pathophysiology of Neonatal Diseases section highlights every process associated with a disease or injury, all in one place. In-depth information, combined with end-of-chapter summaries, enables deep or quick use of the text.

First multi-year cumulation covers six years: 1965-70.

A complete practice-oriented introduction to physical pharmacy Written to clearly and simply explain how drugs work, this textbook explores the fundamental physicochemical attributes and processes important for understanding how a drug is transformed into a usable product that is administered to a patient to reach its pharmacological target, and then exists the body. Applied Physical Pharmacy, Third Edition begins with a review of the key biopharmaceutics concepts of drug liberation, absorption, distribution, metabolism, and excretion. These concepts, and others, set the framework for the subsequent chapters that describe physicochemical properties and process related to the fate of the drug. Other physical pharmacy topics important to drug formulation are discussed in the chapters that follow, which describe dispersal systems, interfacial phenomena, and rheology. The textbook concludes with an overview of the principles of kinetics that are important for understanding the rates at which many of the processes discussed in previous chapters occur. Chapters in this Third Edition retain the acclaimed learning aids of previous editions, including Learning Objectives, Practice Problems, Key Points, and Clinical Questions. In order to be of greater value to the pharmacy student, more clinical questions have been added, and many tables have been updated with more current products and excipients.