* Discusses human, mammalian, insect and plant viruses in invertebrate cell culture systems* Addresses the commercial application of these systems in biotechnology and insect pest control* Brings together for the first time in over two decades the large body of information and significant achievements in the field

To lose is human, to win is fortune, but to try is our destiny. EARL C. SUITOR, JR. The idea of a Symposium on "Arthropod Cell Cultures" started in July of 1969 shortly after the untimely death of our colleague, EARL C. SUITOR, JR. , at the age of 38. At first we thought an afternoon or evening session would be sufficient, but we were soon convinced that the scope of the Symposium should be greatly enlarged. Interest in this topic was increasing at an astonishing rate. Since EARL SUITOR had made a distinct imprint in this new field, many scientists who knew him well or just casually wished to honor him in this manner. EARL SUITOR was born and raised in New England and received a B. S. degree in bacteriology from the University of Massachusetts in 1952. As a spirited young man, he enlisted in the U. S. Navy to see the world. Instead, he was assigned for most of his four-year "hitch" to the Naval Medical Research Institute. I met him there in 1954, an enthusiastic and imaginative young fellow with many interests, an avid reader of the classics, an occasional writer of poetry, who blended his interest in scientific literature with that of Science Fiction. In 1956, EARL left the Navy to attend George Washington University, where he earned an M. S. degree in 1958 and a Ph. D. degree in 1963.

Invertebrate cell culture is increasingly being used in various areas of biological research. Research in cellular biology and pathology that previously depended primarily on in vitro investigations of vertebrate animal cell systems is now being conducted using invertebrate cells. Specialists and pioneers from the United States, Japan, Switzerland, Slovakia, and China have presented original contributions to create a well-balanced cross-section of current developments. Topics discussed include the preparation of cell culture media; cultivation of mosquito, lepidopteran, grasshopper, and tick cells; the application of such cells to mammalian and plant virus research; and diverse applications in medicine, biology, and agriculture. A special chapter devoted to the work of Japanese cell culture pioneers is also featured. All chapters are supported by tables, photographs, and up-to-date bibliographies.

Growth, Nutrition, and Metabolism of Cells in Culture, Volume 2, summarizes the state of knowledge of the growth, nutrition, and metabolism of various types of cell cultures. The chapters are both detailed and comprehensive enough for the specialist and broad enough to provide a general background for the nonspecialist. The present volume deals with specialized mammalian, plant, and invertebrate cell systems and techniques. The book begins by tracing the history of the development of tissue culture. This is followed by separate chapters on the use of perfusion systems in cell and tissue culture; and the cultivation of muscle tissue, nerve tissue, and hematopoietic cells. Subsequent chapters discuss the use of cell culture to study mechanisms of hormone action; the cultivation of mammalian embryos; cultivation of cells from poikilothermie vertebrates; and the cultivation of arthropod cells and plant cells. This book will be valuable resource for investigators who routinely use cell culture techniques, as well as students and individuals in associated areas of cell and molecular biology.

The Togaviruses: Biology, Structure, Replication deals with the biology, structure, and replication of rotaviruses. This book covers topics such as the biochemistry of rotaviruses and the biological and medical challenges they pose. It also gives an account of their mechanisms of replication that might lead to perceptions of the capacity to solve biological and epidemiological problems through the concepts and technology of molecular biology. This text is comprised of 21 chapters that explore clinical details, routine procedures for diagnostic virus isolation and identification and for serological tests; immunological host responses; the role of interferons; antiviral chemotherapy; and vaccine development. The discussion begins with a historical overview of arboviruses, followed by a description of all the viruses that belong to Togaviridae. These include alpha- and flaviviruses, rubiviruses, pestiviruses, and other ""non-arbo"" togaviruses. The next chapters focus on the arthropod-vertebrate-arthropod transmission cycle and its experimental equivalents, along with the viruses' structure, composition, and replication. This book concludes with a summary of physicochemical, morphological, and clinical data on non-arbo togaviruses. This reference material will be of interest to physicians, veterinarians, ecologists, entomologists, epidemiologists, cell biologists, immunologists, virologists, physical chemists, biochemists, molecular biologists, and geneticists.

those who deal with infectious diseases on a daily This two volume work stems from the belief of the Editors that infectious diseases are not only very basis. much with us today but, more importantly, that they There are several excellent textbooks dealing will continue to playa significant global role in mor with medical microbiology, and there are equally bidity and mortality in all people. A continuing need well-recognized books devoted to infectious dis for an informed and knowledgeable community of eases. The Editors of this work, on the other hand, were persuaded that there was a need for a publica laboratory scientists is fundamental. Data describing tion that would bring together the most pertinent and the global impact of infectious diseases are difficult to come by. Fortunately, a recent thoughtful and relevant information on the principles and practice of provocative publication by Bennett et al. (1987) pro the laboratory diagnosis of infectious diseases and vides us with data derived from several consultants include clinical relationships. While this two volume that clearly delineate the impact of infectious dis text is directed toward the role of the laboratory in eases on the United States today.

Fenner's Veterinary, Virology, Fourth Edition, is the long awaited new edition of Veterinary Virology, 3e, which was published in 1999. Fully revised and updated by the new author team, part I presents the fundamental principles of virology related to animal infection and disease, and part II addresses the clinical features, pathogenesis, diagnosis, epidemiology and prevention of individual diseases. New to this Edition - New author team - one main author to ensure that the book reads like an authored book but with the benefit of using experts to contribute to specific topics - Text has been refocused - part I has been condensed and where appropriate incorporated into part II to make it more user friendly - The number of figures have been increased and are now in full color - Fully revised and updated to include the latest information in the field of veterinary virology - Beautifully illustrated color figures throughout - Organized and current information provided by an expert team of authors