Assessing Nanoparticle Risks to Human Health provides a systematic overview of nanoparticle risks and considers the limitations of this paradigm in a context where extreme uncertainties prevail. As well as exploring conventional risk assessment methodology, the contributing authors investigate several alternate approaches. The adequacy of current frameworks for risk management and regulatory oversights, including corporate approaches in the US and EU, are explored, and suggestions are made as to how these frameworks can be modified to make them more efficient and effective.Presenting a coherent framework for analysis of the available information, this book presents the latest scientific understanding of the toxicity and health effects of nanoparticles, the technical issues relating to exposure assessment and management, and the ways in which the current risk paradigm can be used/modified to deal with the challenges of nanoparticle risks.All chapters of this new edition have been thoroughly updated to reflect the many changes in the field since the first edition. Additions and updates in the second edition of the book include: - New exposure assessment strategies for nanomaterials including life cycle exposure assessment approaches and detailed information on nanoparticle exposure control and protection in the workplace. - A state-of-the-art scientific update on the hazard and risk assessment of nanomaterials: discussion of key additional publications on the toxicology and biokinetics of nanomaterials; available data and methods to characterize the health hazard and risk of exposure to nanomaterials in the workplace; additional examples of the use of such data and methods to develop occupational safety and health guidance; and discussion of progress to date, ongoing efforts, and remaining challenges in nanomaterials hazard and risk characterization. - New studies on the use of expert judgment in nanotechnology. - Quantitative data from Lawrence Berkeley National Laboratory's 4-phase study. - A description and evaluation of new CB tools and new ISO technical specifications. - A comprehensive update of the legal frameworks in the US and the EU. With the second edition of Assessing Nanoparticle Risks to Human Health Prof. Ramachandran provides researchers and practitioners producing or using nanoparticles, or those involved in nanomaterials risk assessments, technology, health science, policy, safety, environment and regulatory aspects an invaluable reference to adopt the right technologies and strategies and to comply to legal frameworks and regulations. For policy makers and advisory firms it provides the knowledge needed to advise on compliance with or development of new regulations on nanomaterials. - Makes essential reading for risk assessment professionals, companies working with nanoparticles, nanotechnology research groups and regulators - Explores the use of risk assessment methodologies in an occupational health setting, and their limitations - Provides a framework for evidence-based decision making in a context with many uncertainties

Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity is an indispensable introduction to engineered nanomaterials (ENM) and their potential adverse effects on human health and the environment. Although research in the area of pharmacology and toxicology of ENM is rapidly advancing, a possible correlation between their physicochemical properties and biomedical properties or toxicity is not yet fully understood. This understanding is essential to develop strategies for the safe applications and handling of ENM. The book comprehensively defines the current understanding of ENM toxicity, first describing these materials and their physicochemical properties, and then discussing the toxicological theory and methodology before finally demonstrating the potential impact of ENM on the environment and human health. It represents an essential reference for students and investigators in toxicology, pharmacology, chemistry, material sciences, medicine, and those in related disciplines who require an introduction to ENM and their potential toxicological effects. - Provides state-of-the-art physicochemical descriptions and methodologies for the characterization of engineered nanomaterials (ENM) - Describes the potential toxicological effects of ENM and the nanotoxicological mechanisms of action - Presents how to apply theory to practice in a public health and risk assessment setting

As the application of nanotechnology in the myriad disciplines of science and engineering--from agriculture, pharmaceuticals, material science, and biotechnology to sensors, electronics, and mechanical and electrical engineering--brings benefits it also can produce serious threats to human health and the environment that must be evaluated. The unique properties of nanomaterials make them different from their bulk counterparts. In addition to such unique properties, the nanometric size of nanomaterials can invite some detrimental effects on the health and well-being of living organisms and the environment. Thus, it is important to distinguish nanomaterials with such ill effects from nanomaterials with no or minimum toxicity. Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management covers issues such as the basic principles of nanotoxicity, methods used for nanotoxicity evaluation, risk assessment and its management for nanomaterial toxicity with a focus on current trends, limitations, challenges, and future directions of nanotoxicity evaluation. Various experts from different countries discuss these issues in detail in this book. This will be helpful to researchers, educators, and students who are interested in research opportunities for avoiding the environmental and health hazards of nanomaterials. This book will also be useful for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, drugs, and other regulatory sciences.

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field

Since the first edition in 1948, Patty’s Industrial Hygiene and Toxicology has become a flagship publication for Wiley. During its nearly seven decades in print, it has become a standard reference for the fields of occupational health and toxicology. The volumes on industrial hygiene are cornerstone reference works for not only industrial hygienists but also chemists, engineers, toxicologists, lawyers, and occupational safety personnel. Volume 1 covers Introduction of Industrial Hygiene and Recognition of Chemical Agents. In addition to revised and updated chapters, a number of new chapters reflect current technology and concerns. The chapters include Ethics in Industrial Hygiene, Prevention through Design, Risk Communication, Managing Workplace Demographics, and Mastering Digital Media for Workers, Employers and Community Practice.

Magnetic nanoparticles (MNPs) uniquely combine superparamagnetic performance with dimensions that are smaller than or similar size to molecular analytes. Recently, functionalized MNPs are predicted to be a driver for technology and business in this century and hold the promise of high performance materials that will significantly influence all aspects of society. Functionalized MNPs are creating new possibilities for development and innovation in different analytical procedures. Despite their participation in modern development, they are in their infancy and largely unexplored for their practical applications in analysis. This book will provide quality research and practical guidance to analytical scientists, researchers, engineers, quality control experts and laboratory specialists. It covers applications of functionalized MNPs in all stages of analytical procedures. Their incorporation has opened new possibilities for sensing, extraction and detection enabling an increase in sensitivity, magnifying precision and improvement in the detection limit of modern analysis. Toxicity, safety, risk, and legal aspects of functionalized MNPs and the future of analytical chemistry with respect to their use is covered. The book provides an integrated approach for advanced analytical methods and techniques for postgraduates and researchers looking for a reference outlining new and advanced techniques surrounding the applications of functionalized nanomaterials in analytical chemistry.

This timely publication bridges and presents the latest trends and updates in three hot topics of current and future society: nanomaterials, energy and environment. It provides the state-of-the-art as well as current challenges and advances in the sustainable preparation of metal nanoparticles and their applications. The book fills a critical gap in a multidisciplinary area of high economic, social and environmental importance. Currently, there are no books published that deal with these ever increasing important topics, as most books in this area focus on a particular topic (eg. nanomaterials or catalysis or energy or environment). This is the first multidisciplinary edited book covering the very basics to the more advanced, trendy developments, containing a unique blend of nano, green, renewable and bio.

Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems An indispensable compendium detailing the toxicology of nanoparticles with a focus on mechanisms, emerging issues, and new approaches Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems provides authoritative information on the toxicology of ultrafine and nanoparticulate matter that contaminate terrestrial or aquatic environments and present unique challenges in applied public health and toxicological research. Detailed chapters by a panel of world-renowned experts examine the complementary and dynamic interdependence of aquatic, terrestrial, and human systems and the toxicological impacts on exposure to engineered and manufactured nanoparticles and nanomaterials. Organized into four sections, the book opens with a thorough overview of the field, including known challenges and the necessity for current research activity. The second section describes terrestrial and aquatic systems and the ecotoxicological impact of nanomaterials, followed by critical analysis of the many human health effects of nanomaterials. The book concludes with an in-depth discussion of current gaps in knowledge, future directions, new approach methodologies, alternatives to animal models, and the emerging environmental threat from nanoplastics. Presenting case exemplars of the ecotoxicological impact of nanoparticles in aquatic and terrestrial systems, this important resource: Presents in-depth coverage of ecosafety, environmental behavior, fate and transport, interactive effects with other contaminants, and current challenges in soil nano-ecotoxicology Addresses rising concerns regarding air pollution and neurological disorders, and the roles played by the gastrointestinal system, the mucosal microbiome, and the immunotoxicology and vasculotoxicity of metal-based nanoparticles Provides detailed coverage of nanomaterial health effects from both animal and in vitro models, including the gut microbiome, innate immunity, neurological and cardiovascular impacts, mechanisms of action, and hazard characterization Analyzes key topics in ecological nanotoxicology such as environmental micro- and nano-plastic pollution and applied risk assessment Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems is essential reading for toxicologists, applied biologists, ecotoxicologists, research scientists, medical professionals, regulators, and advanced students in fields such as public health, environmental ecotoxicology and medicine, immunotoxicology, neurotoxicology, cardiovascular and systems biology, hazard identification, and risk assessment.

Nanotechnology in the Beverage industry: Fundamentals and Applications looks at how nanotechnology is being used to enhance water quality, as well as how the properties of nanomaterials can be used to create different properties in both alcoholic and no-alcoholic drinks and enhance the biosafety of both drinks and their packaging. This is an important reference for materials scientists, engineers, food scientists and microbiologists who want to learn more about how nanotechnology is being used to enhance beverage products. As active packaging technology, nanotechnology can increase shelf-life and maintain the quality of beverages. In the field of water treatment, nanomaterials offer new routes to address challenges. - Describes the major properties that make nanomaterials good agents for increasing the purification of water and other beverages - Outlines major nanoencapsulation techniques for use in a variety of beverage types - Discusses the major challenges of using nanomaterials in both beverages and beverage packaging

Handbook of Functionalized Nanomaterials: Environmental Health and Safety discusses the reactive properties of FNMs used in a range of applications, and their toxic impact on the environment. Nanomaterials have unique properties that can make them highly reactive. This reactivity can cause unwanted interactions with living cells, an increase in oxidative stress or damage to genetic material - resulting in damage to the environment and local wildlife. This negative impact is often further increased after surface functionalization of nanomaterials with other materials which offer unique properties of their own. To ensure environmental safety and ecological balance, rigorous toxicity testing of functionalized nanomaterials (FNMs) is necessary. This book discusses the toxicological uncertainties of FNMs and the limitations of FNMs in a range of applications. Later chapters propose methods to reliably assess the harm that functionalized nanomaterials can cause to the environment and wildlife, as well covering recent developments in the field of environmental health safety. The book concludes with a discussion on the future prospects of safe functionalized nanomaterials. - Offers a novel, integrated approach, bridging the gap between FNMs and environmental health and safety - Analyses the reactive properties of FNMs and their toxicological potential - Provides an in-depth look at the impact of functionalized nanomaterials on the environment