Biological NMR, Part B, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs & micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery, Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration, Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, and much more. - Authoritative contributors - Protocols for state-of-the-art advances - Timeliness

First multi-year cumulation covers six years: 1965-70.

This book describes nuclear magnetic resonance (NMR) methods which are used to study translational dynamics of molecules in different complex systems including systems made of synthetic and natural polymers, tissues and the porous heterogeneous systems of different types, such as cement and wood. The results of proton spin-lattice and spin-spin relaxation, cross-relaxation, pulse field gradient (PFG) NMR in studying diffusion properties and dynamics of molecules in polymer systems of different complexity are reported. In addition to these methods, reports on the use of the double-quantum-filtered (DQF) NMR technique in a study of slow molecular dynamics and properties of systems with anisotropic properties, such as water in hardening cement pastes, are presented. The book also covers applications of one and two dimensional NMR techniques. This book is a useful reference for readers learning different NMR techniques and their applications in civil engineering and biochemistry.

This third edition of the Encyclopedia of Spectroscopy and Spectrometry, Three Volume Set provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry. Incorporates more than 150 color figures, 5,000 references, and 300 articles for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Presents a one-stop resource for quick access to answers and an in-depth examination of topics in the spectroscopy and spectrometry arenas

Virtually every area of research associated with sharks and their relatives has been strongly impacted by the revolutionary growth in technology. The questions we can now ask are very different than those reported even two decades ago. Modern immunological and genetic techniques, satellite telemetry and archival tagging, modern phylogenetic analysis, GIS, and bomb dating, are just a few of the techniques and procedures that have become a part of our investigative lexicon. A modern synthesis of the biology of Chondrichthyans, Biology of Sharks and Their Relatives, Second Edition discusses significant advances in the development and application of new molecular techniques to the understanding of the phylogenetic relationships among and between these groups. The book considers the effect of global changes on the status of sharks and their relatives, and how advances in technology and analytical techniques have changed not only how we approach problem solving and scientific investigations, but how we formulate questions. The book also introduces applications of new and novel laboratory devices, techniques, and field instruments. This second edition of the award winning and groundbreaking original exploration of the fundamental elements of the taxonomy, systematics, physiology, and ecology of sharks, skates, rays, and chimera, presents cohesive and integrated coverage of key topics and discusses technological advances used in modern shark research. Offering a well-rounded picture for students and researchers, and far above competitors in scope and research, this new volume holds a wealth of data on the current status of Chondrichthyan research and provides the basis and springboard for original research. Cover photo by Justin Gilligan

A riveting explanation of epigenetics, offering startling insights into our inheritable traits. In the 1700s, Jean-Baptiste Lamarck first described epigenetics to explain the inheritance of acquired characteristics; however, his theory was supplanted in the 1800s by Darwin's theory of evolution by natural selection through heritable genetic mutations. But natural selection could not adequately explain how rapidly species re-diversified and repopulated after mass extinctions. Now advances in the study of DNA and RNA have resurrected epigenetics, which can create radical physical and physiological changes in subsequent generations by the simple addition of a single small molecule, thus passing along a propensity for molecules to attach in the same places in the next generation. Epigenetics is a complex process, but paleontologist and astrobiologist Peter Ward breaks it down for general readers, using the epigenetic paradigm to reexamine how the history of our species-from deep time to the outbreak of the Black Plague and into the present-has left its mark on our physiology, behavior, and intelligence. Most alarming are chapters about epigenetic changes we are undergoing now triggered by toxins, environmental pollutants, famine, poor nutrition, and overexposure to violence. Lamarck's Revenge is an eye-opening and provocative exploration of how traits are inherited, and how outside influences drive what we pass along to our progeny.