This handbook systematically presents biomarkers for traumatic injuries. The book covers topics such as traumatic brain injury, liver injury, burn severity, muscle heart damage, and acute inflammation in polytrauma and their detection by biomarkers. Biomarkers and methods used in critical care and critically ill patients are discussed, as well as biomarkers in trauma and special conditions. Specific biomarker components are explained and models for modeling trauma in research are presented. This systematic handbook is an excellent resource for researchers and specialists in trauma research and treatment, as well as clinicians and physicians who want a thorough overview of various injuries, trauma, and their detection methods.

Comprehensive, concise, and readable, Textbook of Critical Care, 7th Edition, brings you fully up to date with the effective management of critically ill patients, providing the evidence-based guidance you need to overcome a full range of practice challenges. Drs. Jean-Louis Vincent, Edward Abraham, Frederick A. Moore, Patrick Kochanek, and Mitchell P. Fink are joined by other international experts who offer a multidisciplinary approach to critical care, sharing expertise in anesthesia, surgery, pulmonary medicine, and pediatrics. This highly acclaimed text offers ICU clinicians a new understanding of the pathophysiology of critical illness and new therapeutic approaches to critical care. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Features a wealth of tables, boxes, algorithms, diagnostic images, and key points that clarify important concepts and streamline complex information for quick reference. - Includes many new chapters on echocardiography, antibiotic stewardship, antiviral agents, coagulation and anti-coagulation, , telemedicine, extracorporeal membrane oxygenation (ECMO), and more. - Offers new coverage of biomarkers, bedside ultrasound, and the management of increasingly complex critically ill patients. - Provides new approaches to sepsis, acute kidney injury, and management of acute respiratory distress syndrome (ARDS), and other forms of respiratory failure.

Guest edited by Dr. Michell Levy, articles for this edition of Critical Care Clinics include: Specificity and sensitivity; How to use biomarkers;Physiologic Parameters as biomarkers: What can we learn from physiologic variables and variation?;Multi-marker Panels;Coagulation biomarkers;Biomarkers in neurosurgery;Biomarkers in Trauma; and Cardiac Biomarkers

Bridging the gap between medical and surgical specialties in critical care, Textbook of Critical Care, 8th Edition, offers a practical, multidisciplinary approach to the effective management of adult and pediatric patients in the ICU. An outstanding editorial team, led by world-renowned intensivist Dr. Jean-Louis Vincent, assisted by Dr. Frederick A. Moore and new editors Drs. Rinaldo Bellomo and John J. Marini, provides the evidence-based guidance you need to overcome a full range of practice challenges. A full-color art program, relevant basic science and key summary points in every chapter, and expert contributing authors from all over the world make this an indispensable resource for every member of the critical care team. - Provides a concise, readable understanding of the pathophysiology of critical illness and new therapeutic approaches to critical care. - Addresses both medical and surgical aspects in critical care for adult and pediatric patients in one comprehensive, easy-to-use reference. - Shares the knowledge and expertise of the most recognized and trusted leaders in the field, with more international contributing authors than in previous editions. - Covers new information on procedural and diagnostic ultrasound, prone positioning, ECMO, and VADs. - Discusses key topics such as organ support, telemedicine, echocardiography, antibiotic stewardship, antiviral agents, coagulation and anti-coagulation, and more. - Features a wealth of tables, boxes, algorithms, diagnostic images, and key points that clarify important concepts and streamline complex information for quick reference. - Includes companion videos and exclusive chapters online that cover commonly performed procedures. - Takes a multidisciplinary approach to critical care, with contributions from experts in anesthesia, surgery, pulmonary medicine, and pediatrics. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

This book is a comprehensive guide to the monitoring of different organ systems in anaesthetics and intensive care. Divided into nine sections, the text begins with an introduction to the evolution of monitoring equipment, computerised reporting, and minimum standards. The following sections cover monitoring techniques for different systems of the body – cardiovascular, respiratory, central and peripheral nervous, musculoskeletal, metabolic, and coagulation. The final chapters discuss the monitoring of pain and related topics such as ventilator waveforms, foetal monitoring, and future technologies. The book also features discussion on research-based monitoring ideas for the future, including quantifying pain, sedation, and maternal-foetal safety management. Key points Comprehensive guide to the monitoring of organ systems in anaesthetics and intensive care In depth coverage of many different systems of the body Includes discussion on pain monitoring and future technologies Highly illustrated with clinical photographs and diagrams

The Practice of Emergency and Critical Care Neurology is the classic and comprehensive reference for physicians caring for patients with critical neurologic disorders, at risk of deterioation and in need of immediate attention. This third edition is richly illustrated and contains new chapters on the basics of neuroimaging, pharmacology issues in the intensive care setting, intoxications, critical care ultrasound, and more.

This text is designed to provide a comprehensive and state-of-the-art overview of the major issues specific to technological advances the field trauma, critical care and many aspects of surgical science and practice. Care of these patients and clinical conditions can be quite complex, and materials have been collected from the most current, evidence-based resources. The sections of the text have been structured to review the overall scope of issues dealing with trauma, critical care and surgery, including cardiothoracic surgery, vascular surgery, urology, gynecology and obstetrics, fetal surgery and orthopedics. This volume represents the most comprehensive textbook covering a wide range of topics and technological advances including genomics and nanotechnologies that affect patients’ care and surgeons’ practice daily. The multidisciplinary authorship includes experts from all aspects of trauma, surgery and critical care. The volume highlights the dramatic changes in the field including hand held devices and smart phones used in daily medical and surgical practice, complex computers in the critical care units around the world, and robotics performing complex surgical procedures and tissue engineering. Technological Advances in Surgery, Trauma and Critical Care provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in trauma, critical care, and all the specialties of surgery. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.

Injury is recognized as a major public health issue worldwide. In most countries, injury is the leading cause of death and disability for children and young adults age 1 to 39 years. Each year in the United States, injury claims about 170,000 lives and results in over 30 million emergency room visits and 2.5 million hospitalizations. Injury is medically defined as organ/tissue damages inflicted upon oneself or by an external agent either accidentally or deliberately. Injury encompasses the undesirable consequences of a wide array of events, such as motor vehicle crashes, poisoning, burns, falls, and drowning, medical error, adverse effects of drugs, suicide and homicide. The past two decades have witnessed a remarkable growth in injury research, both in scope and in depth. To address the tremendous health burden of injury morbidity and mortality at the global level, the World Health Organization in 2000 created the Department of Injury and Violence Prevention, which has produced several influential reports on violence, traffic injury, and childhood injury. The biennial World Conference on Injury Control and Safety Promotion attracts a large international audience and has been successfully convened nine times in different countries. In the United States, the National Center for Injury Prevention and Control became an independent program of the federal Centers for Disease Prevention and Control in 1997. Since then, each state health department has created an office in charge of injury prevention activities and over a dozen universities have established injury control research centers. This volume will fill an important gap in the scientific literature by providing a comprehensive and up-to-date reference resource to researchers, practitioners, and students working on different aspects of the injury problem and in different practice settings and academic fields.

This issue of Critical Care Clinics will focus on Severe Acute Respiratory DIstress Syndrome and dealing with it in the ICU. Topics will include: Challenges and Successes in ARDS Research;Mechanical ventilation with Lung Protective Strategies: What works?; Gene therapy for ALI/ARDS;High Frequency Oscillatory Ventilation in ALI/ARDS;Prone positioning therapy in ARDS;Recovery and Long-term outcome in ARDS; and Experimental models and emergeing hypotheses for ALI and ARDS