Bone tissue engineering aims to develop artificial bone substitutes that partially or totally restore the natural regeneration capability of bone tissue lost under circumstances of injury, significant defects, or diseases such as osteoporosis. In this context, biomaterials are the keystone of the methodology. Biomaterials for bone tissue engineering have evolved from biocompatible materials that mimic the physical and chemical environment of bone tissue to a new generation of materials that actively interacts with the physiological environment, accelerating bone tissue growth. Mathematical modelling and simulation are important tools in the overall methodology. This book presents an overview of the current investigations and recent contributions in the field of bone tissue engineering. It includes several successful examples of multidisciplinary collaboration in this transversal area of research. The book is intended for students, researchers, and professionals of a number of disciplines, such as engineering, mathematics, physics, chemistry, biomedicine, biology, and veterinary. The book is composed of an editorial section and 16 original research papers authored by leading researchers of this discipline from different laboratories across the world

Bone tissue engineering aims to develop artificial bone substitutes that partially or totally restore the natural regeneration capability of bone tissue lost under circumstances of injury, significant defects, or diseases such as osteoporosis. In this context, biomaterials are the keystone of the methodology. Biomaterials for bone tissue engineering have evolved from biocompatible materials that mimic the physical and chemical environment of bone tissue to a new generation of materials that actively interacts with the physiological environment, accelerating bone tissue growth. Mathematical modelling and simulation are important tools in the overall methodology. This book presents an overview of the current investigations and recent contributions in the field of bone tissue engineering. It includes several successful examples of multidisciplinary collaboration in this transversal area of research. The book is intended for students, researchers, and professionals of a number of disciplines, such as engineering, mathematics, physics, chemistry, biomedicine, biology, and veterinary. The book is composed of an editorial section and 16 original research papers authored by leading researchers of this discipline from different laboratories across the world.

This book comprehensively explores the basic concepts and applications of biomaterials in tissue engineering and regenerative medicine. The book is divided into four sections; the first section deals with the basic concepts and different types of biomaterials used in tissue engineering. The second section discusses the functional requirements and types of materials that are used in developing state-of-the-art of scaffolds for tissue engineering applications. The third section presents the applications of biomaterials for hard and soft tissue engineering, as well as for specialized tissue engineering. The last section addresses the future prospects of nanobiomaterials, intelligent biomaterials, and 3D bioprinting biomaterials in tissue engineering and regenerative medicine. It also discusses various in vitro disease models for tissue bioengineering and regenerative medicine. As such, it offers a valuable resource for students, researchers, scientists, entrepreneurs, and medical/healthcare professionals.

Special topic volume with invited peer reviewed papers only.

Nanoengineered Biomaterials for Regenerative Medicine showcases the advances that have taken place in recent years as an increasing number of nanoengineered biomaterials have been targeted to various organ tissues. The book systematically explores how nanoengineered biomaterials are used in different aspects of regenerative medicine, including bone regeneration, brain tissue reconstruction and kidney repair. It is a valuable reference resource for scientists working in biomaterials science who want to learn more about how nanoengineered materials are practically applied in regenerative medicine. Nanoengineered biomaterials have gained particular focus due to their many advantages over conventional techniques for tissue repair. As a wide range of biomaterials and nanotechnology techniques have been examined for the regeneration of tissues, this book highlights the discussions and advancements made. - Provides a digestible reference source for surgeons and physicians who want to learn more on nanoengineered biomaterials and their use in effective medical treatments - Offers systematic coverage on how nanoengineered biomaterials are used for different types of medicine - Assesses the benefits and drawbacks of the use of bioengineered nanomaterials in different areas of regenerative medicine

Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Nanotechnology and high-end characterization techniques have highlighted the importance of the material choice for the success of tissue engineering. A paradigm shift has been seen from conventional passive materials as scaffolds to smart multi-functional materials that can mimic the complex intracellular milieu more effectively. This book presents a detailed overview of the rationale involved in the choice of materials for regeneration of different tissues and the future directions in this fascinating area of materials science with specific chapters on regulatory challenges & ethics; tissue engineered medical products.

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters

Novel Biomaterials for Bone Regeneration provides a comprehensive review of currently available biomaterials and how they can be applied in bone regeneration. In recent decades, there has been a shift from the idea of using biomaterials as passive substitutes for damaged bones towards the concept of biomaterials as aids for the regeneration of a host's own bone tissue. This has generated an important field of research and a range of technological developments. Part one of this book discusses a wide range of materials, including calcium phosphate cements, hydrogels, biopolymers, synthetic polymers, and shape memory polymers. Part two then turns to the processing and surface modification of biomaterials, as well as how biomaterials can be evaluated both for their mechanical properties and for immunocompatibility with the host. Finally, part three covers a variety of cellular approaches, and production and delivery of biomaterials for bone regeneration. Chapters also consider the potential of electromagnetic and ultrasonic stimulation of biomaterials to aid in the regenerative process. Novel Biomaterials for Bone Regeneration represents an important resource for academics, clinicians, and industry professionals working in the area of biomedical materials, providing them with both an overview of the current state-of-the-art, and an indication of potential future developments. - Provides comprehensive coverage of novel materials, techniques, and applications of biomaterials for bone regeneration - Provides vital information on the various types of materials used in bone regeneration - Discusses processing, modification, and evaluation techniques of biomaterials, and looks at cellular approaches and stimulation of biomaterials for bone regeneration