This book is a unique overview of insights on the genetic basis of anti-diabetic activity, chemistry, physiology, biotechnology, mode-of-action, as well as cellular mechanisms of anti-diabetic secondary metabolites from medicinal plants. The World Health Organization estimated that 80% of the populations of developing countries rely on traditional medicines, mostly plant drugs, for their primary health care needs. There is an increasing demand for medicinal plants having anti-diabetic potential in both developing and developed countries. The expanding trade in medicinal plants has serious implications on the survival of several plant species, with many under threat to become extinct. This book describes various approaches to conserve these genetic resources. It discusses the whole spectrum of biotechnological tools from micro-propagation for large-scale multiplication, cell-culture techniques to the biosynthesis and enhancement of pharmaceutical compounds in the plants. It also discusses the genetic transformation as well as short- to long-term conservation of plant genetic resources via synthetic seed production and cryopreservation, respectively. The book is enriched with expert contributions from across the globe. This reference book is useful for researchers in the pharmaceutical and biotechnological industries, medicinal chemists, biochemists, botanists, molecular biologists, academicians, students as well as diabetic patients, traditional medicine practitioners, scientists in medicinal and aromatic plants, Ayurveda, Siddha, Unani and other traditional medical practitioners.

Diabetes is a chronic condition associated with metabolic disorder. Persons suffering from diabetes have shown accelerated levels of blood sugar which often harms the heart, blood vessels, eyes, kidneys, and nerves. Over the past few decades, the prevalence of diabetes has been progressively increasing. Synthetic drugs are used to treat diabetic patients to help control the disorder, but it is shown that numerous medicinal plants and herbal drugs are widely used in several traditional systems of medicine to prevent and treat diabetes. They are reported to produce beneficial effects in combating diabetes and alleviating diabetes-related complications. These plants contain phtyonutrients and phytoconstituents demonstrating protective or disease preventive properties. In many developing countries, herbal drugs are recommended by traditional practitioners for diabetes treatment because the use of synthetic drugs is not affordable. Key Features: Provides botanical descriptions, distribution, and pharmacological investigations of notable medicinal and herbal plants used to prevent or treat diabetes Discusses phytochemical and polyherbal formulations for the management of diabetes and other related complications Contains reports on antidiabetic plants and their potential uses in drug discovery based on their bioactive molecules This volume in the Exploring Medicinal Plants series provides an overview of natural healing treatments in selected antidiabetic plants. The book presents valuable information to scientists, researchers, and students working with medicinal plants or for those specializing in areas of ethnobotany, natural products, pharmacognosy, and other areas of allied healthcare. It is also useful to pharmaceutical companies, industrialists, and health policy makers.

This contributed volume provides a comprehensive, in-depth and subject-based reviews on the current status of active ingredients, sustainable use, biodiversity and conservation of certain endangered medicinal plants. The book also explores conventional and non-conventional biotechnological interventions for their biodiversity conservation. Medicinal plants have been used in worldwide as a major source of raw material for the traditional herbal healthcare practices as well as for drug discovery and development in pharmaceutical industry. The cumulative consequences of various human activities and environmental factors cause decline in the biodiversity of medicinal plants at an unprecedented rate worldwide. Thus, the overall understanding of ecology, species and genetic diversity along with assessment of the status of different threats and their impact on medicinal plants is crucial to sustain existing biodiversity, its utilization and conservation. All the latest advancements in the biotechnological approaches for the conservation research of endangered medicinal plants and the future perspectives have been described. This book provides comprehensive reviews spreading over about 25 chapters divided in three sections. The chapters of this book are written by recognized scientists in their respective fields which are useful to students, academicians, researchers, botanists, biotechnologists, policy makers, conservationists and industries interested in biodiversity conservation and medicinal plant research for the production of secondary metabolites.

Plant-based medicines play an important role in all cultures, and have been indispensable in maintaining health and combating diseases. The identification of active principles and their molecular targets from traditional medicine provides an enormous opportunity for drug development. Using modern biotechnology, plants with specific chemical compositions can be mass propagated and genetically improved for the extraction of bulk active pharmaceuticals. Although there has been significant progress in the use of biotechnology, using tissue cultures and genetic transformation to investigate and alter pathways for the biosynthesis of target metabolites, there are many challenges involved in bringing plants from the laboratory to successful commercial cultivation. This book presents the latest advances in the development of medicinal drugs, including topics such as plant tissue cultures, secondary metabolite production, metabolomics, metabolic engineering, bioinformatics and future biotechnological directions.

This book provides a comprehensive overview of medicinal plants and their interaction with abiotic stress in terms of morphological, physiological, biochemical, and molecular variations, and explains the adaptation and tolerance mechanisms involved. It presents various mechanisms that become operative in medicinal plants to combat stressful situations. The book discusses the secondary metabolites and/or bioactive compounds produced in medicinal plants under abiotic stress conditions, and the use of biostimulants and/or phytoprotectants to alleviate the adverse effects of abiotic stresses on medicinal plants. Additionally, it is likely to address opportunities and challenges in molecular and omics studies of medicinal plants under abiotic stress conditions. Overall, the chapters are developed by eminent subject experts with due care and clarity and cover an up-to-date literature review with relevant illustrations. The book would cater to the need of graduate and post-graduate students, researchers as well as scientists, and may attract the attention of pharmaceutical companies/industrialists and health policymakers.

This volume sheds new light on the immense potential of medicinal plants for human health from different technological aspects. It presents new research on bioactive compounds in medicinal plants that provide health benefits, including those that have proven especially effective in treating and managing diabetes mellitus and hypertension. It looks at the medicinal properties, antioxidant capacity, and antimicrobial activity of plants and provides scientific evidence on the use of medicinal plants in the treatment of certain diseases. Many of the plants described in the chapters are easily accessible and are believed to be effective with fewer side effects in comparison to modern drugs in the treatment of different diseases.

The book provides an overview of current trends in biotechnology and medicinal plant sciences. The work includes detailed chapters on various advance biotechnological tools involved in production of phytoactive compounds of medicinal significance. Some recent and novel research studies on therapeutic applications of different medicinal plants from various geographical regions of the world have also been included. These studies report the antimicrobial activity of various natural plant products against various pathogenic microbial strains. Informative chapters on recent emerging applications of plant products such as source for nutraceuticals and vaccines have been integrated to cover latest advances in the field. This book also explores the conservation aspect of medicinal plants. Thus, chapters having comprehensively complied in vitro conservation protocols for various commercially important rare, threatened and endangered medicinal plants were provided in the present book.

This edited book deals with medicinal plants (herbs and trees) used in critical diseases which contain a rich resource of bioactive compounds that can be used as immuno-boosters or recommended for therapeutic values. Each chapter provides the basic information such as taxonomic description, occurrence and importance of medicinal plants. The detail description of major bioactive compounds in medicinal plants, their chemical nature and clear flow chart of biosynthesis are important steps in this book. This book also includes conservation strategy both in-situ and ex-situ, which assist the research and academic purpose. This book is of interest to national and international researchers, teacher’s, pharma scientists, and policymakers. Also, the book serves as additional reading material for both undergraduate and graduate students of pharma and agriculture in the world.