Clinically accessible information for pathologists on histology, molecular pathology, differential diagnosis, and clinical overview is presented. Common and rare entities are covered with an abundance of images to highight key features.Topics for pathologists covering the fast moving field of breast pathology include: Less common variants and mimics of DCIS; Invasive lobular carcinoma and its variants; Important inflammatory and reactive lesions; Small glandular proliferations; Vascular lesions of the breast; Combined epithelial-myoepithelial lesion; Immunhistochemical pitfalls in the diagnosis of breast lesions; Pathology considerations in patients treated with neoadjuvant chemotherapy; Molecular classification of breast cancer: Jorge Reis-Filho; Prognostic factors for patients with breast cancer: Traditional and New

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

"Overall, this book is an excellent update on many important entities..." Reviewed by: Kay Lawson, on behalf of ACP News; Date: Summer 2014. The gastrointestinal tract may be affected by a diverse spectrum of inflammatory and neoplastic disorders, many of which pose problems for practicing surgical pathologists on a daily basis. Pathologists' understanding of these diseases continues to evolve rapidly. The topics in this issue of Surgical Pathology Clinics address a wide range of neoplasms and present ancillary techniques that play an increasingly important role in diagnostic pathology and include prognostic and predictive markers that have become a routine part of gastrointestinal pathology practice. These expert reviews provide surgical pathologists with critical practical updates on many of these challenging areas, with an emphasis on differential diagnosis and diagnostic pitfalls. Some topics include: Lymphomas of the gastrointestinal tract; Mesenchymal tumors of the gastrointestinal tract other than GIST; Barrett's esophagus: evolving concepts in diagnosis and neoplastic progression; Immunohistochemistry in neoplastic gastrointestinal pathology; HER2 testing in adenocarcinomas of the upper gastrointestinal tract; Pediatric inflammatory gastrointestinal pathology; IgG4-related disorders of the gastrointestinal tract. The reader will be interested in cross referencing the first volume on GI pathology presented in this series; its popularity with surgical pathologists has led to this second volume, which covers different topics in GI pathology. Jason Hornick of Brigham and Women's provides his expertise to lead this issue.

Obstetricical care and the growing number of pregnancies in older women or medically challenged women creates an expanding need for placental pathology that can provide information on neonatal care, risk assessment, and infant and mother outcomes. In the Surgical Pathology Clinics, Essential Gross Examination of the Placenta is presented with an abundance of images along with clear steps in the examination. Also presented are Placenta Accreta and Percreta; Ascending Infection – Acute Chorioamnionitis; Maternal Floor Infarction and Massive Perivillous Fibrin Deposition. Additionally, Umbilical Cord Pathology, Monozygotic Twinning, and Fetal Thrombotic Vasculopathy, Neonatal Stroke and other sequelae are discussed. Each of the topics presents abundant clinical photos and histology slides supporting diagnosis. Editor Rebecca Baergen, whose specialty areas are fetal pathology, placental pathology, gynecology and perinatal pathology, leads a group of authors who are experts in placental pathology, including her mentor and one of the pioneers in placental and perinatal pathology, Dr. Kurt Benirschke.

For the surgical pathologist, this coverage of Liver Pathology presents practical information with ample discussion of differential diagnosis and use of special studies, where relevant, to engage pathologists in what you can do daily in practice. Topics include: Steatohepatitis: Histopathologic diagnosis; Regression and subclassification of cirrhosis; Autoimmune hepatitis and overlap syndrome; Liver transplant pathology: challenging diagnostic situations; Hepatocellular adenoma; Immunohistochemistry for the diagnosis of hepatocellular carcinoma; Histologic subtypes of hepatocellular carcinoma: diagnostics and clinical significance; Pediatric cholestatic disorders. Sanjay Kakar and Dhanpat Jain bring their expertise in liver pathology and lead a group of authors whose focus is on liver and GI pathology. The surgical pathologist has at hand in this issue the essential and most current aspects of liver pathology required for daily practice.

This issue of Surgical Pathology Clinics, edited by Dr. Laura C. Collins, will focus on Breast Pathology. Topics include, but are not limited to: Core needle biopsy of the breast, Mucinous Lesions of the Breast: Pragmatic approach to fibroepithelial lesions; Lymph node inclusions; Differential diagnosis of benign spindle cell lesions of the breast; Ancillary Prognostic and Predictive Testing in Breast Cancer; Lesions of the Low Grade Breast Neoplasia Pathway; Genotype-Phenotype Correlation in Breast Neoplasia; Lobular Carcinoma in Situ; and Processing and Reporting of Breast Specimens in the Neoadjuvant Setting.

Breast cancer remains the leading cause of cancer in women, which makes accurate diagnoses on core needle biopsy (CNB) specimens of vital importance in staging and guiding therapy decisions for patients. The first edition of this multi-authored text written by leaders in the field from major academic medical centers provided a comprehensive guide on diagnostic breast pathology in the core biopsy setting. In addition to in-depth coverage of benign and malignant entities encountered in breast core biopsies, the book provided additional resources to improve diagnostic accuracy such as pattern-based approaches to evaluation, mimickers of breast lesions arising in extra-mammary sites, and pitfalls specific to small tissue samples. In recent years, there have been several notable developments in the field of breast pathology including revisions in AJCC breast cancer staging, updated guidelines in the testing and reporting of ER, PR, and HER2, as well as implementation of immunotherapy and companion biomarker testing. In addition, several key updates were included in the most recent edition of the WHO Classification of Breast Tumours (2020). In addition to updates specific to individual breast entities, the second edition will detail updates regarding biomarker testing in the primary and metastatic setting, and incorporate newly defined entities and updated definitions of rare tumors in alignment with the WHO Classification of Breast Tumours (2020). Furthermore, this edition will address the role of CNB in companion biomarker testing for eligibility for immunotherapy in the context of advanced triple-negative breast carcinoma. Written by leaders in the field and edited by expert breast pathologists, The Second Edition of Comprehensive Guide to Core Needle Biopsies of the Breast is the definitive reference on breast core needle biopsies for practicing pathologists, pathology trainees, oncologists and clinicians of patients with breast disease.

In this issue, guest editors bring their considerable expertise to this important topic. Contains 15 practice-oriented topics including new entities and challenges in pediatric hematopathology; IgG4-related lymphadenopathy and lymphoproliferative disorders; the changing landscape of follicular lymphoma: new variants and related entities; breast implant-associated lymphomas; controversies in splenic histiocytic, dendritic, and stromal cell lesions; and more. Provides in-depth clinical reviews on hematopathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

For over 60 years, residents and practicing pathologists have turned to Rosai and Ackerman's Surgical Pathology for definitive guidance on every aspect of the field, delivered in a readable, easy-to-digest, and engaging manner. In the 11th Edition, a dynamic new author team ensures that this classic text retains its signature anecdotal style, while revising the content to bring you fully up to date. Widely used for board exam preparation, as well as for everyday reference in practice, this leading resource equips you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. - Provides comprehensive coverage of the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, prognosis, and therapy for virtually every pathologic lesion. - Presents content now grouped in sections corresponding to organs and systems, making disease entities easier to locate. - Includes state-of-the-art coverage of the latest disease classifications, molecular biology and pathology, immunohistochemistry, genetics, prognostic/predictive markers, and more – all highlighted by more than 3,000 full-color illustrations of commonly seen pathologies. - Showcases the knowledge and expertise of an innovative new author team: prolific author John R. Goldblum, MD (GI pathology, soft tissue tumors); Laura Lamps, MD (hepatobiliary, endocrine tumors, infectious disease); Jesse McKenney, MD (GU/GYN, soft tissue tumors); and Jeff Myers, MD (pulmonary, pleural, mediastinum); accompanied by a select list of subspecialty contributors. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

In this issue of Surgical Pathology Clinics, guest editor Lauren L. Ritterhouse brings her considerable expertise to the topic of molecular pathology. - Provides in-depth, clinical reviews on molecular pathology, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.