The British Pharmacopoeia has provided official standards for the quality of substances, medicinal products and articles used in medicine since its first publication in 1864. It is used in over 100 countries and remains an essential global reference in pharmaceutical research and development and quality control. This book explores how these standards have been achieved through a comprehensive review of the history and development of the pharmacopoeias in the UK, from the early London, Edinburgh and Dublin national pharmacopoeias to the creation of the British Pharmacopoeia and its evolution over 150 years. Trade in medicinal substances and products has always been global, and the British Pharmacopoeia is placed in its global context as an instrument of the British Empire as it first sought to cover the needs of countries such as India and latterly as part of its role in international harmonisation of standards in Europe and elsewhere. The changing contents of the pharmacopoeias over this period reflect the changes in medical practice and the development of dosage forms from products dispensed by pharmacists to commercially manufactured products, from tinctures to the latest monoclonal antibody products. The book will be of equal value to historians of medicine and pharmacy as to practitioners of medicine, pharmacy and pharmaceutical analytical chemistry.

This adaptation of Bentley's Textbook of Pharmaceutics follows the same goals as those of the previous edition, albeit in a new look. The content of the old edition has been updated and expanded and several new chapters, viz. Complexations, Stability Testing as per ICH Guidelines, Parenteral Formulations, New Drug Delivery Systems and Pilot Plant Manufacturing, have been included, with an intention to make the book more informative for the modern pharmacists. The book has six sections: - Section I deals with the physicochemical principles. Two new chapters: Complexations and ICH Guidelines for Stability Testing, have been added to make it more informative. - Section II conveys the information regarding pharmaceutical unit operations and processes. - Section III describes the area of pharmaceutical practice. Extensive recent updates have been included in many chapters of this section. Two new chapters: Parenteral Formulations and New Drug Delivery Systems, have been added. - Section IV contains radioactivity principles and applications. - Section V deals with microbiology and animal products. - Section VI contains the formulation and packaging aspects of pharmaceuticals. Pilot Plant Manufacturing concepts are added as a new chapter, which may be beneficial to readers to understand the art of designing of a plant from the pilot plant model.

First multi-year cumulation covers six years: 1965-70.

The word "pharmacopoeia" has come to have many meanings, although it is commonly understood to be a book describing approved compositions and standards for drugs. In 1813 the Royal College of Physicians of London considered a proposal to develop an imperial British pharmacopoeia – at a time when separate official pharmacopoeias existed for England, Scotland, and Ireland. A unified British pharmacopoeia was published in 1864, and by 1914 it was considered suitable for the whole Empire. Pharmacopoeias, Drug Regulation, and Empires traces the 350-year development of officially sanctioned pharmacopoeias across the British Empire, first from local to national pharmacopoeias, and later to a standardized pharmacopoeia that would apply throughout Britain’s imperial world. The evolution of British pharmacopoeias and the professionalization of medicine saw developments including a transition from Galenic principles to germ theory, and a shift from plant-based to chemical medicines. While other colonial powers in Europe usually imposed metropolitan pharmacopoeias across their colonies, Britain consulted with practitioners throughout its Empire. As the scope of the pharmacopoeia widened, the process of agreeing upon drug standardization became more complex and fraught. A wide range of issues was exposed, from bioprospecting and the inclusion of indigenous medicines in pharmacopoeias, to adulteration and demands for the substitution of pharmacopoeial drugs with locally available ones. Pharmacopoeias, Drug Regulation, and Empires uses the evolution of an imperial pharmacopoeia in Britain as a vehicle for exploring the hegemonic power of European colonial powers in the medical field, and the meaning of pharmacopoeia more broadly.

Synthetic Dyes in Biology, Medicine and Chemistry is a guide in selecting dyes for special purposes in biology, medicine, chemistry, and other related fields. It aims to help professionals including histologists, cytologists, and other biology and medicine experts, such as chemists and general scientists. The dyes discussed in this book are categorized in 17 different classes according to the nature of their salt-forming sidechains, the colligators. This book also presents the uses of each dye. The spectral curve, which is the ionic and/or molecular weight of each dye, is also covered in this book. Likewise, this text provides the structural and empirical formulae of the spectral curve. Part I tackles various groups of dyes. These groups are the non-ionic, anionic, and cationic dyes. The anionic dyes are further grouped as wholly acid, weakly amphoteric, and moderately or strongly amphoteric. The subsequent part deals with the examples of dyes that do not fit the categories mentioned in Part I. These miscellaneous dyes are vat, reactive, disperse, and ingrain dyes. Part III presents the dyes in different tables according to wavelength of maximum absorption and ionic or molecular weight. This book also covers the stabilized diazonium salts and substituted napthols.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.