With this volume of three essays, the authors want to create an opportunity for dialogue between different disciplines by taking a closer look at three cardio-physiological examples. In the essays presented, we will look at the exploration of different cardiological topics from the 20th century, all of which have contributed to a better understanding of certain aspects of cardiac activity. Not only do these insights provide a more complete picture of these cardiac phenomena, but it is also within this context that we can look for and into the patterns of regularities which govern this living organism. Our goal is to stimulate a dialogue on the philosophy of science in the spirit of Hans Reichenbach.

The volume and complexity of information, together with the number of abstraction levels and the size of data and knowledge bases, grow continually. Data originating from diverse sources involves a combination of data from traditional legacy sources and unstructured data requiring backwards modeling, meanwhile, information modeling and knowledge bases have become important contributors to 21st-century academic and industrial research. This book presents the proceedings of EJC 2023, the 33rd International Conference on Information Modeling and Knowledge Bases, held from 5 to 9 June 2023 in Maribor, Slovenia. The aim of the EJC conferences is to bring together experts from different areas of computer science and from other disciplines that share the common interest of understanding and solving the problems of information modeling and knowledge bases and applying the results of research to practice. The conference constitutes a research forum for the exchange of results and experiences by academics and practitioners dealing with information and knowledge bases. The topics covered at EJC 2023 encompass a wide range of themes including conceptual modeling; knowledge and information modeling and discovery; linguistic modeling; cross-cultural communication and social computing; environmental modeling and engineering; and multimedia data modeling and systems. In the spirit of adapting to the changes taking place in these areas of research, the conference was also open to new topics related to its main themes. Providing a current overview of progress in the field, this book will be of interest to all those whose work involves the use of information modeling and knowledge bases.

Bernard Lonergan identified the need and possibility of what he called 'generalized empirical method' in science and philosophy. Implementation will be a future community achievement. The book enters into details of a selection of examples in the sciences and philosophy of science. These are provided not to engage in, or blend the present aim with traditional philosophical debate, but as points of entry to help reveal the possibility and need of balanced empirical method. Taking words of Lonergan: '(Q)uestions of method are practical. So my purpose in these (chapters) is not to demonstrate what is necessary. It is not to forecast what is probable. It is ... to invite you to share in the exploration of a proposal' (Bernard Lonergan, A Third Collection (1985), 114). The main examples are drawn from biochemistry and biology, although heuristics envisioned will include all sciences.

This book provides a new generation of research in which scholars are investigating mental health and human development as not merely the absence of illness or dysfunction, but also the presence of subjective well-being. Subjective well-being is a fundamental facet of the quality of life. The quality of an individual’s life can be assessed externally and objectively or internally and subjectively. From an objective standpoint, other people measure and judge another’s life according to criteria such as wealth or income, educational attainment, occupational prestige, and health status or longevity. Nations, communities, or individuals who are wealthier, have more education, and live longer are considered to have higher quality of life or personal well-being. The subjective standpoint emerged during the 1950s as an important alternative to the objective approach to measuring individual’s well-being. Subjectively, individuals evaluate their own lives as evaluations made, in theory, after reviewing, summing, and weighing the substance of their lives in social context. Research has clearly shown that measures of subjective well-being, which are conceptualized as indicators of mental health (or ‘mental well-being’), are factorially distinct from but correlated with measures of symptoms of common mental disorders such as depression. Despite countless proclamations that health is not merely the absence of illness, there had been little or no empirical research to verify this assumption. Research now supports the hypothesis that health is not merely the absence of illness, it is also the presence of higher levels of subjective well-being. In turn, there is growing recognition of the personal and social utility of subjective well-being, both higher levels of hedonic and eudaimonic wellbeing. Increased subjective well-being has been linked with higher personal and social ‘goods’: higher business profits, more worker productivity, greater employee retention; increased protection against mortality; increased protection against the onset and increase of physical disability with aging; improved cognitive and immune system functioning; and increased levels of social capital such as civic responsibility, generativity, community involvement and volunteering. This edited volume brings together for the first time the growing scientific literature on positive mental health that is now being conducted in many countries other than the USA and provides students and scholars with an invaluable source for teaching and for generating new ideas for furthering this important line of research.

Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today's advances in pathology and medicine. - Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine - Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology - Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. - Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease - Explains the practice of "molecular medicine and the translational aspects of molecular pathology - Teaches from the perspective of "integrative systems biology - Enhanced digital version included with purchase

Education is a field sometimes beset by theories-of-the-day and with easy panaceas that overpromise the degree to which they can alleviate pressing educational problems. The two-volume Encyclopedia of Educational Theory and Philosophy introduces readers to theories that have stood the test of time and those that have provided the historical foundation for the best of contemporary educational theory and practice. Drawing together a team of international scholars, this invaluable reference examines the global landscape of all the key theories and the theorists behind them and presents them in the context needed to understand their strengths and weaknesses. In addition to interpretations of long-established theories, this work offers essays on cutting-edge research and concise, to-the-point definitions of key concepts, ideas, schools, and figures. Features: Over 300 signed entries by trusted experts in the field are organized into two volumes and overseen by a distinguished General Editor and an international Editorial Board. Entries are followed by cross references and further reading suggestions. A Chronology of Theory within the field of education highlights developments over the centuries; a Reader’s Guide groups entries thematically, and a master Bibliography facilitates further study. The Reader’s Guide, detailed index, and cross references combine for strong search-and-browse capabilities in the electronic version. Available in a choice of print or electronic formats, Encyclopedia of Educational Theory and Philosophy is an ideal reference for anyone interested in the roots of contemporary educational theory.

Introduction to Kinesiology: Studying Physical Activity, Fourth Edition, offers the most cohesive introduction to the field of kinesiology available, giving students a solid background in the field and preparing them for further study and course work.