The book presents the state of the art in the interdisciplinary field of fluid mechanics applied to cardiovascular modelling. It is neither a monograph nor a collection of research papers, rather an extended review in the field. It is arranged in 4 scientific chapters each presenting thoroughly the approach of a leading research team; two additional chapters prepared by biomedical scientists present the topic by the applied perspective. A unique feature is a substantial (approx. one fourth of the book) medical introductory part, written by clinical researchers for scientific readers, that would require a large effort to be collected otherwise.

First Published in 1981, this book offers a full, comprehensive guide to the operation of cardiovascular fluid systems. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for cardiologists, haematologists, students of medicine, and other practitioners in their respective fields.

Cardiovascular Fluid Dynamics, Volume 1 explores some problems and concepts of mammalian cardiovascular function, with emphasis on experimental studies and methods. It considers pressure measurement in experimental physiology, including the measurements of pulsatile flow, flow velocity, lengths, and dimensions; the use of control theory and systems analysis in cardiovascular dynamics; the application of computer models in cardiovascular research; the meaning and measurement of myocardial contractility; and the consequences of the steady-state analysis of arterial function. Organized into 10 chapters, this volume begins with an overview of the mammalian cardiovascular system and the essential features of cardiovascular function. It then discusses the practical problems associated with the use of pressure transducers in physiological and cardiac laboratories, the challenges involved in pulsatile flow measurement using flowmeters and thermal devices, and the mechanical analysis of the circulatory system. It explains some computer modeling techniques used in investigating the hemodynamics of the cardiovascular system, including the heart and heart muscle; basic concepts of muscle mechanics and the mechanical properties of cardiac muscle; the fluid mechanics of heart valves; and the pressure and flow in large arteries. The book concludes with a chapter on vascular resistance and vascular input impedance. This book is intended for biologists, physical scientists, and others interested in cardiovascular physiology.

This book provides a guiding thread between the distant fields of fluid mechanics and clinical cardiology. Well rooted in the science of fluid dynamics, it drives the reader across progressively more realistic scenarios up to the complexity of routine medical applications. Based on the author’s 25 years of collaborations with cardiologists, it helps engineers learn communicating with clinicians, yet maintaining the rigor of scientific disciplines. This book starts with a description of the fundamental elements of fluid dynamics in large blood vessels. This is achieved by introducing a rigorous physical background accompanied by examples applied to the circulation, and by presenting classic and recent results related to the application of fluid dynamics to the cardiovascular physiology. It then explores more advanced topics for a physics-based understanding of phenomena effectively encountered in clinical cardiology. It stands as an ideal learning resource for physicists and engineers working in cardiovascular fluid dynamics, industry engineers working on biomedical/cardiovascular technology, and students in bio-fluid dynamics. Written with a concise style, this textbook is accessible to a broad readership, including students, physical scientists and engineers, offering an entry point into this multi-disciplinary field. It includes key concepts exemplified by illustrations using cutting-edge imaging, references to modelling and measurement technologies, and includes unique original insights.

With the Karlsruhe Heart Model (KaHMo) we aim to share our vision of integrated computational simulation across multiple disciplines of cardiovascular research, and emphasis yet again the importance of Modelling the Human Cardiac Fluid Mechanics within the framework of the international STICH study. The focus of this work is on integrated cardiovascular fluid mechanics, and the potential benefits to future cardiovascular research and the wider bio-medical community.

This text deals with intra and extra-corporeal cardiovascular fluid dynamics. Topics covered include: cardiac mechanical models; analysis of arterial haemodynamics using the principle of wave separation; microvascular networks; cardiac assist devices and others.

Ludwig Prandtl has been called the father of modern fluid mechanics, and this updated and extended edition of his classic text on the field is based on the 12th German edition with additional material included.

This book provides a guiding thread between the distant fields of fluid mechanics and clinical cardiology. Well rooted in the science of fluid dynamics, it drives the reader across progressively more realistic scenarios up to the complexity of routine medical applications. Based on the author's 25 years of collaborations with cardiologists, it helps engineers learn communicating with clinicians, yet maintaining the rigor of scientific disciplines. This book starts with a description of the fundamental elements of fluid dynamics in large blood vessels. This is achieved by introducing a rigorous physical background accompanied by examples applied to the circulation, and by presenting classic and recent results related to the application of fluid dynamics to the cardiovascular physiology. It then explores more advanced topics for a physics-based understanding of phenomena effectively encountered in clinical cardiology. It stands as an ideal learning resource for physicists and engineers working in cardiovascular fluid dynamics, industry engineers working on biomedical/cardiovascular technology, and students in bio-fluid dynamics. Written with a concise style, this textbook is accessible to a broad readership, including students, physical scientists and engineers, offering an entry point into this multi-disciplinary field. It includes key concepts exemplified by illustrations using cutting-edge imaging, references to modelling and measurement technologies, and includes unique original insights.

Designed for senior undergraduate or first-year graduate students in biomedical engineering, Biofluid Mechanics: The Human Circulation, Second Edition teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition has been extensively revised and updated. New to the Second Edition Improved figures and additional examples More problems at the end of each chapter A chapter on the computational fluid dynamic analysis of the human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas Drawing on each author’s experience teaching courses on cardiovascular fluid mechanics, the book begins with introductory material on fluid and solid mechanics as well as a review of cardiovascular physiology pertinent to the topics covered in subsequent chapters. The authors then discuss fluid mechanics in the human circulation, primarily applied to blood flow at the arterial level. They also cover vascular implants and measurements in the cardiovascular system.

Cardiac Dynamics is the name of a relatively young field of study, born from the fruitful interaction between branches of two different disciplines: medicine and physics. "Dynamics" is the branch of physics which deals with the action of forces on bodies or particles in motion or at rest. "Cardiac" relates to the clinical field of cardiology but also to cardiophysiology, both of which are specialized branches of medicine. Narrower than the well established field of Hemodynamics, Cardiac Dynamics is restricted to dynamic phenomena occurring in and around the heart. The mathematical treatment of such phenomena, however, is vastly more complex because of the intricate nature of the mechanisms involved in the cardiac action. Thus, whereas hemodynamics is concerned with predominantly passive (visco-) elastic structures - vessels - containing time-variant flow of viscous flui- blood -, the mechanical study of the heart requires additional con siderations such as: active elastic components representing the contractile mechanism of cardiac muscle, complex geometry and fiber structure in the myocardial wall, autoregulatory mechanisms, and intricate flow patterns associated with valve motion. Viewed in this light it is not surprising that attempts to describe ventricular pump function and to quantify contractile performance have not reached the level of sophistication which is common in e. g. arterial hemodynamics. For the same reason, many of the often simplified approaches to describe ventricular mechanics failed to stand up to more rigorous theoretical, experimental or clinical testing.