Why is understanding causation so important in philosophy and the sciences? Should causation be defined in terms of probability? Whilst causation plays a major role in theories and concepts of medicine, little attempt has been made to connect causation and probability with medicine itself. Causality, Probability, and Medicine is one of the first books to apply philosophical reasoning about causality to important topics and debates in medicine. Donald Gillies provides a thorough introduction to and assessment of competing theories of causality in philosophy, including action-related theories, causality and mechanisms, and causality and probability. Throughout the book he applies them to important discoveries and theories within medicine, such as germ theory; tuberculosis and cholera; smoking and heart disease; the first ever randomized controlled trial designed to test the treatment of tuberculosis; the growing area of philosophy of evidence-based medicine; and philosophy of epidemiology. This book will be of great interest to students and researchers in philosophy of science and philosophy of medicine, as well as those working in medicine, nursing and related health disciplines where a working knowledge of causality and probability is required.

Presents a new approach to causal inference and explanation, addressing both the timing and complexity of relationships.

This is an original book on the philosophy of medicine. It considers philosophy of medicine as a subdiscipline of philosophy of science. This volume is grounded on an epistemological bottom-up account that arises from the clinical situation, the epidemiologic, and the resulting public health account. It is not a review of the literature, and it is not intended to frame the debates, or to analyze and compare the various number of viewpoints. Medicine is the human activity, which begins by a linguistic act that identifies the negative norms of health: it begins with a first distinction that splits biological processes into three conventional parts, normal, abnormal and pathologic. Neither of them is a natural kind. Being abnormal is intrinsically bad and admits of degrees, while being pathologic is dichotomous. Being normal is factitious and counterfactual much the same as frictionless planes in physics. Leaving apart the ethical aspects, this book endeavors to uncover the implicit conceptual network, the chief junctures of medicine, should they be found, and their articulations with clinical and community medicine. It results that medicine is pervaded with dichotomous concepts such as scientific vs pragmatic discourse, function and malfunction, abnormal and pathologic, needs and wants, causation and explanation, clinical vs community-oriented care, physical vs psychiatric diseases, mental illness vs deviancy, and so on. Medical thinking has two dimensions intrinsically interweaved, namely a constant amalgam and admixture of biological and normative aspects, so that this essential hybrid nature of the grammar of medicine endorses opposite approaches, naturalistic or normativist, biological or value-laden, realist or instrumental, reductionist or holistic, phenomenological or analytic.

Causation is an issue that is fundamental in both law and medicine, as well as the interface between the two disciplines. It is vital for the resolution of a great many disputes in court concerning personal injuries, medical negligence, criminal law and coronial issues, as well as in the provision of both diagnoses and treatment in medicine. This book offers a vital analysis of issues such as causation in law and medicine, issues of causal responsibility, agency and harm in criminal law, causation in forensic medicine, scientific and statistical approaches to causation, proof of cause, influence and effect, and causal responsibility in tort law. Including contributions from a number of distinguished doctors, lawyers and scientists, it will be of great interest and value to academics and practitioners alike.

Medical responsibility lawsuits have become a fact of life in every physician’s medical practice. However, there is evidence that physicians are increasingly practising defensive medicine, ordering more tests than may be necessary and avoiding patients with complicated conditions. The modern practice of medicine is increasingly complicated by factors beyond the traditional realm of patient care, including novel technologies, loss of physician autonomy, and economic pressures. A continuing and significant issue affecting physicians and the healthcare system is malpractice. In the latter half of the 20th century, there was a major change in the attitude of the public towards the medical profession. People were made aware of the huge advances in medical technology, because health problems increasingly tended to attract media interest and wide publicity. Medicine is a victim of its own success in this respect, and people are now led to expect the latest techniques and perfect outcomes on all occasions. This burst of technology and hyper-specialization in many fields of medicine means that each malpractice claim is transformed into a scientific challenge, requiring specific preparation in analysis and judgment of the clinical case in question. The role of legal medicine becomes more and more peculiar in this judicial setting, often giving rise to erroneous interpretations and hasty scientific verdicts, but guidelines on the methodology of ascertainments and criteria of evaluation are lacking all over the world.The aim of this volume is to clarify the steps required for sequential in-depth analysis of events and consequences of medical actions, in order to verify whether, in the presence of damage, errors or non-observance of rules of conduct by health personnel exist, and which causal values and links of their hypothetical misconduct are involved.​

This book provides detailed concepts and information on principles and processes of signal analysis in pharmacovigilance along with case studies. It covers the fundamental concepts and principles of pharmacovigilance, emphasizing the need for robust signal detection and analysis methods. The book reviews the diverse array of databases and tools employed for signal detection, including electronic health records (EHRs), social media mining, claims data, and distributed data networks. In turn, the book discusses the application of molecular dynamics, molecular docking, and the use of the FDA Adverse Event Reporting System (FAERS) database in signal analysis. Toward the end, the book explores the identification, validation, and assessment of signals associated with vaccines. This book is useful for graduate, post-graduate students of pharmaceutical sciences, and scientists in pharmacology research and drug development.

On May 13-15, 1982, some 50 scientists and scholars - physicians, philos ophers and social scientists - convened at Hasselby Castle in Stockholm for the first Nordic Symposium on the Philosophy of Medicine. The topics for the symposium included (1) the concepts of health and disease, (2) classification in medicine, and (3) causality and causal explanations in medicine. The majority of the participants were Scandinavian but the symposium was also able to welcome four distinguished guests from other parts of the world, Professors Stuart F. Spicker and H. Tristram Engelhardt, Jr., U.S.A., Dr Anne M. Fagot, France, and Dr Werner Morbach, West Germany. The latter represented Professor Kazem Sadegh-zadeh, who unfortunately was prevented from attending. One of the main purposes of this symposium was to bring together people in Scandinavia who at present work within the field of Philosophy of Medi cine. This group is still relatively small but is growing rapidly, and the scholarly activity has recently been notable. This fact is clearly demonstrated by the presentation of 'Philosophy of Medicine in Scandinavia' in the Appendix of this volume.

Practical Data Analytics for Innovation in Medicine: Building Real Predictive and Prescriptive Models in Personalized Healthcare and Medical Research Using AI, ML, and Related Technologies, Second Edition discusses the needs of healthcare and medicine in the 21st century, explaining how data analytics play an important and revolutionary role. With healthcare effectiveness and economics facing growing challenges, there is a rapidly emerging movement to fortify medical treatment and administration by tapping the predictive power of big data, such as predictive analytics, which can bolster patient care, reduce costs, and deliver greater efficiencies across a wide range of operational functions. Sections bring a historical perspective, highlight the importance of using predictive analytics to help solve health crisis such as the COVID-19 pandemic, provide access to practical step-by-step tutorials and case studies online, and use exercises based on real-world examples of successful predictive and prescriptive tools and systems. The final part of the book focuses on specific technical operations related to quality, cost-effective medical and nursing care delivery and administration brought by practical predictive analytics. Brings a historical perspective in medical care to discuss both the current status of health care delivery worldwide and the importance of using modern predictive analytics to help solve the health care crisis Provides online tutorials on several predictive analytics systems to help readers apply their knowledge on today’s medical issues and basic research Teaches how to develop effective predictive analytic research and to create decisioning/prescriptive analytic systems to make medical decisions quicker and more accurate

Veterinary Pharmacovigilance: Adverse Reactions to Veterinary Medicinal Products is an in-depth examination of veterinary pharmacovigilance, looking at the scientific methodologies involved, the role of regulatory agencies and legislation, and the underpinning science. Edited by a renowned expert with over 20 years of experience in the field, it draws together the expertise of authors from around the world.

The present volume is about philosophy of medicine and integrates philosophy of medicine as a chapter of philosophy of science. It is neither about bioethics, nor about the history of medicine, but it is comprehensive and encompasses the whole field of medicine including psychiatry. It is grounded on a first-order standpoint, and it strives to stay close to clinical or community medicine: it bestows an epistemological bottom-up account. It is not a review of the literature, and it is not intended to frame the debates, or to analyse and compare the various and substantial number of viewpoints although some authors’ account may form the basis of the book when they fit into the development of its philosophical view of medicine.