The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells

Nanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology. Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments. It is divided into four main sections: * Interphase Systems * Protein-based Nanostructures * DNA-based Nanostructures * Nanoanalytics Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.

This book is a printed edition of the Special Issue "Yeast Biotechnology" that was published in Fermentation

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials' community. - The most comprehensive coverage of principles and applications of all classes of biomaterials - Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials - Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. - Online chapter exercises available for most chapters

An authoritative introduction to the science and engineering of bioinspired materials Bioinspired Materials Science and Engineering offers a comprehensive view of the science and engineering of bioinspired materials and includes a discussion of biofabrication approaches and applications of bioinspired materials as they are fed back to nature in the guise of biomaterials. The authors also review some biological compounds and shows how they can be useful in the engineering of bioinspired materials. With contributions from noted experts in the field, this comprehensive resource considers biofabrication, biomacromolecules, and biomaterials. The authors illustrate the bioinspiration process from materials design and conception to application of bioinspired materials. In addition, the text presents the multidisciplinary aspect of the concept, and contains a typical example of how knowledge is acquired from nature, and how in turn this information contributes to biological sciences, with an accent on biomedical applications. This important resource: Offers an introduction to the science and engineering principles for the development of bioinspired materials Includes a summary of recent developments on biotemplated formation of inorganic materials using natural templates Illustrates the fabrication of 3D-tumor invasion models and their potential application in drug assessments Explores electroactive hydrogels based on natural polymers Contains information on turning mechanical properties of protein hydrogels for biomedical applications Written for chemists, biologists, physicists, and engineers, Bioinspired Materials Science and Engineering contains an indispensible resource for an understanding of bioinspired materials science and engineering.

Stem cell research is one of the leading "cutting edge" areas of life science research in the world today and is a topic of significant interest to a broad range of the medical and scientific community. This authoritative book provides reviews by the field's leading scientists and covers many of the areas in which stem cells are becoming increasingly important, such as in organ repair and regeneration. Stem cells offer the possibility of cell therapy issues to treat a myriad of diseases, conditions, and disabilities including Parkinson's and Alzheimer's diseases, spinal cord injury, stroke, heart disease, and diabetes.

Autonomous Positioning of Piezoactuated Mechanism for Biological Cell Puncture gives a systematic and almost self-contained description of the many facets of advanced design, optimization, modeling, system identification, and advanced control techniques for positioning of the cell puncture mechanism with a piezoelectric actuator in micro/nanorobotics systems. To achieve biomedical applications, reliability design, modeling, and precision control are essential for developing engineering systems. With the advances in mechanical design, dynamic modeling, system identification, and control techniques, it is possible to expand the advancements in reliability design, precision control, and quick actuation of micro/nanomanipulation systems to the robot’s applications at the micro- and nanoscales, especially for biomedical applications. This book unifies existing and emerging techniques concerning advanced design, modeling, and advanced control methodologies in micropuncture of biological cells using piezoelectric actuators with their practical biomedical applications. The book is an essential resource for researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts. KEY FEATURES • Provides a series of latest results in, including but not limited to, design, modeling, and control of micro/nanomanipulation systems utilizing piezoelectric actuators • Gives recent advances of theory, technological aspects, and applications of advanced modeling, control, and actuation methodologies in cell engineering applications • Presents simulation and experimental results to reflect the micro/nano manipulation practice and validate the performances of the developed design, analysis, and synthesis approaches

Plants are made up of a large number of distinct cell types that originate from a single fertilized egg cell. How the diversity of cell types arise in appropriate places is one of the most fascinating and attractive research areas of plant biology. During the past several decades, due to the development of new molecular techniques and tools, advances in optical microscopy, and availability of whole genome information and mutants in the model plant Arabidopsis and other plants, great advances have been made in understanding the mechanisms involved in cell fate determination in plants. Multiple mechanisms are used to generate cellular diversity. Asymmetric cell division is one of the primary mechanisms. As an example, asymmetric cell division enables one stem cell to generate a stem cell daughter and a daughter with a distinct identity. Initially equivalent cells can also differentiate to generate different cell types. This mechanism has been clearly demonstrated in the formation of multiple cell types during epidermis development in the shoot and root. Cell fate determination is influenced by both intrinsic factors, i.e, developmental regulators, as well as extrinsic signals, i.e., environmental stimuli. By using model systems like stomata, trichome, root hair and shoot and root apical meristem cells, ligands, receptors and transcription factors have been found to regulate cell fate determination. However, the details of signaling cassettes responsible for cell fate determination remain largely unknown. Plants are made up of a large number of distinct cell types that originate from a single fertilized egg cell. How the diversity of cell types arise in appropriate places is one of the most fascinating and attractive research areas of plant biology. During the past several decades, due to the development of new molecular techniques and tools, advances in optical microscopy, and availability of whole genome information and mutants in the model plant Arabidopsis and other plants, great advances have been made in understanding the mechanisms involved in cell fate determination in plants. This research topic contains 12 collected articles, including 2 Opinion Articles, 5 Reviews, 4 Mini Reviews, and 1 Original Research Article. Hopefully, these articles will expand our understanding of the regulation of cell fate determination in plants.