With chapter contributions from more than 30 metal biology experts, Cellular and Molecular Biology of Metals explains the role of key divalent metal ions involved in the molecular and cellular biology of various target cell populations. Although it primarily focuses on homeostatic metals, such as nickel, zinc, and chromium, the text also discusses

International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. This most current release in this highly cited series focuses on such timely topics as novel treatments in immunotherapy in breast cancer, chemokine receptor signaling and the hallmarks of cancer, tumor-targeting antibodies, and a section on mitochondrion and whether they are a common organelle for cell death. As always, readers will find the articles in this series to be of great value, with a high impact and average cited half-life of nine years. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This great resource ranks high amongst scientific journals dealing with cell biology. - Publishes only invited review articles on selected topics - Authored by established and active cell and molecular biologists, drawn from international sources - Offers a wide range of perspectives on specific subjects

One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.

This much-needed book is the first definitive volume on Euglena in twenty-fire years, offering information on its atypical biochemistry, cell and molecular biology, and potential biotechnology applications. This volume gathers together contributions from well-known experts, who in many cases played major roles in elucidating the phenomenon discussed. Presented in three parts, the first section of this comprehensive book describes novel biochemical pathways which in some instances have an atypical subcellular localization. The second section details atypical cellular mechanisms of organelle protein import, organelle nuclear genome interdependence, gene regulation and expression that provides insights into the evolutionary origins of eukaryotic cells. The final section discusses how biotechnologists have capitalized on the novel cellular and biochemical features of Euglena to produce value added products. Euglena: Biochemistry, Cell and Molecular Biology will provide essential reading for cell and molecular biologists with interests in evolution, novel biochemical pathways, organelle biogenesis and algal biotechnology. Readers will come away from this volume with a full understanding of the complexities of the Euglena as well as new realizations regarding the diversity of cellular processes yet to be discovered.

Molecular Biology and Toxicology of Metals provides a critical review and analysis of the current state of knowledge of metal ion transport and metabolism in prokaryotic and eukaryotic cellular systems. It covers the latest information on specific metals and the biological molecules with which metals interact. It also details mechanisms in the handling and toxicity of metals in specific organ systems, and the role of metals in cell signalling and gene transcription in target cells. This book is sure to prove a fertile meeting ground for the disciplines of molecular genetics and metal toxicology.

The brine shrimp Artemia has become an important experimental system for studies of the developmental process. In recent years the shrimp has yielded considerable information on the pattern of development, bio chemistry, and gene structure and expression of crustaceans. This book is a compilation of research activity from twenty five of the most active re search laboratories working with brine shrimp in the above areas. It also represents the proceedings of a NATO Advanced Research Workshop held in Montreal, Canada, August 11-13, 1988. The book contains twenty nine full papers covering the major areas discussed at the workshop. In addition, one page abstracts representing seventeen poster presentations which were given at the workshop, and which were deemed to be most relevant to the theme of the book, are included. These are designated with an [al in the Table of Contents following the title of each paper. A considerable amount of discussion which took place during the workshop has not been included in the book because of space limitations. However, the editors will endeavour to make some of this in formation available at a later date through the Artemia Newsletter. In addition to the high percentage of invited speakers who attended and contributed to the workshop, the organizers would like to thank a number of participants who made valuable contributions to the major dis cussion sessions. These include: John Freeman, Michael Horst, Herman Slegers, Jack Vaughn, Frank Conte, Sandy McLennan, Clive Trotman and Patrick Sorgeloos.

The Volume 2 of the treatise on the Developments in Physiology, Biochemistry and Molecular Biology of Plants provides additional information in the crucial areas for making precise and applied research in the national context, on the one hand, and to unravel the science, on the other hand. In the earlier volume, the theme of publishing this needful treatise has been already made obvious. However, in view of the experiences and enormous advances in plant science research in the last few decades providing enough insight to scan vital research in this century has, almost certainly, enlightened the path to undertake necessary research projects for the benefit of mankind to which we are indispensably committed. We, the plant physiologists, biochemists, molecular biologists and plant nutritionists must be proud of our support to the world's farmers which has helped them make their achievement possible. In this century, up to 2025, the human population is expected to double and that is in truth a serious issue for us to trace out the limiting factors reducing yield potentiality of crop plants, on the one hand, and to understand the science of related processes at different levels, alternatively. This principally necessitates for elucidation of dimensions of environmental stresses in relation to crop plants and their genotypes, optimally suitable to prevailing stress conditions. Of course, in the last few decades more emphasis was laid in this direction and remarkable progress has been made at the global scale to meet the challenges. Owing to this, distinguished scientists have been consistently reviewing and synchronizing the manifold research and signifying specific research of basic and applied implication in classified segment. It is delightful to mention that our attempt to sufficiently provide the essential and comprehensive literature to speed up important research in explicit areas of plant sciences has been once again tremendously satisfactory due to exceptional dedication of illustrious Indian scientists in the preparation of this momentous work. This treatise has been ordered with twelve excellent contributions in the form of review articles by thirty well- known Indian workers and academicians. The reviews are relevant to guide for theme oriented research as well as for scientific future planning of research projects. The four applicable sections related to: I. Sustainable Crop Productivity, II. Recent Advances in Plant Metabolism; III. Molecular Physiology of Plants; IV. Environmental Stresses in Plants consist of over twelve meaningful review articles as substantial chapteMoreover, as promised, prominence has been given to compile extremely important aspects of Stress Physiology. The detailed choice of the contents of the various contributions has been left largely to the individual authoDoubtless, this book will be of immense help to scientists, teachers and students of almost all disciplines of Agriculture, Botany and Biotechnology.

The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter reviews key terms, tests for understanding basic concepts, and poses research-based problems. The Problems Book has be

Karp continues to help biologists make important connections between key concepts and experimentation. The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field. The book also builds on its strong illustration program by opening each chapter with “VIP” art that serves as a visual summary for the chapter. Over 60 new micrographs and computer-derived images have been added to enhance the material. Biologists benefit from these changes as they build their skills in making the connection.

This new edition provides a comprehensive look at the molecular genetics and biochemical basis of fungal biology, covering important model organisms such as Aspergilli while also integrating advances made with zygomycetes and basidiomycetes. This book groups a total of 15 chapters authored by expert scholars in their respective fields into four sections. Five chapters cover various aspects of gene expression regulation. These range from regulation in organismal interactions between parasitic fungi and their host plant, heavy metal stress and global control of natural product genes to conidiation and regulation through RNA interference. Two chapters are dedicated to signal transduction, highlighting MAP-kinase-dependent signaling and heterotrimeric G-proteins. Fungal carbohydrates are the subject of the third section, which addresses both polymeric cell wall carbohydrates and trehalose as an important, low molecular weight carbohydrate. The fourth section emphasizes the metabolism of major elements (carbon, nitrogen, sulfur) and critical cellular pathways for primary and secondary products.