Central neurocytoma is a tumor of young adults composed of uniform round cells with neuronal differentiation, typically occurring in the lateral ventricles in the region of the foramen of Monro. Neurocytomas is a hot topic in neuro oncology especially with modern developments of radiation and novel chemotherapy agents.

This issue provides a glimpse into how pain can be assessed and managed by several medical disciplines and approaches. It covers classical and conventional techniques as well as innovative techniques.

The evidence-based medicine movement is gaining influence in many medical specialties. This issue will cover topics from patient safety in neurosurgery and medical errors, to measuring outcomes for neurosurgical procedures.

This issue will cover chiari malformation in both children and adult populations. In the past, it was estimated that the condition occurs in about one in every 1,000 births. However, the increased use of diagnostic imaging has shown that CM may be much more common. Complicating this estimation is the fact that some children who are born with the condition may not show symptoms until adolescence or adulthood, if at all. CMs occur more often in women than in men and Type II malformations are more prevalent in certain groups, including people of Celtic descent.

This issue serves as a high-level topic review and keeps the readers updated on current and future neurointervention directions.

Because the base of the skull has proven to be one of the most challenging regions of the body to access, treatment options were once limited for patients with tumors or lesions in this area. However, with recent advancements and breakthroughs in treatment, patients with skull base tumors now have an array of surgical options that can help them return to leading a normal and active life. The Endoscopic Endonasal Approach (EEA) is an innovative surgical technique used to remove brain tumors and lesions—some as large as softballs—all through the nose.

This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis – evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases – diagnosis and management, and more.

Epidemiology of Endocrine Tumors brings current data and clinical research into one source for a multidisciplinary audience. The book discusses the prevalence, incidence, etiology, pathology, diagnosis and treatment of various endocrine tumors. With clear and focused writing, it is essential reading for healthcare professionals, endocrinologists, oncologists, and public health professionals. Users will be able to bridge the knowledge gap that exists in the comprehensive coverage surrounding the epidemiology of endocrine tumors. Globally, the prevalence and incidence of endocrine tumors is high. This audience needs a treatise where they can gain a broad overview of endocrine tumors with a focus on epidemiology. - Supplies information about the epidemiology of various endocrine tumors, both benign and malignant, to endocrinologists, oncologists and related health care professionals - Focuses on the impact upon costs and patient deaths due to complications of these tumors - Describes how endocrine tumors affect various age groups and ethnicities, discussing the prevention of endocrine tumors - Presents chapters on Cancer Problem, Specific Endocrine Tumors, Prevention, Detection and Diagnosis, and Treatment of Endocrine Tumors - Provides review questions with an answer key and detailed glossary

Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors addresses limitations in the scientific literature by focusing primarily on surgical approaches to various intrinsic neoplasms using diagrams and step-by-step instructions. It provides the advantages and disadvantages of these approaches, controversies, and technical considerations and discusses topics such as anatomy, pathology and animal models, imaging, open brain tumor approaches and minimally invasive approaches. Additionally, it discusses controversial treatments and the pros and cons of each. This book is a valuable source for medical students, neurosurgeons and any healthcare provider who has an interest in brain tumors and techniques to treat them.

This issue of MRI Clinics focuses on Advances in Diffusion-weighted Imaging and is edited by Dr. Kei Yamada. Articles will include: Technical Basics of Diffusion-weighted Imaging; Neurofluid as Assessed by Diffusion-weighted Imaging; Diffusion-weighted Imaging is the Key to Diagnoses; Diffusion-weighted Imaging of the Spinal Cord; Intracranial Abnormalities with Diffusion Restriction; Brain Anatomy by Diffusion-weighted Imaging; Measuring Perfusion: Intravoxel Incoherent Motion; Temperature Measurement by Diffusion-weighted Imaging; Diffusion-weighted Imaging at Ultra-high Field MRI; Diffusion-weighted Imaging for Radiomics; Diffusion Weighted Imaging for Infants; Diffusion-weighted Imaging of the Head and Neck (Including Temporal Bone); DTI, DKI and Q-space Imaging; and more!