Providing the inside track on how the experts approach and deal with real-world clinical scenarios, Challenging Concepts In Oncology selects twenty five cases to highlight the important issues relating to common cancers and common cancer-related complications, which do not have simple answers. Each case discusses the presentation of the cancer, its treatment, and an acute oncological emergency. Written using the UK Oncology curricula for Medical Oncology and Clinical Oncology to support preparation for the MRCP3 examination in Medical Oncology and FRCR, Challenging Concepts in Oncology highlights critical information through the use of boxed features: 'Learning points', 'Clinical tips', and 'Evidence base'. Each chapter has been reviewed by a national or international expert in the field and they have provided an 'Expert commentary', giving a unique insight into how today's opinion leaders confront and deal with the challenges that all oncologists can potentially face on a daily basis. Aimed primarily at specialty trainees and registrars in oncology, this text is also a valuable resource for all health care professionals involved in looking after patients with cancer in primary, secondary, and tertiary care. It is also a fantastic resource for undergraduates who want to find out more about oncology.

This is a case-based guide to difficult scenarios faced in the fields of obstetrics and gynaecology. Each case is set off by an 'Expert Commentary' written by an expert, giving the reader both a solid base of knowledge and a nuanced view of current challenges.

Providing the inside track on how the experts approach and deal with real-life clinical scenarios, Challenging Concepts in Paediatric Critical Care explores eighteen common, complex and often contentious topics seen in hospitals, high dependency units, and PICU's worldwide. These include cases on 'Paediatric acute respiratory distress syndrome', 'Traumatic brain injury', and 'Safeguarding children in paediatric intensive care'. With a case-based approach, complex patient presentations are explored thoroughly so that assessment, diagnosis, and management are fully considered and explored with 'Clinical Tips', 'Learning Points', and 'Evidence Base' boxes. Throughout commentary from an international expert identifies and explains the key points and controversies of each case. Aligned to the Royal College of Paediatrics and Child Health's paediatric intensive care medicine curriculum in the UK, the curriculum of Paediatric Basic Assessment and Support in Intensive Care (BASIC) course, and the European Paediatric/ Neonatal Intensive Care Diploma (EPIC), this text is ideal for training and assessment preparation. Aimed primarily at trainees and registrars in paediatric intensive care medicine, this text will appeal to those in the related disciplines of anaesthesia, emergency medicine, and paediatrics, as well as consultants and senior nurses.

Genomic sequencing technologies have augmented the classification of cancer beyond tissue of origin and towards a molecular taxonomy of cancer. This has created opportunities to guide treatment decisions for individual patients with cancer based on their cancer’s unique molecular characteristics, also known as precision cancer medicine. The purpose of this text will be to describe the contribution and need for multiple disciplines working together to deliver precision cancer medicine. This entails a multi-disciplinary approach across fields including molecular pathology, computational biology, clinical oncology, cancer biology, drug development, genetics, immunology, and bioethics. Thus, we have outlined a current text on each of these fields as they work together to overcome various challenges and create opportunities to deliver precision cancer medicine. As trainees and junior faculty enter their respective fields, this text will provide a framework for understanding the role and responsibility for each specialist to contribute to this team science approach.

Details 26 complex scenarios relevant to trainees in oral and maxillofacial surgery and related specialties, presenting case histories, alongside learning points and clinical tips for the reader. Each case is accompanied by an overall synopsis and commentary by an expert in the field.

Cancer Stem Cells covers a wide range of topics in cancer stem cell biology, including the functional characteristics of cancer stem cells and how they're generated, where they are localized, the means by which cancer stem cells can be targeted, and how cancer stem cells can be reprogrammed back to normal tissue stem cells. Each chapter begins with a brief historical note and concept summary, followed by a description of the latest basic or clinical advance associated with the topic. Cancer Stem Cells builds systematically from coverage of the basic research stage to an advanced research level, from clinical relevance to therapeutic potential, and will be a valuable resource for professionals in the fields of cancer research and stem cell biology.