This interdisciplinary book consists of the proceedings of the Alexander Ivanovich Oparin lOOth Anniversary Conference, The Third Trieste Conference on Chemical Evolution, which took place at the International Centre for Theoretical Physics from 29 August till 2 September, 1994. A general overview of Oparin's life and work is followed by a review of Alfonso Herera, another pioneer in the studies of the origin of life. The subject matter is organized in ten sections corresponding to various aspects of our current understanding of the subject that was initiated by Oparin. These subjects were covered by fifty three speakers. There were sixty seven participants from a wide geographical distribution; twenty seven countries were represented. We have included the invited lecture of Professor Igor Kulaev, who was unable to be present at the conference for reasons beyond his control. The conference was generously supported by the International Centre for Theoretical Physics, the Commission of the European Communities, the International Centre for Genetic Engineering and Biotechnology, the International Centre for Science and High Technology, and UNESCO. Cyril Ponnamperuma, University of Maryland, U.S.A. Julian Chela-Flores, ICTP, Italy, and IDEA, Venezuela. xi FOREWORD As this volume was going to press we learnt of the untimely death of Cyril Ponnamperuma who died of cardiac arrest on December 20, 1994.

Leading researchers in the area of the origin and evolution of life in the universe contributed to Chemical Evolution: Physics of the Origin and Evolution of Life. This volume provides a review of this interdisciplinary field. In 35 chapters many aspects of the origin of life are discussed by 90 authors, with particular emphasis on the early paleontological record: physical, chemical, biological, and informational aspects of life's origin, instrumentation in exobiology and system exploration; the search for habitable planets and extraterrestrial intelligent radio signals. This book contains the proceedings of the Fourth Trieste Conference on Chemical Evolution that took place in September 1995, in which scientists from a wide geographical distribution joined in a Memorial to Cyril Ponnamperuma, who was a pioneer in the field of chemical evolution, the origin of life, and exobiology, and also initiated the Trieste Conferences on Chemical Evolution and the Origin of Life. This fourth Conference was therefore dedicated to his memory. Audience: Graduate students and researchers in the many areas of basic, earth, and life sciences that contribute to the study of chemical evolution and the origin of life.

Proceedings of the Sixth Trieste Conference on Chemical Evolution, Trieste, Italy, 18-22 September 2000

A Second Genesis enquires why nature is intelligible. The fast growth of technology and deeper understanding of the humanities have provided significant clues. Answering the question why nature can be understood requires an introduction to the new science of astrobiology and the exploration of the Solar System. A careful discussion of a OC second GenesisOCO is presented, namely our present awareness that life may have emerged on other worlds. Writing this volume has been motivated by the need to encourage a constructive dialogue between science and faith. Such an objective for a new book is timely, since science is inserted with well-defined frontiers in the context of human culture. Similarly, the frontiers of faith do not require religion to justify itself in scientific terms, avoiding current unnecessary controversies."

Astrobiology is a very broad interdisciplinary field covering the origin, evolution, distribution, and destiny of life in the universe, as well as the design and implementation of missions for solar system exploration. A review covering its complete spectrum has been missing at a level accessible even to the non-specialist. The last section of the book consists of a supplement, including a glossary, notes, and tables, which represent highly condensed `windows' into research ranging from basic sciences to earth and life sciences, as well as the humanities. These additions should make The New Science of Astrobiology accessible to a wide readership: scientists, humanists, and the general reader will have an opportunity to participate in one of the most rewarding activities of contemporary culture.

How did life begin on the early Earth? We know that life today is driven by the universal laws of chemistry and physics. By applying these laws over the past ?fty years, en- mous progress has been made in understanding the molecular mechanisms that are the foundations of the living state. For instance, just a decade ago, the ?rst human genome was published, all three billion base pairs. Using X-ray diffraction data from crystals, we can see how an enzyme molecule or a photosynthetic reaction center steps through its catalytic function. We can even visualize a ribosome, central to all life, translate - netic information into a protein. And we are just beginning to understand how molecular interactions regulate thousands of simultaneous reactions that continuously occur even in the simplest forms of life. New words have appeared that give a sense of this wealth of knowledge: The genome, the proteome, the metabolome, the interactome. But we can’t be too smug. We must avoid the mistake of the physicist who, as the twentieth century began, stated con?dently that we knew all there was to know about physics, that science just needed to clean up a few dusty corners. Then came relativity, quantum theory, the Big Bang, and now dark matter, dark energy and string theory. Similarly in the life sciences, the more we learn, the better we understand how little we really know. There remains a vast landscape to explore, with great questions remaining.

This work deals with the efforts of creationists during the twentieth and twenty-first centuries to eliminate or limit the teaching of evolution in United States public schools and the response that these efforts generated from mainstream law, science, and religion. The confrontations that ensued often resulted in political maneuvering, the enactment of laws, and litigation. Usually, the litigation found its way into the federal courts with United States constitutional implications. No other scientific theory has ever been subject to such legal prohibition or judicial scrutiny in the history of the United States. Astonishingly, twice, evolution cases of this kind found their way to the Supreme Court. The interplay among the scientific, legal, and religious issues woven throughout the various court decisions that are examined in this work are of particular interest; as is the nature of science. Also, of interest is how proponents of both evolution and creationism cynically altered and bent their arguments in response to prior court decisions in an effort to successfully promulgate their particular position and how courts often tailored their decisions to ideology, rather than judicial principles. A story with scientific, political, and ethical implications is told in this work using a cluster of federal court cases that fairly represent the issues that are at stake in this controversy. Perhaps they also provide us with a model for better understanding how the judicial and legal systems operate.

The origin of life has been investigated by many researchers from various research fields, such as Geology, Geochemistry, Physics, Chemistry, Molecular Biology, Astronomy and so on. Nevertheless, the origin of life remains unsolved. One of the reasons for this could be attributed to the different approaches that researchers have used to understand the events that happened on the primitive Earth. The origins of the main three members of the fundamental life system, as gene, genetic code and protein, could be only separately understood with these approaches. Therefore, it is necessary to understand the origins of gene, the genetic code, tRNA, metabolism, cell structure and protein not separately but comprehensively under a common concept in order to understand the origin of life, because the six members are intimately related to each other. In this monograph, the author offers a comprehensive hypothesis to explain the origin of life under a common concept. At the same time, the author offers the [GADV] hypothesis contrasting it with other current hypotheses and discusses the results of analyses of genes/proteins and the experimental data available in the exploration of the current knowledge in the field. This book is of interest for science students, researchers and the general public interested in the origin of life.

Since the publication of The New Science of Astrobiology in the year 2001—the first edition of the present book—two significant events have taken place raising the subject from the beginning of the present century to its present maturity. Firstly, in 2001 the Galileo Mission still had two years to complete its task, which turned out to be an outstanding survey of the Jovian system, especially of its intriguing satellite Europa. Secondly, the Cassini Huygens Mission was still on its way to Saturn. Its present success has surpassed all expectations of ESA and NASA. Astrobiologists still did not know that Titan was the fifth body in the Solar System that possibly contained a water ocean (including the Earth and the three Galilean satellites other than Io). For these reasons the book includes overviews of the evolutionary and molecular biology that are necessary. There is a discussion of other sectors of culture that are the natural frontiers of astrobiology, especially the humanities.