Much has been said about managing herpesvirus infections since the discovery of acyclovir more than 15 years ago. This book aims to bring practical advice to the key clinician who is faced with managing these infections. It addresses questions like: there are antiviral treatments for many of these infections, but who should be getting these drugs and who should not? What are the advantages, if any, of the new drugs over the old ones? Which patients should be targeted for intervention? What is the clinical reality of antiviral resistance? Where do the up and coming vaccines fit into the picture? When should therapy be discontinued or reassessed? How are patients presenting other than chorioretinitis in AIDS or pneumonitis in transplantation? The contributing clinician scientists deal with these questions and many more. Listed by Biological Abstracts/RRM, BIOSIS, volume 48, issue 8, August 1995 Covered by Current Contents, Life Sciences (ISI), volume 39, no. 2, Januari 1996, p. 12

Widely used by students, residents, generalists, and specialists, Netter's Infectious Diseases, 2nd Edition delivers must-know information on infectious diseases in a highly illustrated, easily accessible format. Concise visual overviews of essential topics provide a convenient, trustworthy way to review the basics of a given infectious disease or issue or to share with patients or staff. Drs. Elaine Jong and Dennis Stevens cover the wide spectrum of illness and disease in this complex field using memorable illustrations by world-renowned artist Frank H. Netter and others, offering a time-saving, authoritative look at infectious disease risk factors, clinical presentations, pathophysiology, and more. - Covers major conditions and problems such as vaccine-preventable diseases, drug-resistant staph, community acquired pneumonia, surgical infections, pyelonephritis, viral hepatitis, and sexually transmitted infections—and provides updated approaches to diagnosis, treatment, prevention, and standards of care. - Includes new clinical vignettes added to most chapters - Provides updated and expanded coverage of emerging infectious diseases such as multidrug resistant tuberculosis (MDR-TB), neuroangiostrongyliasis (rat lungworm disease), Ebola virus, Severe Acute Respiratory Disease (SARS), Middle East Respiratory Syndrome (MERS), Coronavirus Infectious Disease-2019 (COVID-19), and novel influenza viruses including public health concerns. - Covers vector-borne diseases including malaria, yellow fever, Zika infections and congenital Zika syndrome, West Nile fever, Lyme disease, tick-borne encephalitis, and Chagas disease plus others. - New chapters on travelers' diarrhea, cholera, and primary amebic meningoencephalitis debut in the section on international travel and outdoor activities. - Contains memorable parasite life cycles and unforgettable parasite infection clinical vignettes. - Features unparalleled illustrations by Drs. Frank H. Netter, Carlos Machado, and others, as well as radiologic images. - Provides 24 printable patient education brochures in the digital ebook.

Completely revised and updated, Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition, delivers a contemporary and thorough review of HHV-6, beginning with foundational explorations of classification, molecular biology, and chromosomal integration of the virus, through to clinical details, including pathologic features of infection, and clinical effects on various organ systems. The work now includes coverage of HHV-7, a virus that remains underestimated in transplant reactivation, seizures, and encephalitis. The book examines the role of HHV-6 in myriad diseases, including cognitive disorders following bone marrow transplant, mesial temporal lobe epilepsy, multiple sclerosis, autoimmune disease, encephalitis, Hodgkin's disease lymphoma (HHV-6B), and glioma (HHV-6A). Descriptions of current and novel molecular and serological diagnostic assays, along with detailed protocols, are included to aid researchers and clinicians in discriminating potential false positives originating from chromosomally integrated HHV-6, and in differentiating between active and latent infection. Human Herpesviruses HHV-6A, HHV-6B & HHV-7, Third Edition is a valuable reference for both clinical and basic scientists, including epidemiologists, virologists, practicing clinicians, infectious disease specialists, pathologists, and all scientists entering the field of herpes virus research. The work is a practical and thorough resource for a foundational understanding of HHV-6 and HHV-7, while providing a cutting-edge translational and clinical reference to those looking to understand and diagnose associated viral diseases. - Delivers the latest molecular diagnostic tests, the present-day gold standard for monitoring HHV-6 - Provides expert analysis of T-cell immune response against HHV-6 - Presents tools for differential diagnosis in HHV-6 viral infections - Includes new information on the previously-largely-unknown biological consequences of ciHHV-6 - Offers coverage of new discoveries relating to HHV-7

Herpes zoster (shingles) is a serious neurocutaneous disease caused by a reactivation of latent varicella-zoster virus (VZV). It has been underestimated in terms of its burden, particularly in the elderly population and in immunocompromised patients, who

The relationship between herpesviruses and humans probably dates from thousands of years ago. In the last few decades, many aspects of herpesvirus infections have been understood, such as infections with a range of manifestations (severe, mild, or subclinical). Herpesvirus can remain latent during a lifetime and sometimes their reactivation can cause different clinical features in the patient. Several conditions have been related to herpesvirus reactivation such as complications in transplant organ recipients and immune regulatory modification in the elderly. Aspects of human herpesvirus simples, varicella-zoster virus, and cytomegalovirus are presented and discussed in this book.

Handbook of Animal Models of Infection is a complete revision of a three-volume text that was published in 1986. It incorporates the major advances in the field during the past decade, in particular those concerning molecular biological procedures and new models that have been developed. It focuses on both methods and techniques, which makes it an essential and comprehensive reference as well as a benchtop manual. The Handbook will help investigators save time and effort in formulating an approach to test a new potential therapeutic agent or combination of agents for in vivo efficacy and to position the therapy for specific infections where it may have therapeutic promise. The book is divided into five sections; the first covering the general methodologies, followed by sections describing experimental bacterial, mycotic, parasitic, and viral infections. - Discusses ethical and safety aspects in an introductory background section - Covers principles of animal care and current techniques appropriate for the use of animal models of infection - Details a wide range of animals including rodents, rabbits, cats, and primates - Provides hands-on descriptions of how to set up the model - Discusses the major advantages and limitations of each model - Ensures full coverage of bacterial, fungal, viral, and parasitic infections

Readers of Kumar & Clark's Clinical Medicine have consistently requested a handbook with the essentials for medical management and therapeutics, and this new handbook concentrates on the therapeutic side of what procedures to perform, how and - critically - why. Written by young doctors at the forefront of healthcare delivery, Kumar & Clark's Medical Management and Therapeutics is portable, easy to access when you need it most, and full of cutting edge information and insights. "Snappy and concise, just what the junior doctor ordered!" - Dr Lyn D Ferguson, FY1 "Prescriptive and to the point" - Catherine Drouot, 3rd year medical student, Barts "An excellent text for both medical students and junior doctors alike." - Dr Lucy Blair, FY1 - Pocket-sized ward reference - Concentrates on the management and treatment of medical disorders - For junior doctors and senior medical students - Perfect complement to Kumar & Clark's Clinical Medicine and Ballinger's Essentials of Kumar & Clark's Clinical Medicine

The second edition of Neuroimmune Pharmacology bridges the disciplines of neuroscience, immunology and pharmacology from the molecular to clinical levels with particular thought made to engage new research directives and clinical modalities. Bringing together the foremost field authorities from around the world, Neuroimmune Pharmacology will serve as an invaluable resource for the basic and applied scientists of the current decade and beyond.

Sect. 1. Why women's health? -- Sect. 2. The role of women in health care and research -- Sect. 3. Reproductive health -- Sect. 4. Sexually transmitted diseases -- Sect. 5. International women's health -- Sect. 6. Women at work -- Sect. 7. Social determinants of health -- Sect. 8. Environmental exposures -- Sect. 9. Autoimmune disorders -- Sect. 10. Cardiovascular disease and cardiovascular risk in women -- Sect. 11. Cancer -- Sect. 12. Mental Disorders -- Sect. 13. Poorly understood conditions -- Sect. 14. AgingContributors. -- Preface. -- Women, Health, and Medicine: -- Why Women's Health? -- An Overview of Women and Health, M.B. Goldman & M.C. Hatch. -- Gender, Race and Class: From Epidemiologic Association to Etiologic Hypotheses, C.J. Rowland Hogue. -- The Role of Women in Health Care and Research: -- Section Editor: S.G. Haynes. -- Role of Advocacy Groups in Research on Women's Health, B. Seaman & S.F. Wood. -- State-of-the-Art Methods for Women's Health Research, S.G. Haynes & M ...