The management of and attitudes toward children and adults with Down syndrome have undergone considerable changes in the course of the condi tion's long history (Zellweger, 1977, 1981, Zellweger & Patil, 1987). J. E. D. Esquirol (1838) and E. Seguin (1846) were probably the first physicians to witness the condition without using currently accepted diagnostic designa tions. Seguin coined the terms furfuraceus or lowland cretinism in contradis tinction to the goiterous cretinism endemic at that time in the Swiss Alps. Esquirol, as well as Seguin, had a positive attitude toward persons who were mentally ill or mentally subnormal. Esquirol pioneered a more humane treatment in mental institutions and Seguin created the first homes in France, and later in the United States, aimed at educating persons who were mentally subnormal. The term mongolian idiocy was coined by J. H. L. Down in England (1866). The term is misleading in several respects: (1) Down identified the epicanthic folds seen in many children with Down syndrome with the additional skin fold in the upper lid occurring particularly in people of Oriental (Mongolian) descent; and (2) Down also erred by assuming that Down syndrome represented regression to an ethnic variant of lower cultural standing. Such an interpretation might have been understandable at a time when the myth of Anglo-Saxon superiority was widely accepted by the British. Charles Darwin's then highly acclaimed theory of origin of the species may have contributed to such a concept.

This standard work has been comprehensively revised and expanded to meet the needs of the modern practising and student dietitian. In tune with current trends, a greater emphasis has been placed on public health issues such as the treatment of childhood nutritional disorders in the community, including obesity and faltering growth. The book now also contains a dedicated chapter on the important issue of allergy prevention. Edited by leading experts at Great Ormond Street and the Institute of Child Health Officially supported by the British Dietetic Association Written for dietitians, by dietitians With worked examples of dietary management given throughout, Clinical Paediatric Dietetics is an indispensable guide for all those involved in the nutritional treatment of children.

This text provides speech and language therapists and language researchers with a state-of-the art review covering all aspects of speech and language development in individuals with Down syndrome. Written by leading experts in the field, it includes chapters on: the principles which should guide intervention; prelinguistic development; pragmatics and communication; literacy and language; augmentative communication; intervention with adolescents and adults; maintenance of skills for older adults; and a perspective on pertinent issues. Each chapter summarizes research and provides guidelines for effective interventions. This book should be a valuable guide to those working in the field who wish to be able to provide evidence-based interventions for individuals with Down syndrome and to contribute to their quality of life by improving their communication skills.

This book provides a concise yet comprehensive source of current information on Down syndrome. Research workers, scientists, medical graduates and paediatricians will find it an excellent source for reference and review. This book focuses on exciting areas of research on prenatal diagnosis - Down syndrome screening after assisted reproduction techniques, noninvasive techniques, genetic counselling and ethical issues. Whilst aimed primarily at research worker on Down syndrome, we hope that the appeal of this book will extend beyond the narrow confines of academic interest and be of interest to a wider audience, especially parents and relatives of Down syndrome patients.

Therapies and Rehabilitation in Down Syndrome covers the entire lifespan of a DS patient, from infancy to 60 years and beyond, focusing not simply on identifying problems, but providing a detailed look at major therapeutic approaches. Discussion includes future genetic therapy, questions of quality of life, hormone and other therapies for medical problems, prevention and treatment of normal and pathological aging, as well as psychomotoric rehabilitation. This is an important book not only for scientists concerned with various facets of DS, but practitioners looking for guidelines for therapies and clinical application of research findings.

First multi-year cumulation covers six years: 1965-70.