This issue of Emergency Medicine Clinics focuses on Clinical Toxicology and is edited by Drs. Daniel Lugassy and Silas Smith and includes such topics as Emerging Drugs of Abuse, Pediatric Toxicology; Dosing and Medical Errors and Child Abuse,The Approach to Toxin-Induced Coagulopathy,The Approach to Toxin-Induced Cardiovascular Failure, The Approach to Toxin-Induced Metabolic Acidosis, The Approach to Withdrawal Syndromes, The Approach to Radiation Exposure, and more.

In this issue of Emergency Medicine Clinics, guest editors Drs. Christopher P. Holstege and Joshua D. King bring their considerable expertise to the topic of Toxicology Emergencies. The field of medical toxicology has grown dramatically over the past decade, with the emergence of new pharmaceuticals, abused substances, chemicals within the workplace, and agents of terrorism. In this issue, top experts in the field address some of the more common, controversial, or emerging areas in this challenging area. - Contains 15 relevant, practice-oriented topics including the approach to the patient with an unknown overdose; emerging agents of substance abuse and misuse; differentiating the causes of metabolic acidosis in the poisoned patient; pediatric toxicology; and more. - Provides in-depth clinical reviews on toxicology emergencies, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Drs. Evie Marcolini and Haney Mallemat have assembled an expert panel of authors focusing on: Sepsis, Shock, Assessment and Treatment of the Trauma Patient in Shock, Coagulopathy and Hemorrhage, Vasopressors & Inotropes, Assessing Volume Status, Neurotrauma, Mechanical Circulatory Support, End of life, and more!

This issue of Emergency Medicine Clinics, guest edited by Mike Winters and Susan R. Wilcox, focuses on Emergency Department Resuscitation. This issue is one of four selected each year by series Consulting Editor, Dr. Amal Mattu. Topics include: Mindset of the Resuscitationist; Updates in Cardiac Arrest Resuscitation; Post-Arrest Interventions That Save Lives; Current Concepts and Controversies in Fluid Resuscitation; Emergency Transfusions; Updates in Sepsis Resuscitation; Pediatric Cardiac Arrest Resuscitation; The Crashing Toxicology Patient; The Crashing Obese Patient; Massive GI Hemorrhage; Updates in Traumatic Cardiac Arrest; Resuscitating the Crashing Pregnant Patient; Pearls & Pitfalls in the Crashing Geriatric Patient; Current Controversies in Caring for the Critically Ill PE Patient; and ECMO in the ED.

This issue of Emergency Medicine Clinics, edited by Drs. Stephen Borron and Ziad Kazzi focuses on emergencies arising from contact with Hazardous Materials. Article topics include: Selected classes and examples of dangerous industrial chemicals, weapons of mass destruction, and their syndromic identification; Hospital preparedness for chemical and radiological disasters; Personnel protection and decontamination of adults and children; Resources for toxicological information and assistance; Asphyxiants; Corrosives and irritants; Organophosphates and carbamates; Intentional and unintentional food, drug, and water contamination, and more!

This issue of Emergency Medicine Clinics edited by Drs. George Willis and Tyson Pillow focuses on Endocrine and Metabolic Emergencies and covers topics such as: Diabetes Mellitus, Hypothyroidism, Hyperthyroidism, Adrenal Emergencies, Derangements of Pottasium, Derangements of Sodium/Water Balance, Derangements of Calcium, Magnesium, and Phosphorus, Metabolic Acidosis, Neonatal Endocrine Emergencies and more.

This issue of Emergency Medicine Clinics edited by Drs. John Perkins and and Jonathan Davis focuses on emergencies related to Hematology/Oncology and covers topics such as: Oncologic Mechanical Emergencies, Neutropenic Fever, Oncologic Metabolic Emergencies, Acute Leukemias, Pediatric Oncologic Emergencies, Chemotherapeutic Medications and their Emergent Complications, Anemia, Thrombotic Microangiopathies (TTP, HUS, HELLP), Congenital Bleeding Disorders, Acquired Bleeding Disorders and Antithrombotic agents, Sickle Cell Disease, and more!

Toxicodynamics in Drug Research, Volume 2: Public Health and Toxicology Issues examines the implications of public health issues and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments on human health. Volume 2: Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics covers topics on pharmacokinetics and toxicokinetics such as population pharmacokinetics/toxicokinetics, the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. The book investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body. It discusses the mechanistic pathways of food toxicants and illustrates the molecular mechanisms of the chemopreventive role of dietary phytochemicals. It also delves into the toxic effects of medical treatments and materials. Ethical, legal, societal, and professional issues in toxicology round off the coverage providing a valuable resource to interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments. - Discusses the impact of pharmaceuticals, food, and chemical toxicants on human health - Examines the toxic effects of medical treatments, clinical administrations, and materials - Explores public health issues around drug safety and toxicology

This issue of Immunology and Allergy Clinics, edited by Dr. Pascal Demoly, is devoted to Drug Hypersensitivity. Articles in this issue include: Drug allergy diagnosis; Principles of drug allergy management: acute drug reactions, individual preventive measures, desensitization, general preventive measures; Antibiotics allergy; Non-steroidal anti-inflammatory drugs HS; Local and general anesthetics allergy; Radiocontrast media and dyes allergy; Chemotherapeutic agents allergy; Vaccine allergy; Biological agents HS; Anti-epileptic allergy; Iron and Vitamin Allergy; Antiviral drug allergy; Additive allergy; and Unmet needs in drug allergy.

As physicians, we have a constant passion for improving and maintaining patient's care and safety. The book is divided into three parts focusing on the essentials of general concepts, diagnosis, and management of accident and emergency medicine, as well as an academic approach to teaching in the emergency setting. The chapters selected for this book are written by an excellent group of recognized emergency surgeons and physicians from different countries and cultures facilitating a comprehensive and interesting approach to the problems of emergency treatment. We hope this book will be helpful and used worldwide by medical students, clinicians, and researchers enhancing their knowledge and advancing their objectives by a book that intends to become a reference text for research and practice within accident and emergency medicine.