The year 2019 has been prolific in terms of new evidence regarding the effects of coffee and caffeine consumption on diverse aspects of human functioning. This book collects 20 high-quality manuscripts published in Nutrients that include original investigation or systematic review studies of the effects of caffeine intake on human performance and health. The diversity of the articles published in this Special Issue highlights the extent of the effects of coffee and caffeine on human functioning, while underpinning the positive nature of most of these effects. This book will help with understanding why the natural sources of caffeine are so widely present in the nutrition behaviors of modern society.

The purpose of this Special Issue is to provide a thorough and up-to-date presentation of research investigating the impact of coffee and/or caffeine intake on various health outcomes. We welcome the submission of original research articles and/or systematic Reviews/meta-analyses focusing on several aspects of coffee/caffeine intake in relation to human health. Areas of interest include, but are not limited to, the following topics: - Human clinical trials of coffee or caffeine use in relation to disease or intermediate phenotypes. - Epidemiological studies of habitual coffee or caffeine intake in relation to human health, among the general public, as well as, among special populations (i.e., children, pregnant women, diabetics, cancer patients, hypertensives, etc.) - Mechanisms of action of nutrients and other bioactive components of coffee/caffeine. - Studies integrating genetic or physiological markers of coffee/caffeine intake to investigations of coffee and health.

Coffee in Health and Disease Prevention presents a comprehensive look at the compounds in coffee, their reported benefits (or toxicity risks) and also explores them on a health-condition specific level, providing researchers and academics with a single-volume resource to help in identifying potential treatment uses. No other book on the market considers all the varieties of coffee in one volume, or takes the disease-focused approach that will assist in directing further research and studies. The book embraces a holistic approach and effectively investigates coffee and its specific compounds from the biochemical to the nutritional well-being of geographical populations. This book represents essential reading for researchers in nutrition, dietetics, food science, biochemistry, and public health. - Presents one comprehensive, translational source for all aspects of how coffee plays a role in disease prevention and health - Experts in nutrition, diet, and food chemistry (from all areas of academic and medical research) take readers from the bench research (cellular and biochemical mechanisms of vitamins and nutrients) to new preventive and therapeutic approaches - Focuses on coffee composition; nutritional aspects of coffee; protective aspects of coffee-related compounds; specific coffee components and their effects on tissue and organ systems - Features sections on both the general effects of coffee consumption on the body as well as the effects of specific coffee compounds on specific organ systems

The role of green coffee bean (GCB) in human health is of emerging interest to the nutraceutical field, especially given its role in improving metabolic syndrome, including weight management, hypertension, diabetes, and neuroprotection. GCB extract contains a novel antioxidant known as chlorogenic acid (also caffeoylquinic acid), which has been shown to positively affect blood pressure, brain health, diabetes, and weight management. This book provides information on the diverse health benefits of green coffee bean extract, molecular mechanisms and signaling pathways, safety of GCB, dosage, and recommended usage. It focuses on the chemistry, biochemistry, pharmacology, and safety of GCB extract. GCB extract has brought a remarkable revolution in the nutraceutical marketplace. However, some controversies have been demonstrated recently. This book presents the state-of-the-art research studies from eminent scientists around the world on the potential and diversified health benefits of GCB extracts, with particular emphasis placed on the importance to standardize the appropriate extraction technology, quality control and assurance, and broad spectrum safety studies and human clinical studies to substantiate the regulatory claims and position the product in the marketplace.

The association between diet and health has been identified, and a healthy diet can help prevent various cardiovascular diseases (CVD). Dietary behaviors and dietary patterns are changing, especially in developing countries; with the ever-increasing amount of processed food and changing lifestyles, people eat more foods rich in energy, fat, free sugars, and salt, but not enough in fruits, vegetables, and other dietary fibers. CVD, including coronary heart disease, heart failure, stroke, and hypertension, are the leading cause of mortality worldwide. Poor dietary behaviors and patterns are risk factors for the continuing increase of CVD incidence, accounting for more than 11 million deaths.

The virtually universal popularity of caffeine, together with concerns about its potential pathogenic effects, have made it one of the most extensively studied drugs in history. However, despite the massive scientific literature on this important substance, most reviews have either focused on limited areas of study or been produced in popular form

This book is a printed edition of the Special Issue " Effects of Polyphenol-Rich Foods on Human Health" that was published in Nutrients

Heart Diseases: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Heart Diseases. The editors have built Heart Diseases: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heart Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Heart Diseases: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines. - Presents a completely revised and updated resource on the impact of nutraceuticals and various disease states such as diabetes and ophthalmic and dermal diseases - Grants an overview of the current state-of-the-science of nutraceuticals, their use and applications, and known adverse effects - Provides effective tools to evaluate the potential toxicity of any nutraceutical - Includes details of regulatory issues as written by international experts

Integrating scientific knowledge with today's most effective treatment options, Addiction Medicine: Science and Practice, 2nd Edition, provides a wealth of information on addictions to substances and behavioral addictions. It discusses the concrete research on how the brain and body are affected by addictions, improving your understanding of how patients develop addictions and how best to personalize treatment and improve outcomes. This essential text is ideal for anyone who deals with patients with addictions in clinical practice, including psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners. - Clearly explains the role of brain function in drug taking and other habit-forming behaviors, and shows how to apply this biobehavioral framework to the delivery of evidence-based treatment. - Provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding). - Discusses current behavioral and medical therapies in depth, while also addressing social contexts that may affect personalized treatment. - Contains new information on compliance-enhancing interventions, cognitive behavioral treatments, behavioral management, and other psychosocial interventions. - Includes neurobiological, molecular, and behavioral theories of addiction, and includes a section on epigenetics. - Contains up-to-date information throughout, including a new definition of status epilepticus, a current overview of Lennox Gastaut syndrome, and updates on new FDA-approved drugs for pediatric neurological disorders. - Features expanded sections on evidence-based treatment options including pharmacotherapy, pharmacogenetics, and potential vaccines. - Addresses addiction in regards to specific populations, including adolescents, geriatric, pregnant women, and health care professionals. - Includes contributions from expert international authors, making this a truly global reference to addiction medicine.