The limbic system (also known as the paleomammalian brain) is a collection of brain structures located in the middle of the brain. It is not a discrete system itself but rather a collection of structures—anatomically related but varying greatly in function. The limbic system is the centre for emotional responsiveness, motivation, memory formation and integration, olfaction, and the mechanisms to keep ourselves safe (Neuropsychotherapist.com). This book is a guide to surgical procedures for the limbic system. Beginning with an overview of brain embryology and anatomy, each of the following sections covers surgical approaches for disorders in different parts of the limbic system. Procedures are explained in a step by step approach, with emphasis on anatomical markers and avoidance of complications. The final chapters discuss brain mapping during surgery, giant and unusual tumours, and vascular lesions. Authored by a team of highly experienced, Illinois and Wisconsin-based neurosurgeons, the book is enhanced by anatomical dissections, operative photographs and illustrations, and includes a DVD ROM demonstrating surgical procedures. Key points Guide to surgical procedures for the limbic system Step by step approach with emphasis on anatomical markers and avoidance of complications Highly experienced, Illinois and Wisconsin-based author team Includes DVD ROM demonstrating surgical procedures

Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. - Provides information on the design and development of nanocarriers for targeting brain tumors - Outlines the working principles of different nanocarriers for targeting brain tumors - Includes case studies of different nanocarriers for targeting brain tumors

Neurosurgery is a rapidly developing and technically demanding branch of surgery that requires a detailed knowledge of the basic neuro-sciences and a thorough clinical approach. The Oxford Textbook of Neurological Surgery is an up-to-date, objective and readable text that covers the full scope of neurosurgical practice. It is part of the Oxford Textbooks in Surgery series, edited by Professor Sir Peter Morris. The book is split into 20 overarching sections (Principles of Neurosurgery, Neuro-oncology of Intrinsic Tumours; Extra-axial Tumours and Skull Lesions; Cerebro-Pontine Angle Tumours; Sellar and Supra-Sellar Tumours; Posterior Fossa Tumours; Pineal tumours; Uncommon Tumours and Tumour Syndromes; Neurotrauma and Intensive Care; Vascular Neurosurgery; Principles of Spinal Surgery; Spinal Pathology; Spinal Trauma; Peripheral Nerve Surgery; Functional Neurosurgery; Epilepsy; Paediatric Neurosurgery; Neurosurgery for Cerebrospinal Fluid Disorders and Neurosurgical Infection). Each section takes a dual approach with, 'Generic Surgical Management' chapters that focus on specific clinical problems facing the neurosurgeon (e.g. sellar/supra-sellar tumour, Intradural Spina Tumours etc.) and 'Pathology-Specific' chapters (e.g. Glioma, Meningeal Tumours, Scoliosis and Spinal Deformity, Aneurysm etc.). Where appropriate, this division provides the reader with easily accessible information for both clinical problems which present in a regional fashion and specific pathologies. The generic chapters cover aspects such as operative approaches, neuroanatomy and nuances. Specifically each chapter in the book incorporates several strands. Firstly the fundamental neuroscience (anatomy, pathology, genetics etc.) that underlies the clinical practice. Secondly, a review of the requisite clinical investigations (e.g. angiography, electrodiagnostics, radiology). Thirdly, a thorough evidence based review of clinical practice. Following this a consideration of the key debates and controversies in the field with 'pro-' and 'con-' sections (e.g. minimally invasive spine surgery, microsurgical treatment of aneurysms) is provided. A summary of the key papers and clinical scales relevant to neurosurgery form the concluding part. The book is a 'one-stop' text for trainees and consultants in neurosurgery, residents, those preparing for sub-specialty exams and other professionals allied to surgery who need to gain an understanding of the field. It acts as both a point of reference to provide a focussed refresher for the experienced neurosurgeon as well as a trusted training resource.

Comprehensive Human Physiology is a significantly important publication on physiology, presenting state-of-the-art knowledge about both the molecular mechanisms and the integrative regulation of body functions. This is the first time that such a broad range of perspectives on physiology have been combined to provide a unified overview of the field. This groundbreaking two-volume set reveals human physiology to be a highly dynamic science rooted in the ever-continuing process of learning more about life. Each chapter contains a wealth of original data, clear illustrations, and extensive references, making this a valuable and easy-to-use reference. This is the quintessential reference work in the fields of physiology and pathophysiology, essential reading for researchers, lecturers and advanced students.

This book covers stereotactic principles as well as functional stereotaxis, covering the history and uses of the techniques, treatments for specific conditions, and future developments. Includes a DVD demonstrating surgical procedures.

Textbook of Epilepsy Surgery covers all of the latest advances in the surgical management of epilepsy. The book provides a better understanding of epileptogenic mechanisms in etiologically different types of epilepsy and explains neuronavigation systems. It discusses new neuroimaging techniques, new surgical strategies, and more aggressive surgical approaches in cases with catastrophic epilepsies. The contributors also analyze the improved statistics of surgical outcome in different epilepsy types. This definitive textbook is an invaluable reference for neurologists, neurosurgeons, epilepsy specialists, and those interested in epilepsy and its surgical treatment.

This edited book explores the use of technology to enable us to visualise the life sciences in a more meaningful and engaging way. It will enable those interested in visualisation techniques to gain a better understanding of the applications that can be used in visualisation, imaging and analysis, education, engagement and training. The reader will also be able to learn about the use of visualisation techniques and technologies for the historical and forensic settings. The reader will be able to explore the utilisation of technologies from a number of fields to enable an engaging and meaningful visual representation of the biomedical sciences. The chapters presented in this volume cover such a diverse range of topics, with something for everyone. We present here chapters on technology enhanced learning in neuroanatomy; 3D printing and surgical planning; changes in higher education utilising technology, decolonising the curriculum and visual representations of the human body in education. We also showcase how not to use protective personal equipment inspired by the pandemic; anatomical and historical visualisation of obstetrics and gynaecology; 3D modelling of carpal bones and augmented reality for arachnid phobias for public engagement. In addition, we also present face modelling for surgical education in a multidisciplinary setting, military medical museum 3D digitising of historical pathology specimens and finally computational fluid dynamics.

Topic Editor Prof. Jorge Alvaro Gonzalez-Martinez has received a consulting grant from Zimmer Biomet. Prof. Stéphan Chabardès has also worked as a consultant for Zimmer Biomet. Prof. Chauvel has declared no competing interests with regards to the Research Topic subject.

If this were a traditional textbook of neuroanatomy, many pages would be devoted to a description of the ascending and descending pathways of the spinal cord and several chapters to the organization of the sensory and motor systems, and, perhaps, a detailed discussion of the neurological deficits that follow various types of damage to the nervous system would also be included. But in the first draft of this book, the spinal cord was mentioned only once (in a figure caption of Chapter 2) in order to illustrate the meaning of longitudinal and cross sections. Later, it was decided that even this cursory treatment of the spinal cord went beyond the scope of this text, and a carrot was substituted as the model. The organization of the sensory and motor systems and of the peripheral nervous system have received similar coverage. Thus, this is not a traditional text, and as a potential reader, you may be led to ask, "What's in this book for me?" This book is directed primarily toward those students of behavior who are either bored or frightened by the medically oriented texts that are replete with clinical signs, confusing terminology, and prolix descriptions of the human brain, an organ which is never actually seen in their laboratories. I should hasten to add, however, that this text may also serve some purpose for those who read and perhaps even enjoy the traditional texts.

This book fills the gap between the increasing demand for epilepsy surgical experience and limited training facilities in this area. It comprehensively describes surgical techniques, including tricks and pitfalls, based on the author’s 30 years of experience, providing optimal and effective training for young neurosurgeons by avoiding learning by trial and error. Moreover, it also includes useful information for epileptologists and other professionals involved in the epilepsy surgical program to allow them to gain a better understanding of possibilities and limitations of epilepsy surgery.