This volume includes papers originally presented at the 11th annual Computational Neuroscience Meeting (CNS 02) held in July 2002 at the Congress Plaza Hotel & Convention Center in Chicago, Illinois, USA. The CNS meetings bring together computational neuroscientists representing many different fields and backgrounds as well as many different experimental preparations and theoretical approaches. The papers published here range from pure experimental neurobiology, to neuro-ethology, mathematics, physics, and engineering. In all cases the research described is focused on understanding how nervous systems compute. The actual subjects of the research include a highly diverse number of preparations, modeling approaches and analysis techniques. Accordingly, this volume reflects the breadth and depth of current research in computational neuroscience taking place throughout the world.

The CNS meetings bring together computational neuroscientists representing many different fields and backgrounds as well as many different experimental preparations and theoretical approaches. The papers published here range from pure experimental neurobiology, to neuro-ethology, mathematics, physics, and engineering. In all cases the research described is focused on understanding how nervous systems compute. The actual subjects of the research include a highly diverse number of preparations, modeling approaches and analysis techniques. Accordingly, this volume reflects the breadth and depth of current research in computational neuroscience taking place throughout the world.

Computational neuroscience is a relatively new but rapidly expanding area of research which is becoming increasingly influential in shaping the way scientists think about the brain. Computational approaches have been applied at all levels of analysis, from detailed models of single-channel function, transmembrane currents, single-cell electrical activity, and neural signaling to broad theories of sensory perception, memory, and cognition. This book provides a snapshot of this exciting new field by bringing together chapters on a diversity of topics from some of its most important contributors. This includes chapters on neural coding in single cells, in small networks, and across the entire cerebral cortex, visual processing from the retina to object recognition, neural processing of auditory, vestibular, and electromagnetic stimuli, pattern generation, voluntary movement and posture, motor learning, decision-making and cognition, and algorithms for pattern recognition. Each chapter provides a bridge between a body of data on neural function and a mathematical approach used to interpret and explain that data. These contributions demonstrate how computational approaches have become an essential tool which is integral in many aspects of brain science, from the interpretation of data to the design of new experiments, and to the growth of our understanding of neural function.• Includes contributions by some of the most influential people in the field of computational neuroscience• Demonstrates how computational approaches are being used today to interpret experimental data• Covers a wide range of topics from single neurons, to neural systems, to abstract models of learning

Proceedings of the 2002 Neural Information Processing Systems Conference.

Attention is a central concept in psychology. The term 'attention' itself has persisted, even though it implies a static, insulated capacity that we use when it is necessary to focus upon some relevant or stimulating event. Riess Jones presents a different way of thinking about attention; one that describes it as a continuous activity that is based on energy fluctuating in time. A majority of attention research fails to examine influence of event time structure (i.e., a speech utterance) on listeners' moment-to-moment attending. General research ignores listeners endowed with innate, as well as acquired, temporal biases. Here, attending is portrayed as a dynamic interaction of an individual within his or her surroundings. Importantly, this interaction involves synchronicity between an attender and external events. This emphasis on time and synchronicity distinguishes the author's theory, called Dynamic Attending Theory (DAT), from other approaches to attending which characterize attention metaphorically as a filter, resource pool, spotlight, and so on. Recent research from neuroscience has lent support to Riess Jones' theory, and the goal of this book is to bring this new research as well as her own to the wide audience of psychologists interested in attention more broadly.

A comprehensive, integrated, and accessible textbook presenting core neuroscientific topics from a computational perspective, tracing a path from cells and circuits to behavior and cognition. This textbook presents a wide range of subjects in neuroscience from a computational perspective. It offers a comprehensive, integrated introduction to core topics, using computational tools to trace a path from neurons and circuits to behavior and cognition. Moreover, the chapters show how computational neuroscience—methods for modeling the causal interactions underlying neural systems—complements empirical research in advancing the understanding of brain and behavior. The chapters—all by leaders in the field, and carefully integrated by the editors—cover such subjects as action and motor control; neuroplasticity, neuromodulation, and reinforcement learning; vision; and language—the core of human cognition. The book can be used for advanced undergraduate or graduate level courses. It presents all necessary background in neuroscience beyond basic facts about neurons and synapses and general ideas about the structure and function of the human brain. Students should be familiar with differential equations and probability theory, and be able to pick up the basics of programming in MATLAB and/or Python. Slides, exercises, and other ancillary materials are freely available online, and many of the models described in the chapters are documented in the brain operation database, BODB (which is also described in a book chapter). Contributors Michael A. Arbib, Joseph Ayers, James Bednar, Andrej Bicanski, James J. Bonaiuto, Nicolas Brunel, Jean-Marie Cabelguen, Carmen Canavier, Angelo Cangelosi, Richard P. Cooper, Carlos R. Cortes, Nathaniel Daw, Paul Dean, Peter Ford Dominey, Pierre Enel, Jean-Marc Fellous, Stefano Fusi, Wulfram Gerstner, Frank Grasso, Jacqueline A. Griego, Ziad M. Hafed, Michael E. Hasselmo, Auke Ijspeert, Stephanie Jones, Daniel Kersten, Jeremie Knuesel, Owen Lewis, William W. Lytton, Tomaso Poggio, John Porrill, Tony J. Prescott, John Rinzel, Edmund Rolls, Jonathan Rubin, Nicolas Schweighofer, Mohamed A. Sherif, Malle A. Tagamets, Paul F. M. J. Verschure, Nathan Vierling-Claasen, Xiao-Jing Wang, Christopher Williams, Ransom Winder, Alan L. Yuille

For more than 30 years, the visual cortex has been the source of new theories and ideas about how the brain processes information. The visual cortex is easily accessible through a variety of recording and imagining techniques and allows mapping of high level behavior relatively directly to neural mechanisms. Understanding the computations in the visual cortex is therefore an important step toward a general theory of computational brain theory.

Epilepsy is a neurological disorder that affects millions of patients worldwide and arises from the concurrent action of multiple pathophysiological processes. The power of mathematical analysis and computational modeling is increasingly utilized in basic and clinical epilepsy research to better understand the relative importance of the multi-faceted, seizure-related changes taking place in the brain during an epileptic seizure. This groundbreaking book is designed to synthesize the current ideas and future directions of the emerging discipline of computational epilepsy research. Chapters address relevant basic questions (e.g., neuronal gain control) as well as long-standing, critically important clinical challenges (e.g., seizure prediction). Computational Neuroscience in Epilepsy should be of high interest to a wide range of readers, including undergraduate and graduate students, postdoctoral fellows and faculty working in the fields of basic or clinical neuroscience, epilepsy research, computational modeling and bioengineering. - Covers a wide range of topics from molecular to seizure predictions and brain implants to control seizures - Contributors are top experts at the forefront of computational epilepsy research - Chapter contents are highly relevant to both basic and clinical epilepsy researchers

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

This book presents the latest research in computational methods for modeling and simulating brain disorders. In particular, it shows how mathematical models can be used to study the relationship between a given disorder and the specific brain structure associated with that disorder. It also describes the emerging field of computational psychiatry, including the study of pathological behavior due to impaired functional connectivity, pathophysiological activity, and/or aberrant decision-making. Further, it discusses the data analysis techniques that will be required to analyze the increasing amount of data being generated about the brain. Lastly, the book offers some tips on the application of computational models in the field of quantitative systems pharmacology. Mainly written for computational scientists eager to discover new application fields for their model, this book also benefits neurologists and psychiatrists wanting to learn about new methods.