Lung transplantation is a successful therapeutic option for patients with end-stage respiratory failure. Although the clinical outcomes of this procedure have been constantly improving, yet the care of patients undergoing lung transplantation is still a striking challenge for the entire team involved in the process. The complexity of a clinical lung transplant program requires a trained, multi-specialist team and a continuing technical update. Technology provides exciting new opportunities for the improvement of clinical outcomes. This text provides a comprehensive, practical and up-to-date insight into clinical lung transplantation. It moves along the pre-, intra-, and post-operative phases of transplantation. It explores the most relevant surgical, medical and immunological concepts of this field. The contents focusses not only on the technical, scientific and medical aspects of lung transplantation, but also on the administrative, regulatory and nursing topics of running a lung transplant program. Rather than presenting purely theoretical chapters, the text sets the focus on clinical dilemmas and practical issues involving all the professionals who actively run a lung transplant program. The reader will be able to access the book for reference on any topic related to clinical care in lung transplantation. This text is intended as a practical resource for surgeons, physicians and health professionals involved in lung transplantation or in setting up a lung transplant program. All chapters are written by experts in their fields and will include the most up to date scientific and clinical information. The overall intent of this publication is to assist the health care provider in all the daily aspects of lung transplantation and to offer a modern, practical source of suggestions and answers.

This book details all aspects of lung transplantation and equips the general pulmonologist/physician with the necessary tools and knowledge to assist patients with the preparation for and care post lung transplantation. Written by global experts, chapters present general principles and history; indications and eligibility for lung transplantation, including screening for COPD, cystic fibrosis, scleroderma, Idiopathic pulmonary fibrosis (IPF) and idiopathic pulmonary arterial hypertension; approach to and complications of lung transplantation, such as prognostic markers, radiological approach, and immunology and rejection; and medical and surgical guidelines for lung transplantation. The goal of lung transplantation is to increase survival and to provide a greater quality of life for patients with untreatable end-stage lung disease and this book serves to best prepare clinicians in achieving that goal. Lung Transplantation: Evolving knowledge and New horizons offers valuable insights into this modality and is an authoritative resource for multidisciplinary services that include experts in pulmonary diseases, critical care, cardiology, thoracic surgery, infection diseases, internal medicine, radiology , immunology, nephrology, rehabilitation, psychology /psychiatry, nurses, social workers and nutritionists.

In this issue of Clinics in Chest Medicine, guest editors Drs. Luis Angel and Stephanie M. Levine bring their considerable expertise to the topic of Lung Transplantation. Top experts in the field cover key topics such as difficult decisions to transplant patients who are older, frail, underweight and obese; organ donation and variability in conversion to lung transplantation; conventional and novel approaches to immunosuppression; acute rejection and chronic allograft dysfunction; and more. - Contains 14 relevant, practice-oriented topics including COVID-19 and lung transplantation; the lung transplant candidate: indications, timing and selection criteria; bilateral lung transplantation vs. single lung transplant: complications, quality of life, and survival; critical care management of the lung transplant recipient; and more. - Provides in-depth clinical reviews on lung transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease Comprehensive textbook covering all aspects of the care of patients with advanced heart or lung disease Transplantation and Mechanical Support for End-Stage Heart and Lung Disease is the most comprehensive and contemporary textbook available that addresses the medical and surgical treatment options for patients with end-stage heart and lung disease. All facets of these complex and resource-intensive therapies are covered by leading experts — including the basics of transplant immunology, databases, regulatory and ethical aspects of transplantation and conventional and new modalities of donor organ harvest. Transplantation and Mechanical Support for End-Stage Heart and Lung Disease includes further information on topics such as: Historical developments that facilitated heart and lung transplantation; engineering advances in continuous flow technologies Transplant organizations, oversight, structure, process, databases and registries in the thoracic transplants and MCS field Current strategies in immune modulation, desensitization protocols and mechanisms of allograft rejection and tolerance/immunosenescence Detailed descriptions of donor and recipient surgical procedures as well as comprehensive implantation techniques for all available short- and long-term mechanical circulatory support devices, including ECMO Organ allocation and prioritization, donor evaluation, high risk donors, marginal donors, and risk assessment Richly enhanced with summary tables and color illustrations to provide an engaging and supportive learning experience, the book will serve as a highly valuable source of contemporary knowledge for medical students, residents, nurses, perfusionists, physicians and surgeons involved in the care of these desperately ill group of patients. “This comprehensive book covers all aspects of advanced heart and lung failure treatment, including shock, short-term and durable mechanical assistance, as well as transplantation. The in-depth information will be welcome by newcomers in the field as well as seasoned veterans.” —Andreas Zuckermann, M.D Vice-Chair, Department of Cardiac Surgery, Director of Cardiac Transplantation Program, Medical University of Vienna, Vienna General Hospital “This comprehensive tour-de-force compendium covers practical issues of clinical administration, program development, care pathways, ongoing challenges and opportunities in each treatment area as a must go-to reference for guidance in the rapidly evolving fields of mechanical circulatory support and transplantation.” —Mandeep R. Mehra, MBBS, MSc, FRCP Executive Director, Center for Advanced Heart Disease, Brigham and Women’s Hospital, Harvard Medical School “This unique textbook authored by key opinion leaders is a refreshing ???wind of change??? in our field, one that will well serve all professionals involved in the care of end-stage heart and lung patients for many years to come.” —Marcelo Cypel MD, MSc, FACS, FRCSC Surgical Director Ajmera Transplant Centre at UHN , University of Toronto

Diffuse parenchymal lung disease (DPLD) represents a large and heterogeneous group of disorders. Although new insights into the pathogenesis and new techniques such as high-resolution-CT have led to a better understanding of DPLD, clinical management remains a challenge. This volume is designed to become a valuable aid in the diagnosis and management of DPLD. It starts with general topics such as a new classification system for DPLD, the general diagnostic approach, and clinical evaluation of the patient by radiology, histological patterns and bronchoalveolar lavage. This is followed by consideration of some basic aspects such as the genetics of DPLD, the principles of granuloma formation, pulmonary fibrogenesis and vasculitis, as well as novel treatment approaches. A large part of the book consists of disease-specific chapters, which discuss granulomatous disorders, idiopathic pulmonary fibrosis and other entities of idiopathic interstitial pneumonia, the collagen vascular diseases, drug-induced infiltrative lung disease as well as orphan diffuse lung diseases including Langerhans' cell histiocytosis, lymphangioleiomyomatosis and pulmonary alveolar proteinosis. Special chapters on DPLD in children and lung transplantation for end-stage fibrosis complete this comprehensive publication. Written by internationally known experts, this well-organized volume is recommended to a wide audience including respiratory physicians in training, practice and research as well as radiologists and pulmonary pathologists.

In consultation with Consulting Editor, Dr. Jan Foster, Dr. Brian Boling has put together a state-of the-art issue of the Critical Care Nursing Clinics devoted to Cardiothoracic Surgical Critical Care. Clinical review articles are specifically devoted to the following: Fast Track Cardiac Surgery; Options for Minimally Invasive Valvular Surgery; Surgical Interventions for the Treatment of Advanced Heart Failure; Lung Transplantation; Surgical Treatment of Lung Cancer; Post-Operative Management of Tetralogy of Fallot; Advanced Hemodynamic Monitoring in Cardiothoracic Surgery; Vasoactive Infusions in Cardiothoracic Surgery; Common Post Cardiothoracic Surgery Arrhythmias; Pain Control in the Cardiothoracic Surgery Patient; Renal Complications of Cardiothoracic Surgery; The Role of ECMO in Post Cardiotomy Shock; Resuscitation of Patients Who Arrest After Cardiac Surgery; and End of Life Care in Cardiothoracic Surgery. Readers will come away with the latest information they need to improve improves of cardiothoracic surgical patients.

Lung Transplantation: Principles and Practice covers the current practice in donor and recipient management as well as current treatment strategies and outcomes. With 39 chapters from international experts in the field, this book covers the current practice in donor and recipient management as well as current treatment strategies and outcomes. It discusses significant advances achieved in the past decade in areas such as donor allocation, organ preservation and management, recipient selection, management and support, surgical and critical care techniques, immune suppression, and infection prophylaxis. Specific instances of pulmonary disease that commonly necessitate lung transplantation are also covered.

In this issue of Thoracic Surgery Clinics, guest editors Drs. Jasleen Kukreja and Aida Venado bring their considerable expertise to the topic of Lung Transplantation. Top experts in the field cover key topics such as inpatient management of the acutely decompensating lung transplant candidate, lung allograft rejection, management of the potential lung donor, postoperative management of lung transplant recipients, and more. - Contains a variety of relevant, practice-oriented topics including donation after circulatory death; lung transplant for ARDS; centralized organ recovery and reconditioning centers; infectious complications in lung transplantation; anesthetic management during lung transplantation; and more. - Provides in-depth clinical reviews on lung transplantation, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Critical care medicine is responsible for many of the most important advances in outcomes after cardiothoracic surgery in the past two decades. The expertise developed in this subspecialty accounts for the resiliency that characterizes gold standard results evident in institutions recognized for excellence. This volume is intended to share ideas and algorithms that will improve outcomes in cardiothoracic critical care units. This book is part of the Difficult Decisions in Surgery series that covers surgical specialties. The volumes are multi-authored, containing brief chapters, each of which are devoted to one or two specific questions or decisions within that specialty that are difficult or controversial. The volumes are intended as a current and timely reference source for practicing surgeons, surgeons in training, and educators that describe the recommended ideal approach, rather than customary care, in selected clinical situations.