Several studies have argued that there is a correlation between short stature and negative experiences and characteristics, such as social discrimination, economic disadvantage, health problems (especially for men). The idea that short men have a disadvantage in social interactions and in partner choices is also widespread in popular culture and common knowledge. It is now possible to use recombinant human growth hormone (hGH) to treat children with idiopathic short stature (ISS), namely children who are shorter than average for unknown medical reasons. Critics argue that there is a lack of evidence of both psychological distress caused by short stature and the efficacy of the treatment in increasing children’s well-being. This controversy is reflected in international drug evaluations: while the Food and Drug Administration (FDA) in the US granted marketing authorisation for hGH for children with ISS in 2003, the European Medicines Agency (EMA) refused it in 2007. The research presented here had two aims: first, to identify and analyse the norms, values and assumptions about short stature and the use of hGH treatment for children with ISS, found within sociocultural, philosophical and regulatory discussions of these, and within narrated lived experiences of short stature. Second, to critically and reflectively discuss how these analyses contribute to bioethical debates on the use of hGH treatment for children with ISS. It employs what it calls a critical paediatric bioethics theoretical approach, which deems as important to carefully analyse different reasoning, conceptualisations and arguments around the object of study, through a self-reflective analysis that is also sceptical about other forms of problematisation, and that combines philosophical analyses while being open to social implications and drawing upon empirical methods. The first article proposes a critical understanding of medicalisation as both a concept and a phenomenon, and explores what insights such critical understanding brings to ethical discussions about hGH for ISS. It argues that three main ethical issues concern the medicalisation of short stature: the downplayed role of the qualitative dimension of short stature, the justification of the treatment (as sometimes based on uncritically assumed social beliefs and unrealistic parental expectations), and possible misconduct of stakeholders. The second article examines the arguments for and against granting marketing authorisation of hGH treatment for the indication of ISS presented in selected FDA and EMA documents. It combines argumentative analysis with an approach to policy analysis called ‘what’s the problem represented to be’ and focuses on underlying assumptions and presuppositions about short stature and hGH treatment for ISS. It then discusses these arguments through the relational, experiential and cultural understandings of disability, and argues that the choice about whether to give hGH is not merely a choice based on efficacy and safety, but requires an examination of the values that we transmit by that choice. The third article examines how and why attendance to lived experiences of height is needed in bioethical and biomedical discussions of hGH treatment for children with ISS. It first describes what it defines as the ‘problem-oriented’ approach to the debate about hGH treatment for children with ISS. It then offers a sociophenomenological analysis of whether and, if so, when and how, height matters to the interviewed people in the Netherlands who are shorter than average without any known medical reasons. The sociophenomenological analysis shows the richness of meanings of lived experiences of short stature that cannot be captured by the problem-oriented approach, and suggests complementing clinical practices with narrative approaches. This research contributes to the ethical debate about using hGH for children with ISS, setting a critical gaze onto the social perception of short stature, highlighting some ethical challenges met by stakeholders involved at different levels (such as families, medical professionals and policy makers), and providing new insights into how to address these ethical issues. It is, therefore, of interest to stakeholders, bioethicists and lay people willing to explore alternative ways to address such bioethical dilemmas, and other paediatric interventions that aim to normalise children’s bodily characteristics.

This volume provides a practical overview of the ethical issues arising in pediatric practice. The case-based approach grounds the bioethical concepts in real-life situations, covering a broad range of important and controversial topics, including informed consent, confidentiality, truthfulness and fidelity, ethical issues relating to perinatology and neonatology, end-of-life issues, new technologies, and problems of justice and public health in pediatrics. A dedicated section also addresses the topics of professionalism, including boundary issues, conflicts of interests and relationships with industry, ethical issues arising during training, and dealing with the impaired or unethical colleague. Each chapter contains a summary of the key issues covered and recommendations for approaching similar situations in other contexts. Clinical Ethics in Pediatrics: A Case-Based Textbook is an essential resource for all physicians who care for children, as well as medical educators, residents and scholars in clinical bioethics.

Linear growth is a biological process of fundamental importance to the physical and psychological make-up of a child and adolescent but which can be subject to a number of interruptions and disorders. The management and treatment of patients with growth disorders constitues a major, and important, part of practice in clinical paediatrics, while in

The explosion of knowledge in the area of pharmaceutical biotechnology can certainly justify the need for a second edition of this text. While new techniques and topics have been introduced to ensure the content is current, the format of Pharmaceutical Biotechnology, 2nd Edition has remained essentially unchanged. It provides a clear, concise self-teaching guide to the essentials of pharmaceutical biotechnology. Key topics are covered systematically, with self-tests at the end of each chapter, helping the reader acquire a basic fund of knowledge in this important area of pharmacology. While prepared for undergraduate pharmacy students, this self-teaching text also serves the professional needs of all those in drug research, development, administration and government regulation.

A Doody's Core Title for 2023! The most practical, up-to-date guide available for accurately diagnosing and effectively treating child patients—from birth to adolescence The authoritative resource to pediatric medical conditions most often encountered in daily practice, CURRENT Diagnosis and Treatment Pediatrics provides the evidence-based information readers need to deliver effective care in every situation. Packed with 200 photos and illustrations, this evidence-based text offers succinct, accurate overviews of important pediatric health concerns, such as childhood nutrition and eating disorders; substance use; psychiatric disorders; child abuse; oral medicine and dentistry; immunization; and emergencies and injuries. Complete with an invaluable guide to normal laboratory values, it provides detailed descriptions of diseases, as well as diagnostic and therapeutic procedures, and present all information in the time-saving style that makes LANGE CURRENT books so popular: Problem, Essentials of Diagnosis, Clinical Findings, Differential Diagnosis, Treatment, and Prognosis. NEW to this edition:

The benchmark evidence-based pharmacotherapy text-now in full color! Additional chapters are available online When it comes to helping you develop a mastery of evidence-based medicine for optimal patient outcomes, no book can match Pharmacotherapy: A Pathophysiologic Approach. Like the discipline it covers, the scope of this trusted resource goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. The book also delves into psychosocial issues that affect compliance ... topics related to a patient's ability to understand and manage often-complex therapy... and lifestyle changes that may reduce the need for drug therapy or improve pharmacotherapeutic outcomes. Pharmacotherapy delivers everything you need to provide safe, efficacious drug therapy across the full range of therapeutic categories. FEATURES NEW! Expanded evidence-based recommendations NEW! Extended coverage of the timely issue of palliative care and pain medicine NEW! Important chapters on Pulmonary Hypertension, Disorders of Calcium and Phosphorus Homeostasis, and Multiple Myeloma, Outstanding pedagogy, including: “Key Concepts” highlighted in each chapter “Clinical Presentation” boxes summarize the most common disease signs and symptoms covered in each chapter “Clinical Controversies” boxes-presented in the Treatment sections of the disease-oriented chapters-examine the complicated issues faced by students and clinicians in providing drug therapy Clear therapeutic recommendations in each disease-specific chapter “Evaluation of Therapeutic Outcomes” boxes in each disease-specific chapter, containing key monitoring guidelines that facilitate the development of a pharmaceutical, nursing, or medical care plan

Speaking for the Dead is an incisive examination of the highly topical and often controversial issues surrounding the use of human cadavers in scientific research. Fully revised and updated to include recent developments in this area, this new edition incorporates the repeated organ scandals in the UK, body parts scandals in the United States, and the abuses of bodies in China. The book provides new material on neuroimaging, neuroethics and Alzheimer's disease and the major ethical issues they raise for society, in addition to discussing plastination in the form of BodyWorlds types of exhibitions. As human anatomists and bioethicists, the authors offer a unique perspective on these issues, crossing the boundaries between clinical, medical, legal and ethical concerns. Their exploration of both historical and contemporary data results in a clear and comprehensive examination of issues at the forefront of bioethics. With its clear writing style and use of non-technical language Speaking for the Dead will be an essential book for all those interested in bioethics, an area which continues to increase in significance with the development of new techniques for the manipulation of human cadavers. As human anatomists and bioethicists, the authors offer a unique perspective on these issues, crossing the boundaries between clinical, medical, legal and ethical concerns. Their exploration of historical developments as well as their analyses of recent case studies result in a pertinent and comprehensive examination of issues at the forefront of bioethics.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. An Engagingly Written, Case-Based Review for the Pediatrics Board Exam McGraw-Hill Specialty Board Review: Pediatrics is the perfect resource to help you prepare for the American Board of Pediatrics (ABP) certification or recertification examination. Written in a refreshing conversational tone, this unique review utilizes a case-based presentation that includes questions, answers, and discussion. Numerous tables, figures, and photographs encapsulate important information and make it easier for readers to study and remember. The content is weighted to match the board exam – so you can focus on what you really need to know for the highest score possible. · The 35 chapters in the book correspond to the 35 sections of the ABP content specifications · Each chapter is written by specialists in the topic · Comprehensive final exam appears at the end of the book · Great as clinical refresher · Each question is referenced to chapter content for more in-depth study