Enter the world of the little-known and even less understood heroes of police work in Las Vegas -- the forensic investigators. Led by veteran Gil Grisson, the remarkable team assigned to the Criminalistics Bureau's graveyard shift must combine cutting-edge scientific methods with old-fashioned detective savvy as they work to untangle the evidence behind the yellow police tape. Far from the glittering lights and 24/7 spectacle of the Strip, the Las Vegas Crime Lab's team of investigators is gearing up for a rough night ahead. A brutal shooting at a cheap motel may be business as usual for CSIs Catherine Willows and Nick Stokes, but as they process the crime scene and quickly identify the victim as a noted local private investigator, nothing could prepare them for the shock of finding physical evidence belonging to none other than their own respected colleague Detective Jim Brass. Meanwhile, CSIs Greg Sanders and Riley Adams are called to a nearby airport where they must face the ultimate locked room mystery: how a pilot flying solo in a small private plane wound up murdered while miles above the ground…

It’s a hot, early autumn evening in the small resort town of Mount Charleston, NV, where six firefighters are battling a massive blaze that threatens expensive homes . . . a blaze that will cost them their lives. Initially, the police determine that the fire was human-started, and the state wants to prosecute to the fullest extent of the law with six counts of homicide. Now the team of Sin City’s finest criminologists, led by Catherine Willows, are assigned to work a crime scene far from the glittering lights and 24/7 spectacle of the Las Vegas Strip, and soon find much more than they bargained for. . . . Meanwhile, Ray Langston and Nick Stokes are called to a crime scene where a dog has taken a key piece of evidence—a severed human hand—under a suburban home’s crawl space. What’s even more disturbing is that it’s not the first severed hand that’s turned up lately—there have been four other incidents around Las Vegas over the past twelve months. . . .

Aruthless and expertly trained contract killer is on assignment in Nevada's remote Desert National Wildlife Range... and he deliberately sets in motion a series of seemingly unconnected events that will test the skills of Gill Grissom and his team of CSIs -- Catherine Willows, Nick Strokes, Warrick Brown, Sara Sidle, and Greg Sanders -- to their limits. For all is not as it appears in this federal refuge, as law enforcement and lawbreakers alike are quickly caught up in a growing crime scene that leads to a deadly game of one-upmanship.

'Nevada Rose' Deville was one of the most beautiful and desired sports groupies in Las Vegas, a fixture at the trendiest casinos and clubs on the Strip. But the endless party comes to an end the morning her nude body is found bound and gagged in her home. As crime scene investigators Catherine Willows and Warrick Brown dig deeper, all the evidence points to Mark Baker, aka 'The Fireball' -- a hard-throwing major-league baseball pitcher and collector of gorgeous women who recently conducted a very public affair with the deceased. Meanwhile, miles away on the grounds of a world-class championship golf course, Gil Grissom is probing the macabre discovery of a John Doe -- an intense investigation which will unearth a web of jealousy and distrust, fuelled by a bitter sibling rivalry over a 'Nevada Rose' of a very different nature...

Far from the glittering lights and 24/7 spectacle of the Strip, the Las Vegas Crime Lab's team of investigators is gearing up for a rough night ahead.... A brutal shooting at a cheap motel may be business as usual for CSIs Catherine Willows and Nick Stokes, but as they process the crime scene and quickly identify the victim as a noted local private investigator, nothing could prepare them for the shock of finding physical evidence belonging to none other than Detective Jim Brass.... Meanwhile, CSIs Greg Sanders and Riley Adams are called to a nearby airport where they must face the ultimate locked room mystery: how a pilot flying solo in a small private plane wound up murdered while miles above the ground....

United States and Canada.

The machinations of a new supervisor may have altered Gil Grissom's team of skillful CSIs, as Catherine Willows, Nick Stokes, and Warrick Brown are reassigned from the graveyard shift to the swing shift. That doesn't mean, however, that their paths will never cross. During the course of their separate investigations, the teams must unite again to investigate two distinct murders -- atrocities that are oddly aligned as they share much of the same collective evidence. Despite the different M.O.s, the CSIs are uncovering two wildly imperfect crimes that could possibly add up to an almost perfect one...