Pathology of lung cancers is presented, along with targeted therapies current in 2010. Additionally, asbestosis, mesothelioma, and malignant lymphomas are presented with reference to their features, differential diagnoses, and prognosis. Topics include: Bronchioloalveolar carcinoma and minimally invasive adenocarcinoma; Neuroendocrine tumors; Lung carcinoma staging problems; Targeted therapies in lung cancer; Benign and malignant mesothelial proliferations; Asbestos related lung disease; Primary Lymphoproliferative diseases of the lung; Vasculitis; and Small airway disease.

Using a concise, understandable approach, Principles of Pulmonary Medicine, 8th Edition, provides a broad overview of this fast-changing field, integrating clinical topics with underlying physiologic, pathophysiologic, and basic science concepts. From cover to cover, it clearly explains and illustrates even the most challenging concepts in a uniquely readable and digestible fashion. With its emphasis on pathophysiology and diagnosis as the basis for optimal management of respiratory disorders, this popular text is an essential reference for medical students, trainees, and those looking for a practical update on both acute and chronic pulmonary diseases. Presents physiologic concepts, pathogenetic and pathophysiologic mechanisms, and radiologic and pathologic correlates of disease in a clear, understandable manner. Features extensive content updates on interstitial lung disease, emerging and/or viral infections (including COVID-19), lung cancer, asthma, and new biologic and immunologic treatments available for a variety of diseases. Contains excellent visuals for understanding and interpreting pulmonary disease with easy-to-understand anatomic illustrations and accompanying radiologic and pathophysiologic images—now all in full color for the first time. This edition provides even more images, especially chest radiographs and CT scans, that offer more examples of clinical disorders. Provides therapeutic strategies, including evidence for assessing relative benefits, harms, and costs. Includes useful appendices that provide simplified methods for interpreting pulmonary function tests and arterial blood gases, while also presenting sample problems that test the reader’s ability to use respiratory equations, assess pulmonary function abnormalities, and interpret arterial blood gases. Provides access to extensive online content such as author commentaries, video clips, audio recordings of lung sounds, and over 200 case-based self-assessment questions modeled after the USMLE exam. Includes margin notes throughout the text that summarize the major points and concepts and allow the reader to quickly review the material.

In this issue of Surgical Pathology Clinics, guest editor Dr. Alain Borczuk brings his considerable expertise to the topic of New Frontiers in Thoracic Pathology. Top experts provide new insights into emerging technology that will affect thoracic pathology in both neoplastic and non-neoplastic disease. This issue covers updates in the utilization of molecular testing in surgical pathology of lung cancer and mesothelioma, highlights uncommon tumors in the differential of common tumors, and shares new approaches to non-neoplastic disease, including new clinicopathologic entities. - Contains 13 relevant, practice-oriented topics including silicosis and non-asbestos associated pneumoconiosis; pathology of COVID-19 lung disease; salivary gland type lung cancer; microsatellite instability, mismatch repair and tumor mutation burden in lung cancer; artificial intelligence in lung pathology; and more. - Provides in-depth clinical reviews on new frontiers in thoracic pathology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic. Contains 15 practice-oriented topics including new entities and challenges in pediatric hematopathology; IgG4-related lymphadenopathy and lymphoproliferative disorders; the changing landscape of follicular lymphoma: new variants and related entities; breast implant-associated lymphomas; controversies in splenic histiocytic, dendritic, and stromal cell lesions; and more. Provides in-depth clinical reviews on hematopathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity. Compare your findings to more than 3,300 outstanding illustrations that capture the characteristic presentation of every type of lesion. Avoid diagnostic pitfalls using Dr. Rosai's expert observations on what to look for, what to be careful about, and which presentations can be misleading. Find quick answers on tumor staging, quality control procedures, and the handling of gross specimens through valuable appendices. Make optimal use of all the very latest advances including our increased understanding of the genetic basis of inherited and acquired disease, the newest molecular genetic and immunohistochemical techniques, and the most recent WHO disease classification schemes.

This issue of Surgical Pathology Clinics, guest edited by Dr. Jessica Davis, is devoted to Challenges & Updates in Pediatric Pathology. Articles in this issue include: Advances and Pitfalls in the Diagnosis of Hirschsprungs Disease, Updates in Pediatric Enteropathies: Differential Diagnosis, Testing, and Genetics, Pediatric Liver Tumors: Updates in Classification, New Prognostic Indicators in Pediatric Adrenal Tumors: Neuroblastoma & Adrenal Cortical Tumors, Pediatric Cystic Lung Lesions, Strategies for the Neonatal Lung Biopsy: Histology to Genetics, Wilm’s Tumor: Challenges and Newcomers in Prognosis, Pediatric Renal Tumors: Updates in the Molecular Era, Newcomers in Vascular Anomalies, Spindle Cell Rhabdomyosarcoma: Further Subcategorization, Pediatric & Infantile Fibroblastic/myofibroblastic Tumors in the Molecular Era, Round Cell Sarcomas: Newcomers and Diagnostic Approaches, CNS Embryonal Tumors: Testing Strategies for Integrated Diagnosis, Updates in Pediatric Gliomas, and more.

In this issue of Surgical Pathology Clinics, guest editor Dr. Christopher J. VandenBussche brings his considerable expertise to the topic of The Current and Future Impact of Cytopathology on Patient Care. Top experts discuss how minimally invasive procedures can provide critical information to guide patient management--for example, cytopathology specimens that allow for the timely and personalized treatment of patients, reducing the number of more costly and invasive procedures. This issue focuses on the recognition of critical cytomorphologic features, current and developing options for ancillary testing, and the potential use of cytopathology specimens in precision medicine (precision cytopathology). Contains 12 relevant, practice-oriented topics including cervical HPV testing: current and future impact on patient care; lymph node fine needle aspiration: current and future impact on patient care; machine learning in cytopathology; and more. Provides in-depth clinical reviews on the current and future impact of cytopathology on patient care, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic. Contains 13 relevant, practice-oriented topics including PSC, small duct PSC, IgG4 and ischemic cholangiopathy: what do you see on needle biopsy?; evolving understanding of noncirrhotic portal hypertension; practical guide, challenges, and pitfalls in liver fibrosis staging; liver pathology after hematopoietic stem cell transplant; medical Liver injury related to cancer treatment; and more. Provides in-depth clinical reviews on liver pathology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

First multi-year cumulation covers six years: 1965-70.