This is a nearly complete collection of Chapters that provide an up to date overview of all aspects of Head and Neck cancer. It is written by professionals but is not only intended for other professionals, but students, patients, policy makers, etc. There are so many aspects to this group of diseases that even the most seasoned professional will learn something from having read this book.

Prof. Wagner owns stock shares in Pfizer and Merck, patent pending on whole organ decellularisation and recelluarisation US20160067378A1. The other Topic Editors declare no competing interests with regards to the Research Topic theme.

Explores recent research and innovations in the field of endodontics and provides evidence-based guidelines for contemporary dental practice Endodontic Advances and Evidence-Based Clinical Guidelines provides a comprehensive and up-to-date description of recent research findings and their impact on clinical practice. Using an innovative approach to the field, the book enables readers to translate the current body of knowledge on endodontic diseases and treatment into guidelines for enhancing patient care. Divided into four parts, the book first addresses new research findings and advances in technology, techniques, materials, and clinical management. In addition, it provides revised clinical guidelines for a variety of areas within the specialty, such as endodontic diagnosis, treatment planning, management of endodontic emergencies, regenerative endodontic procedures, three-dimensional imaging, and the use of systemic antibiotics. Each chapter contains numerous high-quality illustrations and clinical cases highlighting current research directions, key concepts, and new trends in clinical techniques and education. Endodontic Advances and Evidence-Based Clinical Guidelines: Presents the latest understanding of current literature, evidence, and clinical practice Examines new trends, treatments, and advanced diagnostic techniques in the field Covers a wide range of topics, including management of root canals, repair of perforation defects, removal of root filling materials, and alternatives to root canal treatment Endodontic Advances and Evidence-Based Clinical Guidelines is an invaluable resource for undergraduate and postgraduate dental students, general dental practitioners, endodontic specialists, researchers in the field of endodontics, and clinicians, researchers, and educators in other fields of dentistry.

Advances in Blood Transfusion Research and Application / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Blood Transfusion. The editors have built Advances in Blood Transfusion Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Blood Transfusion in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Blood Transfusion Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

With a history that likely dates back to the dawn of human civilization more than 10,000 years ago, and a record that includes the domestication and selective breeding of plants and animals, the harnessing of fermentation process for bread, cheese, and brewage production, and the development of vaccines against infectious diseases, biotechnology has acquired a molecular focus during the 20th century, particularly following the resolution of DNA double helix in 1953, and the publication of DNA cloning protocol in 1973, and transformed our concepts and practices in disease diagnosis, treatment and prevention, pharmaceutical and industrial manufacturing, animal and plant industry, and food processing. While molecular biotechnology offers unlimited opportunities for improving human health and well-being, animal welfare, agricultural innovation and environmental conservation, a dearth of high quality books that have the clarity of laboratory manuals without distractive procedural details and the thoroughness of well-conversed textbooks appears to dampen the enthusiasm of aspiring students. In attempt to fill this glaring gap, Handbook of Molecular Biotechnology includes four sections, with the first three presenting in-depth coverage on DNA, RNA and protein technologies, and the fourth highlighting their utility in biotechnology. Recognizing the importance of logical reasoning and experimental verification over direct observation and simple description in biotechnological research and development, the Introduction provides pertinent discussions on key strategies (i.e., be first, be better, and be different), effective thinking (lateral, parallel, causal, reverse, and random), and experimental execution, which have proven invaluable in helping advance research projects, evaluate and prepare research reports, and enhance other scientific endeavors. Key features Presents state-of-the-art reviews on DNA, RNA and protein technologies and their biotechnological applications Discusses key strategies, effective thinking, and experimental execution for scientific research and development Fills the gap left by detailed-ridden laboratory manuals and insight-lacking standard textbooks Includes expert contributions from international scientists at the forefront of molecular biotechnology research and development Written by international scientists at the forefront of molecular biotechnology research and development, chapters in this volume cover the histories, principles, and applications of individual techniques/technologies, and constitute stand-alone, yet interlinked lectures that strive to educate as well as to entertain. Besides providing an informative textbook for tertiary students in molecular biotechnology and related fields, this volume serves as an indispensable roadmap for novice scientists in their efforts to acquire innovative skills and establish solid track records in molecular biotechnology, and offers a contemporary reference for scholars, educators, and policymakers wishing to keep in touch with recent developments in molecular biotechnology.

The Human Genome Project was sold to the general public largely on the basis that a complete picture of the structure of human DNA would lead to new and better medicines. These medicines would be better because they would be tailored to individual patients, maximising the chances of a therapeutic response and mi nimising the risks of an adverse event. Taking the idea further, pundits have pre dicted that the time will come when we could carry our DNA on a card which could be read rapidly and enable the physician to choose the best drug. This is the future. This is pharmacogenetics. When the draft human DNA sequence was announced and scientists were as ked how this would help drug development, the example most frequently given was the debrisoquine model - where poor metabolisers of this hypotensive agent are exposed to higher plasma levels from a standard dose and at risk of collapse from excessive hypotension. This observation was made over 20 years ago and predated designs to sequence the human genome. Nonetheless, it raised aware ness of variation in drug metabolism and was correctly assigned to genetic poly morphisms affecting CYP2D6. Together with the discovery of pseudocholinestera se deficiency, it marked the birth of pharmacogenetics. The debrisoquine example is an interesting one and worthy of further analysis.

Meticulously reviewed and updated for today's medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases—all designed to help students master this complex topic in the most efficient, effective manner possible. - Emphasizes clinical aspects of immunology, including disease pathogenesis, the development of novel therapies based on basic science, and an appendix of clinical cases for real-world application. - Provides top-notch instruction from experienced teachers, course directors, and lecturers led by well-known editor and author Dr. Abul Abbas. - Features a highly readable writing style and practical organization, now with fully revised content and updated images to reflect recent important advances in today's understanding of the immune system. - Presents information in a format and style that maximizes usefulness to students and teachers studying medicine, allied health fields, and biology. - Contains numerous features designed to help students understand key immunologic concepts: high-quality illustrations, practical tables, chapter outlines, bolded key points, and focus questions in every chapter for self-assessment and review. - Evolve Instructor site with a downloadable image bank is available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com