The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has probably been the most important disease to emerge in the 21st century. This viral zoonotic disease has been a significant cause of morbidity and mortality worldwide, but with a higher impact in low- and middle-income countries of Africa, Asia, and Latin America. Up to December 4, 2022, more than 645,195,564 cases had been reported globally, with 6,640,845 deaths, and more than 13,054,668,703 doses of a vaccine had been given. Research has been of the utmost importance in the COVID-19 crisis: a great deal of knowledge was gathered between December 2019 and December 2022. Appropriate evidence-based management and the development of safe and effective vaccines have been key to controlling the virus. This book presents a selection of the last two years’ learning from research and clinical practice concerning SARS-CoV-2/COVID-19.

Zoonoses, diseases transmitted from animals to humans, hold immense global significance, impacting public health, economies, and ecosystems. Adopting the One Health approach, which recognizes the interconnectedness of human, animal, and environmental health, is crucial in tackling these challenges. Zoonotic diseases pose significant public health threats. Diseases like rabies, Ebola, and influenza have claimed countless lives worldwide. Without proper management, these diseases can rapidly escalate into pandemics, as seen with the COVID-19 pandemic, originating from a zoonotic transmission. The health of humans and animals are intricately linked, making collaborative efforts essential for disease prevention and control. Zoonoses have profound economic implications. Outbreaks can devastate agricultural sectors, leading to loss of livestock, reduced productivity, and trade restrictions. For instance, the 2001 foot-and-mouth disease outbreak in the United Kingdom resulted in billions of dollars in economic losses. Addressing zoonoses through a One Health approach can safeguard livelihoods and ensure food security. Furthermore, zoonotic diseases impact biodiversity and ecosystems. Diseases like West Nile virus and Lyme disease can affect wildlife populations, disrupting ecosystems and biodiversity. Additionally, habitat destruction and wildlife trafficking increase the likelihood of zoonotic spillover events. We can mitigate these risks and preserve ecosystem integrity through conservation efforts and sustainable land-use practices. The global importance of zoonoses cannot be overstated. By embracing the One Health approach, we can address these complex challenges comprehensively. Collaboration between human and veterinary medicine, environmental science, and other disciplines is essential for effective disease surveillance, prevention, and control. By prioritizing the health of people, animals, and the environment, we can build a safer, healthier future for all.

Since the end of December 2019, the world has been battling with a global health emergency called COVID-19. This ongoing pandemic has claimed millions of lives worldwide and made a serious impact on global healthcare. The information and facts about the virus and the pandemic are constantly evolving, expanding and are present in a scattered manner. Above all, various rumors and false information are also spreading through word of mouth or social media in relation to the pandemic. In situations like this, it becomes hard for a common person as well as professionals to keep track of the fundamental concepts, ongoing scientific advancements and differentiate between the facts and myths. COVID-19 and SARS-CoV-2: The Science and Clinical Application of Conventional and Complementary Treatments covers the fundamental concepts regarding SARS-CoV-2 and COVID–19 as well as common concerns and issues ensuring optimal understanding of the latest basic science and clinical content. The comparative coverage of Conventional Medical Science with Complementary and Alternative Systems of Medicine in relation to the ongoing pandemic makes this book unique compared to other books available on COVID-19. Written in textbook format and in semi-technical style, it provides basic to advanced concepts and multidimensional clinical perspectives keeping in mind the diverse needs of academicians, researchers, students and common people. Key Features: Contains simple, lucid and concise presentation of contents Emphasizes core knowledge and concepts Presents evidence based and up to date information from a multidisciplinary perspective Includes illustrations with good quality diagrams and colored photographs for ease of understanding. COVID-19 and SARS-CoV-2 covers concepts and protocols from holistic perspective relating to core Molecular Biology of SARS-CoV-2, Clinical and Therapeutic Aspects, Multidisciplinary Treatment and Management Strategies like Conventional Pharmacological Treatments, Vaccines, Ayurveda, Homoeopathy, Holistic Nutrition Therapy, Nutraceutical Therapy, Biochemic Medicine, and Issues and Concerns relating to Public Health and Ongoing Advances in Research in relation to COVID-19. Written in semi-technical language easily understandable by readers from all domains, this book provides multidisciplinary perspective, knowledge and understanding regarding COVID-19 in one place, thus bridging the knowledge gap that exists between Conventional Sciences and Complementary and Alternative Medicine Systems.

Since the end of 2019, Coronavirus disease 2019 (COVID-19), which caused more than 6 million deaths worldwide, immediately gained attention as a major public health issue. The clinical spectrum of COVID-19 encompasses a wide range of conditions, from a minor upper respiratory tract infection to severe interstitial pneumonia with respiratory and even multi-organ failure and a high in-hospital mortality. This unpredictability encouraged the development of tailored vaccination tactics to control the viral propagation and slow the progression of the disease. During the pandemic, a vast amount of clinical and laboratory data was gathered, allowing researchers to learn more about the progression of the disease as well as the efficacy and safety of the anti-SARS-Cov-2 vaccine.

Written by physicians and scientists with expertise in this evolving area, Textbook of SARS-CoV-2 and COVID-19 provides a coherent, readable, and clinically relevant review of the biology, epidemiology, pathophysiology, immunology, clinical features, current treatment, and prevention strategies for the SARS-CoV-2 virus. Using both a systemic and topic-based approach, it summarizes and clarifies the extensive literature published on SARS-CoV-2 and COVID-19, includes a comprehensive bibliography, and provides answers to clinical questions at the point of care from multiple specialty perspectives. - Includes dedicated chapters for pulmonary, cardiac, neurological, and oral manifestations of COVID-19. - Covers therapeutics and novel therapeutic targets of SARS-CoV-2 and COVID-19. - Addresses the diagnostic and management challenges of COVID-19 in the emergency department. - Discusses COVID-19 in special populations, including the effect of SARS-CoV-2 infection in pregnant mothers and to the fetus and newborn. - Provides a systematic overview and comparison of vaccines that are approved and in development.

Linking Neuroscience and Behavior in COVID-19 examines the impact of the virus and pandemic on behavior and mental health. Chapters look at those with pre-existing conditions, including dementia and multiple sclerosis, and how the pandemic has burdened them further. There is also discussion on the mental health consequences the pandemic has had and continues to have on the broad populace, including depression and anxiety, as well as neurological effects of the virus itself. Finally, managing care and treatment of conditions - those preceding, caused by, or emerging for the first time during the pandemic are also detailed. - Discusses the impact of the COVID-19 pandemic and the virus itself on behavior and psychology - Examines comorbidities including Parkinson's disease, neuroinflammation, and autism spectrum disorders - Outlines the management and care for coexisting conditions including brain tumors, multiple sclerosis, and ischemic stroke - Features chapters on the severe damage to the nervous system which may be caused by SARS-CoV-2 infection including myelitis - Contains chapters with key facts, dictionary of terms, summary points, applications to other areas pertinent to each chapter, and policies and procedures

National Book Award finalist Breathless tells the story of the worldwide scientific race to decipher the coronavirus SARS-CoV-2, trace its source, and make possible the vaccines to fight the Covid-19 pandemic—a “luminous, passionate account of the defining crisis of our time.” (The New York Times). Breathless is a “gripping” (The Atlantic) but “clear-eyed analysis” (Time) of SARs-CoV-2 and its fierce journey through the human population, as seen by the scientists who study its origin, its ever-changing nature, and its capacity to kill us. David Quammen expertly shows how strange new viruses emerge from animals into humans as we disrupt wild ecosystems and how those viruses adapt to their human hosts, sometimes causing global catastrophe. He explains why this coronavirus will probably be a “forever virus,” destined to circulate among humans and bedevil us endlessly, in one variant form or another. As scientists labor to catch it, comprehend it, and control it, with their high-tech tools and methods, the virus finds ways of escape. Based on interviews with nearly one hundred scientists, including leading virologists in China and around the world, Quammen explains that: -Infectious disease experts saw this pandemic coming -Some scientists, for more than two decades, warned that “the next big one” would be caused by a changeable new virus—very possibly a coronavirus—but such warnings were ignored for political or economic reasons -The precise origins of this virus may not be known for years, but some clues are compelling, and some suppositions can be dismissed -And much more Written by “one of our finest explainers of the natural world for decades” (Chicago Tribune), This “compelling and terrifying” (The New York Times) account is an unparalleled look inside the frantic international race to understand and control SARS-CoV-2—and what it might mean for the next potential global health crisis.