This book collects the state of the art of the antioxidants from the clinical and experimental approaches in order to bring a better understanding of the mechanisms and useful therapies for these diseases. We hope that it can indicate new "current trends" for identifying new aspects regarding this scientific problem involving not only anatomical and functional, but also clinical questions.

Atherosclerosis is a degenerative condition in which arteries build up deposits called plaques (atheromas) which consist of lipids (mainly cholesterol), connective tissue and smooth muscle cells originating from the arterial wall. Plaques develop quietly over a period of years and are unnoticeable until there is an interruption in the normal flow of blood. Plaques may partially or totally block the blood's flow through an artery. Two things that can happen where plaques occur are: bleeding (hemorrhage) into the plaque; and formation of a blood clot (thrombus) on the plaque's surface. Atherosclerosis affects large and medium-sized arteries. The type of artery and where the plaque develops varies with each person. Atherosclerosis research has witnessed startling progress in recent years, partially due to new drugs as well as to new breakthroughs in molecular medicine.

This monograph will bring out the state-of-the-art advances in the dynamics of cholesterol transport and will address several important issues that pertain to oxidative stress and inflammation. The book is divided into three major sections. The book will offer insights into the roles of specific cytokines, inflammation, and oxidative stress in atherosclerosis and is intended for new researchers who are curious about atherosclerosis as well as for established senior researchers and clinicians who would be interested in novel findings that may link various aspects of the disease.

Pharmacology is a rapidly progressing area of biomedical research, with new developments surfacing at regular intervals, constantly revolutionizing drug therapy for disease states. The interaction of this discipline with other biomedical sciences has opened up new vistas and opportunities in drug design and development. Basic and clinical concepts in the mechanism and use of drugs are carefully integrated into hypotheses, which are aimed at the maintenance of a critical balance between health and disease. Current Trends in Pharmacology is a comprehensive collection of topics highly significant in the current health scenario. The book comprises a combination of articles in clinical and experimental pharmacology and toxicology from the viewpoint of both basic and clinical scientists. It also details recent developments in the basic aspects of drug action in some very relevant disease states like hypertension, atherosclerosis, arrhythmia, stroke, tuberculosis, hospital acquired pneumonia, and cancer. It also highlights the applied issues relating to rational use of drugs. The contributing authors are leading experts in their respective fields and have presented the topics in a lucid and comprehensive manner

First multi-year cumulation covers six years: 1965-70.

Biomarkers are any measurable biochemical characteristics of an organism that reflect a particular physiological state. Biomarkers can take many different forms including particular proteins or peptides, antibodies, cell types, metabolites, hormones, enzyme levels, compounds related to genomics, etc. A biomarker can also be a substance introduced into a patient to assess the internal organ systems role. In medicine, biomarkers considered as compounds isolated from serum, urine, or other fluids, can be used as an indicator of the presence or severity of a particular disease state. The use of biomarkers is becoming a fundamental practice in medicine, Biomarker research involves a significantly greater scope of laboratory medicine. This monograph presents information on several types of biomarkers for general pathologies (preeclampsia, metabolic syndrome, iron metabolism, bone disease, liver function, renal function), cardiovascular pathology (including atrial fibrillation, peripheral artery disease, thrombotic disorders) and sepsis. Additional information on endocrine and salivary biomarkers is also presented. New Trends in Biomarkers and Diseases: An Overview is an ideal reference for medical students, pathology trainees and clinical researchers seeking information on biomarkers in medicine.

This volume is the proceedings of the Fifth International Conference on Fluid Mechanics (ICFM-V), the primary forum for the presentation of technological advances and research results in the fields of theoretical, experimental, and computational Fluid Mechanics. Topics include: flow instability and turbulence, aerodynamics and gas dynamics, industrial and environmental fluid mechanics, biofluid mechanics, geophysical fluid mechanics, plasma and magneto-hydrodynamics, and others.

Salient features of the book: - All chapters are related to the advances in cardiovascular risks.; - Chapters are written by renowned authors globally. - Chapters are lucid and easy to understand. - Chapters are useful for clinicians, medical practitioners, researchers, teachers, and students. - Chapters include flow charts, diagrams, and tables for easy comprehension of overall risks of cardiovascular disease. - Chapters generate awareness among common people about the risks so that the cost of intensive care units can be prevented, thus the economy of the country.