Lumpy skin disease (LSD) is a vector-borne disease of cattle and Asian water buffalo that is included on the OIE (World Organisation for Animal Health) list of notifiable diseases. In July 2019 LSD was introduced to Bangladesh, China and India and then spread to Nepal and Bhutan and in 2020 to various provinces of China and India. A qualitative risk assessment was conducted to assess the likelihood of introduction and/or spread of LSD in 23 countries in South, East and Southeast Asia based on information available up to 31 October 2020. The economic impact of LSD for South, East and Southeast countries was estimated to be up to USD 1.45 billion in direct losses of livestock and production. These losses may be higher, due to the severe trade implications for infected countries. This document provides an overview of LSD control approaches, including prevention. The cost-effectiveness estimation demonstrates a strong economic justification for vaccination and advocates for a regional approach to harmonize control measures.

PRINCIPLES OF GOAT DISEASE AND PREVENTION Learn to diagnose, treat, and clinically manage a wide variety of diseases in goats?? In Principles of Goat Disease and Prevention, veterinary medicine expert Dr. Tanmoy Rana delivers a singularly informative resource covering infectious diseases affecting ruminant animals. The book offers key insights into the most important aspects of common and unusual diseases affecting goats, providing clinical management best practices for veterinary practitioners engaged in the diagnosis and treatment of ruminant diseases.?? The author explains ruminant disease, as well as its diagnosis and treatment, systematically, explaining the etiopathogenesis of various pathogens, clinical symptoms, disease prevention and control, and the most recent advances in identifying and treating diseases in goats. Readers will also find: A thorough introduction to managing nutrition in goats Comprehensive explorations of the handling and restraining of goats for the purpose of veterinary treatment Practical discussions of the collection, preservation, processing, and shipment of clinical materials in the treatment of goats Fulsome treatments of parasitic, bacterial, fungal, viral, and other diseases of goats, as well as the management of pain from surgery and lameness Perfect for undergraduate, postgraduate, and doctoral students studying veterinary medicine, Principles of Goat Disease and Prevention will also benefit practitioners and students with an interest in studying or preventing disease in ruminants.????

First multi-year cumulation covers six years: 1965-70.

2. Virological Findings. 90 3. Immunity. . . . . 90 C. Secondary Dengue: Dengue Hemorrhagic Fever and the Shock Syndrome 92 1. General Remarks. . . . . . . . . . . . . . 92 2. Clinical Course and Clinical Laboratory Findings 93 3. Virological and Serological Findings. . . 95 4. Immunopathology of Secondary Dengue. 98 XI. Immunization. . . . . . . . . . . . . . . 104 A. Anamnestic Immune Responses in Sequential Infections With Dengue and Other Group B Togaviruses . . . . . . . . 104 1. Results With Members of the Dengue Subgroup 104 2. Results With Dengue and Other Flaviviruses. 107 B. Dengue Vaccines for Use in Man 108 XII. Opportunities for the Future 113 Acknowledgments. 114 References. . . . . . . . . . . 114 I. Introduction Dengue fever is a mosquito-transmitted disease of man which has afflicted untold millions of people over the past two centuries. It is caused by viruses classified as a subgroup of the group B togaviruses. Along with other members of that group as well as group A, the dengue viruses have been investigated intensively during recent years. Certain unique aspects of their structure, composition, antigenicity, replication, and antigenic relationships have established the togavirus family as quite distinct from other families of enveloped RNA viruses (see recent review of PFEFFERKORN and SHAPIRO, 1974). The basic studies leading to this conclusion have coincided with epidemiological field investigations which have resulted in a continuing increase in the number of viruses now designated as group A or B togaviruses. This, in turn, has led to a growing appreciation of their immense importance as actual or potential pathogens of man and beast.